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Olaf B Kinstler, Nancy E Gabriel, Christine E Farrar, Randolph B DePrince: N-terminally chemically modified protein compositions and methods. Amgen, Robert B Winter, Karol M Pessin, Steven M Odre, October 20, 1998: US05824784 (274 worldwide citation)

Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and relate ...


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Mary P Roberts, Nancy E Gabriel: Unilamellar lipid vesicles and method for their formation. Massachusetts Institute of Technology, Hamilton Brook Smith & Reynolds, May 1, 1990: US04921706 (125 worldwide citation)

This invention relates to unilamellar lipid vesicles comprised of short-chain phospholipids and long-chain phospholipids and a method for making the vesicles. The short-chain phospholipids are comprised of fatty acids with fewer than 9 carbons atoms and the long-chain phospholipids are comprised of ...


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Olaf B Kinstler, Nancy E Gabriel, Christine E Farrar, Randolph B DePrince: N-terminally chemically modified protein compositions and methods. Amgen, Craig A Crandall, Ron K Levy, Steven M Odre, November 16, 1999: US05985265 (88 worldwide citation)

Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel chemically modified G-CSF compositions and related methods of ...


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Nancy E Gabriel, Christine E Farrar: N-terminally chemically modified protein compositions and methods. Amgen, Marshall Gerstein & Borun, August 15, 2006: US07090835 (4 worldwide citation)

Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and relate ...


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Olaf B Kinstler, Nancy E Gabriel, Christine E Farrar, Randolph B DePrince: N-terminally chemically modified protein compositions and methods. Amgen, Marshall Gerstein & Borun, September 16, 2004: US20040181035-A1

Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and relate ...


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Olaf B Kinstler, Nancy E Gabriel, Christine E Farrar, Randolph B DePrince: N-terminally chemically modified protein compositions and methods. Amgen, Marshall Gerstein & Borun, October 19, 2006: US20060233746-A1

Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and relate ...


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Olaf B Kinstler, Nancy E Gabriel, Christine E Farrar, Randolph B DePrince: N-terminally chemically modified protein compositions and methods. Amgen, Marshall Gerstein & Borun, December 9, 2010: US20100310510-A1

Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and relate ...


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