1
Olof Mikael Trollsas, Donald G Wallace, Frank A DeLustro: Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use. Cohesion Technologies, Dianne E Reed, Reed & Associates, October 1, 2002: US06458889 (175 worldwide citation)

Crosslinkable compositions are provided that readily crosslink in situ to provide biocompatible, nonimmunogenic crosslinked biomaterials. The compositions contain at least three biocompatible, nonimmunogenic components having reactive functional groups thereon, with the functional groups selected so ...


2
Louis C Sehl, Olof Mikael Trollsas, Donald G Wallace, David Toman, Frank A DeLustro, Jacqueline A Schroeder, George H Chu: Methods for tissue repair using adhesive materials. Cohesion Technologies, Dianne E Reed, Mark L Warzel, Reed Intellectual Property Law Group, December 21, 2004: US06833408 (150 worldwide citation)

A method of tissue repair is provided using a biocompatible nonimmunogenic adhesive composition. The adhesive composition comprises collagen and a plurality of crosslinkable components having reactive functional groups thereon, with the functional groups selected so as to enable inter-reaction betwe ...


3
Donald G Wallace, Gregory M Cruise, Woonza M Rhee, Jacqueline Anne Schroeder, George T Coker III, Marcee M Maroney, Olof Mikael Trollsas: Rapid-gelling biocompatible polymer composition and associated methods of preparation and use. Cohesion Technologies, Dianne K Reed, Reed & Eberle, September 23, 2003: US06624245 (114 worldwide citation)

A method is provided for the rapid formation of a biocompatible gel, and may be carried out in situ, i.e., at a selected site within a patient's body. The method involves admixing a biocompatible crosslinking component A having m sulfhydryl groups wherein m≧2 and a biocompatible crosslinking ...


4
Craig Jon Hawker, James Lupton Hedrick, Olof Mikael Trollsas: Highly branched radial block copolymers. International Business Machines Corporation, Thomas A Beck, September 5, 2000: US06114458 (32 worldwide citation)

A branched radial block copolymer including the reaction product of a dendritic macromolecular initiator, and one or more chain extending monomers.


5
Syed Hossainy, Michael Ngo, Mikael Trollsas, John Stankus, Gene Michal: Methods and compositions for treating tissue using silk proteins. Abbott Cardiovascular Systems, Randy Shen, Blakely Sokoloff Taylor & Zafman, June 5, 2012: US08192760 (28 worldwide citation)

Compositions for forming a self-reinforcing composite biomatrix, methods of manufacture and use therefore are herein disclosed. Kits including delivery devices suitable for delivering the compositions are also disclosed. In some embodiments, the composition can include at least three components. In ...


6
Eugene Michal, Olof Mikael Trollsas, Shubhayu Basu: Modified two-component gelation systems, methods of use and methods of manufacture. Advanced Cardiovascular Systems, Blakely Sokoloff Taylor & Zafman, June 8, 2010: US07732190 (27 worldwide citation)

Compositions, methods of manufacture and methods of treatment for post-myocardial infarction are herein disclosed. In some embodiments, the composition includes at least two components. In one embodiment, a first component can include a first functionalized polymer and a substance having at least on ...


7
Louis C Sehl, Olof Mikael Trollsas, Donald G Wallace, David Toman, Frank A DeLustro, Jacqueline A Schroeder, George H Chu: Compositions and systems for forming crosslinked biomaterials and methods of preparation of use. AngioDevice International, Seed IP Law Group PLLC, February 8, 2011: US07883693 (24 worldwide citation)

Crosslinkable compositions are provided that readily crosslink in situ to provide biocompatible, nonimmunogenic crosslinked materials that may be used as adhesive compositions. The compositions comprise collagen and a plurality of crosslinkable components having reactive functional groups thereon, w ...


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George Y Daniloff, Louis C Sehl, Olof Mikael Trollsas, Jacqueline Schroeder, David M Gravett, Philip M Toleikis: Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use. AngioDevice International, Seed IP Law Group PLLC, November 29, 2011: US08067031 (19 worldwide citation)

Crosslinkable compositions are provided that readily crosslink in situ to provide crosslinked biomaterials. The composition contains at least two biocompatible, non-immunogenic components having reactive groups thereon, with the functional groups selected so as to enable inter-reaction between the c ...


10
Lothar W Kleiner, John Stankus, Nam D Pham, Michael H Ngo, Bozena Zofia Maslanka, Syed Faiyaz Ahmed Hossainy, Mikael Trollsas, Yiwen Tang: Bioabsorbable coating with tunable hydrophobicity. Abbott Cardiovascular Systems, Squire Patton Boggs, February 24, 2015: US08961589 (16 worldwide citation)

The present invention relates to implantable medical devices coated with polymer having tunable hydrophobicity and their use in the treatment of vascular diseases.