1
Schmidt Gunter Dr, Brandes Arndt Dr, Angerbauer Rolf Dr, Loegers Michael Dr, Mueller Gliemann Matthias Dr, Schmeck Carsten Dr, Bremm Klaus Dieter Dr, Bischoff Hilmar Dr, Schmidt Delf Dr, Schuhmacher Joachim Dr, Giera Henry Dr, Paulsen Holger Dr, Naab Paul Dr, Conrad Michael Dr, Stoltefuss Juergen: Cycloalkano-pyridine as cetp inhibitors. Bayer, January 14, 1998: EP0818448-A1 (95 worldwide citation)

Cycloalkano-pyridine compounds of formula (I) and their salts and N-oxides are new. A = 6-10C aryl (optionally up to penta-substituted by halo, NO2, OH, CF3, OCF3, 1-7C alkyl, 1-7C acyl, 1-7C hydroxyalkyl, 1-7C alkoxy or NR3R4); R3, R4 = H, phenyl or 1-6C alkyl; D = 6-10C aryl (optionally substitute ...


2
Zerbes Rudolf Dr, Naab Paul Dr, Franckowiak Gerhard Dr, Diehl Herbert Dr: One pot process for the preparation of 3-quinolonecarboxylic acid derivatives.. Bayer, June 14, 1995: EP0657448-A1 (8 worldwide citation)

The present invention relates to a one-pot process for the preparation of 7-heterocyclyl-substituted 3-quinolonecarboxylic acid derivatives. They have a strong antimicrobial action and include active compounds such as ofloxacin, ciprofloxacin or enrofloxacin.


3
Lanz Joachim Dr, Naab Paul Dr, Rosentreter Ulrich Dr: Process for the preparation of 7-amino-3- not (z)-1-propenyl-1-yl -3-cephem-4-carboxylic acid. Bayer, April 10, 1991: EP0421219-A2 (4 worldwide citation)

The invention relates to a process for the preparation of 7-amino- 3-[(Z)-1-propen-1-yl]-3-cephem-4-carboxylic acid, and processes for the preparation of intermediates leading to this compound.


4
Naab Paul Dr, Preiss Michael Dr: Nucleus halogenated 3-fluorotoluenes and process for their preparation.. Bayer, August 1, 1984: EP0114604-A1 (4 worldwide citation)

1. 3-fluorotoluenes halogenated in the nucleus, of the general formula see diagramm : EP0114604,P6,F1 in which Hal can be identical or different and denote chlorine, bromine or iodine.


5
Metzger Karl Georg Dr, Schrock Wilfried Dr, Habich Dieter Dr, Naab Paul Dr, Zeiler Hans Joachim Dr: Beta-lactam antibiotics, process for their preparation and their use as medicines.. Bayer, November 2, 1983: EP0092722-A1 (3 worldwide citation)

Die Erfindung betrifft 3-[beta]-(vic-Dihydroxyphenyl-methylenamino-2-oxo-imidazolidin)- und 3-[beta]-(vic-Dihydroxyphenyl-methylenamino-2,3-dioxo-piperazin)-1-carbonylaminoacetamido-azetidin-2-one mit einer Säurengruppierungan 1N, insbesondere Verbindungen der Formel 1 Verfahren zu ihrer Herstellung ...


6
Preiss Michael Dr, Schorsch Ulrich Dr, Haaf Arthur Dr, Naab Paul Dr, Zerbes Rudolf Dr: Process for the preparation of quinoline carboxylic acids for parenteral application.. Bayer, October 26, 1988: EP0287926-A2 (3 worldwide citation)

Solutions of quinolonecarboxylic acids for parenteral administration, of the formula I in which R, R, R, X and A have the meaning given in the description, and a process for their preparation.


7
Naab Paul Dr, Ertel Werner Dr: Process for the preparation of muzolimine.. Bayer, May 14, 1986: EP0180707-A1 (2 worldwide citation)

Improved process for the synthesis of 1-substituted 3-amino-5-pyrazolones, in which in a first step a hydrazine derivative is condensed with alkyl beta -amino- beta -alkoxyacrylate under acidic conditions and the intermediate is subjected in a second step to a ring closure reaction in strongly basic ...


8
Teller Werner Dr, Koebernick Wolfgang Dr, Haaf Arthur Dr, Naab Paul Dr, Preiss Michael Dr: Process for the preparation of symmetric 1,4-dihydropyridine-carboxylic esters.. Bayer, November 14, 1984: EP0124742-A2 (2 worldwide citation)

1. Processs for the preparation of symmetrical 1,4-dihydropyridines of the formula I see diagramm : EP0124742,P6,F1 in which R represents a phenyl radical which is optionally mono- or disubstituted by nitro and/or chlorine, and R1 represents a C1 -C4 -alkyl radical which is optionally substituted by ...


9
Samaan Samir Prof Dr, Lanz Joachim Dr, Naab Paul Dr, Rosentreter Ulrich Dr: 3-amino-tetrahydrocarbazol propanoic acid esters. Bayer, August 28, 1996: EP0728743-A1 (1 worldwide citation)

(3-amino)-tetrahydrocarbazole-propanoic acid esters of formula (I), and their salts, are new. R = alkyl contg. up to 10C.


10
Naab Paul Dr, Lange Willi, Teller Werner Dr: Method of preparing asymmetrical dihydropyridines.. Bayer, June 14, 1989: EP0319814-A2 (1 worldwide citation)

Nitrenedipine is prepared by reaction of an ylidene compound of the formula II (IIa) or (IIb) with an enamine compound of the formula (IIIa) or (IIIb) the reaction being carried out in an organic solvent in the presence of catalytic amounts of diisopropylamine acetate or dimethylbenzylamine acetate.