1
Jeffrey A Hubbell, Chandrashekhar P Pathak, Amarpreet S Sawhney, Neil P Desai, Jennifer L Hill, Syed F A Hossainy: Gels for encapsulation of biological materials. Board of Regents The University of Texas System, Arnall Golden & Gregory, January 12, 1999: US05858746 (491 worldwide citation)

Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particula ...


2
Jeffrey A Hubbell, Chandrashekhar P Pathak, Amarpreet S Sawhney, Neil P Desai, Jennifer L Hill: Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers. Board of Regents The University of Texas System, Kilpatrick & Cody, April 25, 1995: US05410016 (484 worldwide citation)

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hy ...


3
Mark W Grinstaff, Patrick Soon Shiong, Michael Wong, Paul A Sandford, Kenneth S Suslick, Neil P Desai: Composition useful for in vivo delivery of biologics and methods employing same. Vivorx Pharmaceuticals, Stephen E Pretty Schroeder Brueggemann & Clark Reiter, March 12, 1996: US05498421 (260 worldwide citation)

In accordance with the present invention, there are provided compositions useful for the in vivo delivery of a biologic, wherein the biologic is associated with a polymeric shell formulated from a biocompatible material. The biologic can be associated with the polymeric shell itself, and/or the biol ...


4
Jeffrey A Hubbell, Chandrashekhar P Pathak, Amarpreet S Sawhney, Neil P Desai, Syed F A Hossainy: Gels for encapsulation of biological materials. The Board of Regents the Univeristy of Texas System, Lyon & Lyon, June 25, 1996: US05529914 (221 worldwide citation)

This invention provides novel methods for the formation of biocompatible membranes around biological materials using photopolymerization of water soluble molecules. The membranes can be used as a covering to encapsulate biological materials or biomedical devices, as a "glue" to cause more than one b ...


5
Neil P Desai, Patrick Soon Shiong, Paul A Sandford, Mark W Grinstaff, Kenneth S Suslick: Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor. VivoRx Pharmaceuticals, Stephen E Pretty Schroeder Brueggemann & Clark Reiter, August 8, 1995: US05439686 (194 worldwide citation)

In accordance with the present invention, there are provided compositions for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug taxol) in which the pharmacologically active agent is delivered in a soluble form or in the form of suspend ...


6
Jeffrey A Hubbell, Chandrashekhar P Pathak, Amarpreet S Sawhney, Neil P Desai, Jennifer L Hill West, Syed F A Hossainy: Gels for encapsulation of biological materials. Board of Regents The University of Texas System, Arnall Golden & Gregory, November 12, 1996: US05573934 (193 worldwide citation)

Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particula ...


7
Neil P Desai, Chunlin Tao, Andrew Yang, Leslie Louie, Tianli Zheng, Zhiwen Yao, Patrick Soon Shiong, Shlomo Magdassi: Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof. Vivorx Pharmaceuticals, Stephen E Reiter, Gray Cary Ware & Freidenrich, June 29, 1999: US05916596 (180 worldwide citation)

In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug paclitaxel) in which the pharmacologically active agent is delivered in the form of susp ...


8
Neil P Desai, Patrick Soon Shiong: Compositions and methods for administration of pharmacologically active compounds. American BioScience, Stephen E Reiter, Foley & Lardner, March 25, 2003: US06537579 (143 worldwide citation)

In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug paclitaxel) in which the pharmacologically active agent is delivered in the form of susp ...


9
Neil P Desai, Patrick Soon Shiong: Methods and compositions useful for administration of chemotherapeutic agents. Vivorx Pharmaceuticals, Stephen E Reiter, Gray Cary Ware & Freidenrich, August 1, 2000: US06096331 (142 worldwide citation)

In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of a pharmaceutically active agent, wherein the agent is associated with a polymeric biocompatible material.


10
Neil P Desai, Patrick Soon Shiong: Methods and formulations of cremophor-free taxanes. American BioScience, Stephen E Reiter, Foley & Lardner, January 14, 2003: US06506405 (138 worldwide citation)

In accordance with the present invention, there are provided composition and methods useful for the in vivo delivery of a pharmaceutically active agent, wherein the agent is associated with a polymeric biocompatible material.