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Katsuo Shinozaki, Tomoyuki Yoneta, Masakazu Murata, Naoyoshi Miura, Kiyoto Maeda: 1,5 Benzodiazepine derivatives. Zeria Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt P C, May 29, 2001: US06239131 (28 worldwide citation)

1,5-Benzodiazepine derivatives represented by formula (I), salts thereof, and medicines containing the same as the active ingredient:


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Motoki Torizuka, Tomoji Aotsuka, Mitsuo Soeda, Kuniyoshi Ogura, Yoshiaki Tanaka, Hisayoshi Kato, Naoki Nakata, Naoyoshi Miura, Hikari Morita: Condensed benzene derivative. Zeria Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt, July 2, 1991: US05028604 (9 worldwide citation)

Novel condensed benzene derivatives having prolyl endopeptidase inhibitory, anti-hypoxic, and anti-amnesic activities are disclosed. The compounds are represented by the following (I), ##STR1## wherein A represents a methylene, ethylene, or propylene group, B represents a methylene or ethylene group ...


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Yoshiaki Tanaka, Tomoji Aotsuka, Naomi Kobayashi, Naoki Nakata, Kuniyoshi Ogura, Motoki Torizuka, Naoyoshi Miura, Heihachiro Arai: Amino acid imide derivatives, usage thereof, and medicinal composition containing the same. Zeria Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt, April 10, 1990: US04916146 (4 worldwide citation)

Novel N-substituted amino acid imide derivatives are disclosed. The compounds are represented by formula (I): ##STR1## wherein n represents an integer of 0 to 5, and X and Y, which may be the same or different, represent a methylene group or a sulfur atom, provided that not both X and Y are methylen ...


4
Masaaki Nagasawa, Hiroyasu Nishioka, Kazuyasu Asami, Naoyoshi Miura, Yutaka Shinozaki, Hitoshi Morita: Benzimidazole derivatives. Zeria Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt P C, April 26, 2005: US06884810 (1 worldwide citation)

A benzimidazole derivative of formula (1): (wherein R represents a hydrogen atom or a methoxy group, and n is 0 or 1) or a salt thereof; and a medicament containing the same. The compounds of the present invention, due to minimized difference in therapeutic effect between subjects, which difference ...


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Kuniyoshi Ogura, Tomoji Aotsuka, Motoki Torizuka, Mitsuo Soeda, Yoshiaki Tanaka, Hisayoshi Kato, Naoyoshi Miura, Noaki Nakata, Hikaru Morita, Akihiro Okubo: Phenylalkanoylamine derivatives, process for preparing the same, and usage of the same. Zeria Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt, March 30, 1993: US05198450

An agent for treating or preventing cerebral circulation disorder, cerebral metabolism disorder, or memory disturbance is disclosed. The agent comprises as an effective component a phenylalkanoylamine derivative represented by the following formula (I), ##STR1## wherein A represents a 1,3-thiazolidi ...


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Katsuo Shinozaki, Masakazu Murata, Kiyoto Maeda, Hiroaki Taguchi, Nobuo Kawase, Naoyoshi Miura: Calcium salts of 1,5-benzodiazepine derivatives, process for producing the salts and drugs containing the same. Oblon Spivak Mcclelland Maier & Neustadt PC, May 22, 2003: US20030096809-A1

Provided are calcium salts of a 1,5-benzodiazepine derivative represented by the following formula (I): 1 (wherein, R1 represents a lower alkyl group, R2 represents a phenyl or cyclohexyl group, and Y represents a single bond or a lower alkylene group); a process for preparing the salts; and drugs c ...


9
Masaaki Nagasawa, Hiroyasu Nishioka, Kazuyasu Asami, Naoyoshi Miura, Yutaka Shinozaki, Hitoshi Morita: Benzimidazole derivatives. Oblon Spivak Mcclelland Maier & Neustadt PC, December 25, 2003: US20030236411-A1

A benzimidazole derivative of formula (1): 1 (wherein R represents a hydrogen atom or a methoxy group, and n is 0 or 1) or a salt thereof; and a medicament containing the same. The compounds of the present invention, due to minimized difference in therapeutic effect between subjects, which differenc ...


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Masaaki Nagasawa, Hiroyasu Nishioka, Kazuyasu Asami, Naoyoshi Miura, Hideki Nakamura, Hitoshi Morita: 1-N-Aminobenzimidazole derivatives. Zeria Pharmaceutical, Oblon Spivak Mcclelland Maier & Neustadt PC, July 7, 2005: US20050148634-A1

Provided are 1-N-aminobenzimidazole derivatives represented by the following formula (I): wherein R1 and R2 each represents a substituted or unsubstituted alkyl group or the like, R3, R5 and R6 each represents an alkyl group, alkoxy group, hydrogen atom or the like, R4 represents a substituted or un ...