1
Cywin Charles, Pullen Steven S, Roth Gregory Paul, Snow Roger John, Fleck Roman Wolfgang, Takahashi Hidenori, Winters Michael, Qiao Lei, Nemoto Peter Allen, Moriarity Kevin J, Wang Ji, Bentzien Joerg, Cook Brian, Lo Ho Yin: Substituted benzimidazole compounds. Boehringer Ingelheim Pharmaceuticals, RAYMOND Robert P, February 19, 2004: WO/2004/014905 (8 worldwide citation)

Disclosed are substituted benzimidazole compounds of formula (I) wherein R¿1?, R¿2?, R¿3?, R¿4? and X¿a? are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders an ...


2
Cywin Charles, Pullen Steven S, Roth Gregory P, Snow Roger J, Fleck Roman W, Takahashi Hidenori, Winters Michael, Qiao Lei, Nemoto Peter A, Moriarity Kevin J, Wang Ji, Bentzien Joerg, Cook Brian, Lo Ho Yin: Substituted benzimidazole compounds. Boehringer Ingelheim Pharma, May 11, 2005: EP1529046-A1

Disclosed are substituted benzimidazole compounds of formula (I) wherein R>1234a< are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. A ...