1
David B Fenske, Pieter R Cullis, Kim Wong, Maurer Norbert, Johanna M Leenhouts, Elisabeth Maurer, Nancy Boman: Ionophore-mediated liposome loading. University of British Columbia, Townsend and Townsend and Crew, November 17, 1998: US05837282 (46 worldwide citation)

Novel methods are provided for loading a weakly basic drug into liposomes utilizing an electoneutral transport system. In these methods, ionophores are utilized with liposomes having a metal ion gradient to facilitate the exchange of metal ions for protons. The transported metal ion will, in some em ...


2
Ryo Kubota, Nancy Boman, Claes Bavik, Ian L Scott: Pharmacology of Visual Cycle Modulators. Acucela, Wilson Sonsini Goodrich & Rosati, January 6, 2011: US20110003895-A1

Described herein are methods for the treatment of an ophthalmic disease or disorder comprising the administration of non-retinoid visual cycle modulators.