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Robert Boock, Monica Rixman: Silicone based membranes for use in implantable glucose sensors. DexCom, Knobbe Martens Olson & Bear, November 3, 2009: US07613491 (381 worldwide citation)

Membrane systems incorporating silicone polymers are described for use in implantable analyte sensors. Some layers of the membrane system may comprise a blend of a silicone polymer with a hydrophilic polymer, for example, a triblock poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) pol ...


2
Robert Boock, Monica Rixman, James H Brauker, James R Petisce, Peter C Simpson, Mark Brister, Mark A Tapsak, Victoria Carr Brendel: Analyte sensor. DexCom, Knobbe Martens Olson & Bear, November 9, 2010: US07828728 (77 worldwide citation)

The present invention relates generally to membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the invention relates to novel silicone-hydrophilic polymer blend membranes, and to devices and implantable d ...


3
Robert Boock, Monica Rixman: Silicone based membranes for use in implantable glucose sensors. DexCom, Knobbe Martens Olson & Bear, September 24, 2013: US08543184 (5 worldwide citation)

Membrane systems incorporating silicone polymers are described for use in implantable analyte sensors. Some layers of the membrane system may comprise a blend of a silicone polymer with a hydrophilic polymer, for example, a triblock poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) pol ...


4
Robert Boock, Monica Rixman: Silicone based membranes for use in implantable glucose sensors. DexCom, Knobbe Martens Olson & Bear, November 22, 2011: US08064977 (3 worldwide citation)

Membrane systems incorporating silicone polymers are described for use in implantable analyte sensors. Some layers of the membrane system may comprise a blend of a silicone polymer with a hydrophilic polymer, for example, a triblock poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) pol ...


5
Robert Boock, Monica Rixman Swinney, Huashi Zhang, Michael J Estes, Kristina Lawrence: Polymer membranes for continuous analyte sensors. DexCom, Knobbe Martens Olson & Bear, November 3, 2015: US09173606 (1 worldwide citation)

Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The se ...


6
Robert Boock, Monica Rixman Swinney, Huashi Zhang, Michael J Estes, Kristina Lawrence: Polymer membranes for continuous analyte sensors. DexCom, Knobbe Martens Olson & Bear, November 3, 2015: US09173607 (1 worldwide citation)

Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The se ...


7
James H Brauker, Peter C Simpson, Robert Boock, Monica Rixman, Mark Brister: Analyte sensor. DexCom, Knobbe Martens Olson & Bear, July 17, 2018: US10022078

The present invention relates generally to biointerface membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the invention relates to novel biointerface membranes, to devices and implantable devices includ ...


8
Robert Boock, Monica Rixman Swinney, Huashi Zhang, Michael J Estes, Kristina Lawrence: Polymer membranes for continuous analyte sensors. DexCom, Knobbe Martens Olson & Bear, February 21, 2017: US09572523

Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The se ...


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James H Brauker, Peter C Simpson, Robert Boock, Monica Rixman, Mark Brister: Analyte sensor. Knobbe Martens Olson & Bear, March 1, 2007: US20070045902-A1

The present invention relates generally to biointerface membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the invention relates to novel biointerface membranes, to devices and implantable devices includ ...