1
Narr Berthold Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Benzimidazoles, drugs containing these compounds and process for their preparation.. Thomae Dr K, October 17, 1990: EP0392317-A2 (78 worldwide citation)

The invention relates to benzimidazoles of the formula in which R1 to R6 are defined as in claim 1, their 1- and 3-isomer mixtures and their acid addition salts, which have useful properties. The novel compounds are in particular angiotensin II antagonists.


2
Nickl Josef Dr Dipl Chem, Haarmann Walter Dr, Ballhause Helmut, Weisenberger Johannes Dr Dipl, Heckel Armin Dr Dipl Chem, Mueller Erich Dr Dipl Chem, Narr Berthold Dr Dipl Chem: Sulfonylaminoethyl compounds, medicines containing these compounds and process for their preparation.. Thomae Dr K, September 17, 1986: EP0194548-A2 (46 worldwide citation)

Sulphonylaminoethyl compounds of the formula in which R1 denotes a phenyl group which is optionally mono- or disubstituted by a methyl group or a halogen atom, where the substituents can be identical or different, a biphenylyl group which is optionally substituted by a halogen atom, or a naphthyl, p ...


3
Hauel Norbert Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Ries Uwe Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Benzimidazol, medicaments containing them and process for their preparation.. Thomae Dr K, September 9, 1992: EP0502314-A1 (45 worldwide citation)

The invention relates to benzimidazoles of the general formula in which R1 to R4 are as defined in Claim 1, mixtures of the 1 and 3 isomers thereof, and the salts thereof, which have valuable properties. The compounds are, in particular, angiotensin antagonists.


4
Bomhard Andreas Dr Dipl Chem, Psiorz Manfred Dr Dipl Chem, Heider Joachim Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Noll Klaus Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Kobinger Walter Prof Dr, Lillie Christian Dr: Heteroaromatic amine derivatives, medicaments containing them and process for their preparation.. Thomae Dr K, December 10, 1986: EP0204349-A2 (33 worldwide citation)

Die vorliegende Erfindung betrifft neue heteroaromatische Aminderivate der allgemeinen Formel in der A eine -CH2-CH2-, -CH=CH- oder -C?2-CO-Gruppe und B eine Methylen-, Carbonyl- oder Thiocarbonylgruppe oder und B eine Methylengruppe, wobei das mit x gekennzeichnete Kohlenstoffatom jeweils mit dem P ...


5
Narr Berthold Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr, Entzeroth Michael Dr, Ries Uwe Dr: Benzimidazoles, medicaments containing them and process for their preparation.. Thomae Dr K, January 29, 1992: EP0468470-A1 (31 worldwide citation)

The invention relates to benzimidazoles of the general formula in which R1 to R4 are as defined in Claim 1, mixtures of their 1-, 3-isomers, and their salts, which have valuable properties. The novel compounds are, in particular, angiotensin antagonists.


6
Heider Joachim Dr Dipl Chem, Psiorz Manfred Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Noll Klaus Dr Dipl Chem, Lillie Christian Dr, Kobinger Walter Prof Dr, Dammgen Jurgen Dr: Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation.. Thomae Dr K, November 30, 1988: EP0292840-A2 (30 worldwide citation)

Cyclic amine derivatives of the formula in which A, B, E, G, R, R1, R2, m and n are as defined in Claim 1, their enantiomers, their diastereomers, their N-oxides and their acid addition salts have useful pharmacological properties, in particular a bradycardic action. The novel compounds can be prepa ...


7
Mueller Erich Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Noll Klaus Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Heider Joachim Dr Dipl Chem, Psiorz Manfred Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Van Meel Jacques Dr, Diederen Willi Dr: 2-aryl imidazoles, pharmaceutical compositions containing them and process for their preparation.. Thomae Dr K, January 28, 1987: EP0209707-A2 (29 worldwide citation)

2-Arylimidazoles of the formula in which R denotes a hydrogen atom or an alkyl group, Ar denotes a group of the formula A and B together with the two carbon atoms in between denote a group of the formula in which R1 denotes an alkylsulphenyl, alkylsulphinyl, alkylsulphonyl or alkylsulphoximino group ...


8
Ries Uwe Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Heterocyclic imidazoles, remedies containing them and processes for their preparation.. Thomae Dr K, February 12, 1992: EP0470543-A1 (17 worldwide citation)

The invention relates to heterocyclic imidazoles of the general formula in which A1 to A4 and R1 to R5 are as defined in Claim 1, their 1- and 3-isomer mixtures, their tautomers, their enantiomers and their acid addition salts, which have useful pharmacological properties. The novel compounds are an ...


9
Psiorz Manfred Dr Dipl Chem, Heider Joachim Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Noll Klaus Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Lillie Christian Dr, Kobinger Walter Prof Dr, Dammgen Jurgen Dr: Naphthalene and indane derivatives, medicaments containing these compounds and processes for their preparation.. Thomae Dr K, March 16, 1988: EP0259782-A1 (17 worldwide citation)

Naphthalene and indane derivatives of the formula in which the substituents have the meaning given in the description, their enantiomers, their diastereomers and their acid addition salts with inorganic or organic acids which have useful pharmacological properties, in particular a heart rate-reducin ...


10
Nickl Josef Dr Dipl Chem, Heckel Armin Dr Dipl Chem, Mueller Erich Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Weisenberger Johannes Dr Dipl, Eisert Wolfgang Prof Dr, Mueller Thomas Dr Dipl Chem: Benzenesulfonamido-indanyl-compounds, medicines containing these compounds and process for their preparation.. Thomae Dr K, January 20, 1988: EP0253321-A2 (16 worldwide citation)

Die Erfindung betrifft neue Benzolsulfonamido-indanylverbindungen der allgemeinen Formel in der R1 eine gegebenenfalls durch ein Halogenatom, eine Methyl- oder Methoxygruppe mono- oder disubstituierte Phenylgruppe, wobei die Substituenten gleich oder verschieden sein k├Ânnen, und R2 eine gegebenenfal ...



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