1
Nathan W Levin, Gerard A Zasuwa: Automated hemodialysis control based upon patient blood pressure and heart rate. Henry Ford Hospital, Barnes Kisselle Raisch Choate Whittemore & Hulbert, December 1, 1987: US04710164 (92 worldwide citation)

A method and system for continuously monitoring patient heart rate and blood pressure during hemodialysis and for automatically controlling fluid extraction rate and/or dialysate sodium concentration in the event that blood pressure and/or heart rate indicate onset or impending onset of a patient hy ...


2
Fansan Zhu, Nathan W Levin: Device and method for monitoring and controlling physiologic parameters of a dialysis patient using segmental bioimpedence. Renal Research Institute, Kenyon & Kenyon, September 2, 2003: US06615077 (49 worldwide citation)

The present invention includes a method of determining the dry body weight of a patient undergoing dialysis by means of segmental bioimpedance analysis. In preferred embodiments, dry body weight is determined by comparison to the bioimpedance values of normal subjects or by monitoring changes in bio ...


3
Fansan Zhu, Nathan W Levin: Device and method for monitoring and controlling physiologic parameters of a dialysis patient using segmental bioimpedance. Renal Research Institute, Kenyon & Kenyon, June 5, 2007: US07228170 (18 worldwide citation)

The present invention includes a method of determining the dry body weight of a patient undergoing dialysis by means of segmental bioimpedance analysis. In preferred embodiments, dry body weight is determined by comparison to the bioimpedance values of normal subjects or by monitoring changes in bio ...


4
Jochen G Raimann, Erik Lars Penne, Stephan Thijssen, Peter Kotanko, Nathan W Levin: Method of controlling diffusive sodium transport in dialysis. Fresenius Medical Care Holdings, Hamilton Brook Smith & Reynolds P C, August 27, 2013: US08518260 (18 worldwide citation)

A method of controlling diffusive sodium transport from the dialysate solution to the blood of a patient undergoing hemodialysis treatment or from the blood to the dialysate solution includes calculating SNa+average, an average of the patient's historic serum sodium concentrations, and estimating SN ...


5
Nathan W Levin, Daniel Schneditz, Fansan Zhu: Methods and apparatus for measuring the volume of fluid in the peritoneal cavity. Maurice M Klee, April 8, 2008: US07354417 (9 worldwide citation)

Methods and apparatus for determining peritoneal cavity fluid volume include four groups of two electrodes applied to a subject's skin. Measuring electrodes (MLL, MRL) are applied to the subject's loins, measuring electrodes (MLB, MRB) are applied to the subject's buttocks, and upper and lower curre ...


6
Peter Kotanko, Nathan W Levin: Method of removing protein-bound deleterious substances during extracorporeal renal replacement treatment. Fresenius Medical Care Holdings, Hamilton Brook Smith & Reynolds P C, June 26, 2012: US08206591 (4 worldwide citation)

The invention is directed to a method of removing a deleterious substance bound to a protein in blood of a patient by introducing a displacer substance into the blood under conditions in which the displacer substance replaces deleterious substance bound to the protein, thereby resulting in additiona ...


7
Fansan Zhu, Nathan W Levin: Device and method for the determination of dry weight by continuous measurement of resistance and calculation of circumference in a body segment using segmental bioimpedance analysis. Fresenius Medical Care Holdings, Kenyon & Kenyon, September 21, 2010: US07801598 (3 worldwide citation)

A method and device for continuously calculating the circumference of a body segment is based on the continuous measurement of the extracellular resistance of the body segment. Also disclosed is a method and device for determining the dry weight of a dialysis patient wherein the time at which the dr ...


8
Fansan Zhu, Nathan W Levin: Device and method for performing electrical impedance tomography. Renal Research Institute, Kenyon & Kenyon, February 17, 2009: US07491174 (2 worldwide citation)

A system for performing electrical impedance tomography. The system includes a first set of electrodes positioned in a first plane and a second set of electrodes positioned in a second plane. The system also includes a third set of electrodes positioned in a third plane between the first and second ...


9
Nathan W Levin, Fansan Zhu: Bioimpedance methods and apparatus. Renal Research Institute, Maurice M Klee, September 4, 2012: US08257280 (1 worldwide citation)

Methods and apparatus for providing bioimpedance analysis are provided. In certain aspects, equivalent circuit frequency response models are provided which lead to improved correlations with MRI data. The frequency response models take account of body composition, including the fat component of a bo ...


10
Peter Kotanko, Stephan Thijssen, Len Usvyat, Nathan W Levin: Method of identifying when a patient undergoing hemodialysis is at increased risk of death. Fresenius Medical Care Holdings, Hamilton Brook Smith & Reynolds P C, February 12, 2019: US10203321

The invention is directed to a method of identifying a patient undergoing periodic hemodialysis treatments at increased risk for death that includes determining at least one of the patient's clinical or biochemical parameters, consisting of serum bicarbonate concentration level, serum potassium conc ...