1
Frank Elischweski, Jorn Kalinowski, Alfred Puhler, Nicole Dusch, Jurgen Dohmen, Mike Farwick, Georg Thierbach: Process for the preparation of pantothenic acid by amplification of nucleotide sequences which code for the ketopantoate reductase. Degussa, Pillsbury Winthrop, September 7, 2004: US06787334 (14 worldwide citation)

The invention relates to a process for the preparation and improvement of D-pantothenic acid-producing microorganisms by amplification of nucleotide sequences which code for ketopantoate reductase, in particular the panE gene, individually or in combination with one another, and optionally additiona ...


2
Brigitte Bathe, Stephan Hans, Mike Farwick, Thomas Hermann: Nucleotide sequences coding for the pknB gene. Degussa, Oblon Spivak McClelland Maier & Neustadt P C, September 12, 2006: US07105302 (11 worldwide citation)

An isolated polynucleotide which contains a polynucleotide sequence selected from the group comprising: (a) a polynucleotide which is at least 70% identical to a polynucleotide coding for a polypeptide containing the amino acid sequence of SEQ ID No. 2, (b) a polynucleotide coding for a polypeptide ...


3
Brigitte Bathe, Stephan Hans, Mike Farwick, Thomas Hermann: Nucleotide sequences coding for the pknB gene. Degussa, Oblon Spivak McClelland Maier & Neustadt P C, September 6, 2005: US06939692 (11 worldwide citation)

An isolated polynucleotide which contains a polynucleotide sequence selected from the group comprising: (a) a polynucleotide which is at least 70% identical to a polynucleotide coding for a polypeptide containing the amino acid sequence of SEQ ID No. 2, (b) a polynucleotide coding for a polypeptide ...


4
Frank Elischweski, Jorn Kalinowski, Alfred Puhler, Nicole Dusch, Jurgen Dohmen, Mike Farwick, Georg Thierbach: Mutant E. coli kiz strains for production of pantothenic acid. Degussa Huls, Pillsbury Madison & Sutro, January 9, 2001: US06171845 (9 worldwide citation)

The invention relates to a process for the preparation and improvement of D-pantothenic acid-producing microorganisms by amplification of nucleotide sequences which code for ketopantoate reductase, in particular the panE gene, individually or in combination with one another, and optionally additiona ...


5
Mike Farwick, Brigitte Bathe, Jennifer Brehme, Klaus Huthmacher: Process for the preparation of amino acids by using coryneform bacteria with attenuated 1-phosphofructokinase activity. Degussa, Smith Gambrell & Russell, July 26, 2005: US06921651 (7 worldwide citation)

The invention relates to a process for the preparation of L-amino acids. The process includes fermenting the coryneform bacteria producing the desired L-amino acid, in which at least the gene coding for 6-phosphofructokinase and/or the gene coding for 1-phosphofructokinase are/is attenuated, enrichi ...


6
Mechthild Rieping, Mike Farwick: Enterobacteriaceae strains over-expressing the yfiD gene for the fermentative production of L-amino acids. Degussa, Michael A Sanzo, Law Office of Michael A Sanzo, May 1, 2007: US07211415 (5 worldwide citation)

The present invention relates to a process for the production of L-amino acids by fermentation of recombinant microorganisms of the Enterobacteriaceae family, wherein a) the yfiD ORF and/or the pflB gene or nucleotide sequences coding for the gene products are overexpressed in the microorganisms pro ...


7

8
Mike Farwick, Klaus Huthmacher, Natalie Schischka, Brigitte Bathe, Walter Pfefferle, Michael Binder, Dieter Greissinger, Georg Thierbach: Nucleotide sequences which code for the cysD, cysN, cysK, cysE and cysH genes. Degussa, Oblon Spivak McClelland Maier & Neustadt P C, November 23, 2004: US06822085 (4 worldwide citation)

Nucleotide sequences from coryneform bacteria which code for the cysD, cysN, cysK, cysE and cysH genes and a process for the fermentative preparation of amino acids using bacteria in which the genes mentioned are enhanced, a process for the fermentative preparation of L-amino acids using coryneform ...


9
Mike Farwick, Brigitte Bathe, Thomas Hermann, Achim Marx, Walter Pfefferle: Process for the production of L-amino acids by fermentation using coryneform bacteria with an attenuated mqo gene. Degussa, Venable, Ann S Hobbs, May 23, 2006: US07049106 (4 worldwide citation)

A process for the production of an L-amino acid wherein coryneform bacteria (e.g. Coryneform glutamicum) in which expression of the mqo gene coding for malate quinone oxidoreductase is attenuated are fermented to produce a desired amino acid, and the amino acid is concentrated in the medium or cells ...


10
Mike Farwick, Brigitte Bathe, Thomas Hermann, Achim Marx, Walter Pfefferle: Process for the production of L-amino acids by fermentation using coryneform bacteria. Degussa, Ann S Hobbs, Venable, December 5, 2006: US07144724 (4 worldwide citation)

A process for the production of an L-amino acid wherein coryneform bacteria (e.g. Coryneform glutamicum) in which expression of the mqo gene coding for malate quinone oxidoreductase is attenuated are fermented to produce a desired amino acid, and the amino acid is concentrated in the medium or cells ...



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