1
Michalakis Averkiou, Jeffry E Powers, Peter N Burns, David N Roundhill, Juin Jet Hwang: Ultrasonic diagnostic imaging of response frequency differing from transmit frequency. ATL Ultrasound, W Brinton Yorks Jr, March 9, 1999: US05879303 (124 worldwide citation)

An ultrasonic diagnostic imaging system and methods are described which produces ultrasonic images from harmonic echo components of a transmitted fundamental frequency. Preferably, a programmable digital filter is used to pass harmonic echo components for image processing to the exclusion of fundame ...


2
Michalakis Averkiou, Matthew Bruce, Jeffry E Powers: Ultrasonic diagnostic imaging with contrast agents. Advanced Technology Laboratories, W Brinton Yorks Jr, November 10, 1998: US05833613 (82 worldwide citation)

Apparatus and methods are disclosed for the detection and imaging of ultrasonic contrast agents. Ultrasonic apparatus is provided for coherent imaging of ultrasonic contrast agents, and for detecting harmonic contrast agents. The inventive apparatus includes a dual display for simultaneously viewing ...


3
Michalakis Averkiou, Jeffry E Powers, Peter N Burns, David N Roundhill, Juin Jet Hwang, Jeremy D Wiggins: Ultrasonic tissue harmonic imaging. ATL Ultrasound, W Brinton Yorks Jr, June 26, 2001: US06251074 (73 worldwide citation)

An ultrasonic diagnostic imaging system and methods are described which produce tissue harmonic ultrasonic images from harmonic echo components of a transmitted fundamental frequency. Fundamental frequency waves are transmitted by an array transducer to focus at a focal depth. As the transmitted wav ...


4
Michalakis Averkiou: Ultrasonic diagnostic imaging of nonlinearly intermodulated and harmonic frequency components. Koninklijke Philips Electronics, W Brinton Yorks Jr, August 27, 2002: US06440075 (35 worldwide citation)

An ultrasonic diagnostic imaging system and method are described for performing nonlinear echo signal imaging with harmonic and intermodulation product (sum or difference frequency) components. Both the harmonic and the intermodulation products are produced by nonlinear effects of tissue or contrast ...


5
Jeffry E Powers, Michalakis Averkiou, Matthew Bruce, Danny M Skyba, Robert R Entrekin, John D Fraser, Clifford R Cooley, Brent Stephen Robinson, David N Roundhill, Gary Allen Schwartz, Patrick René Pesque: Ultrasonic diagnostic imaging of the coronary arteries. Kininklijke Philips Electronics, W Brinton Yorks Jr, October 22, 2002: US06468216 (34 worldwide citation)

An ultrasonic imaging method and apparatus are described for imaging the coronary arteries of the heart. The vascular system is infused with an ultrasonic contrast agent. A volumetric region of the heart wall including a coronary artery is three dimensionally scanned. A projection image of the volum ...


6
Michalakis Averkiou, Jeffry E Powers, Matthew Bruce, Danny M Skyba: Realtime ultrasonic imaging of perfusion using ultrasonic contrast agents. January 9, 2001: US06171246 (29 worldwide citation)

Perfusion of tissue such as the myocardium by a microbubble contrast agent is imaged in realtime by a multiple pulse technique which uses low power transmit pulses which are sufficient to elicit a harmonic response from the microbubbles but are not high enough in power to cause substantial destructi ...


7
Jeffry E Powers, Michalakis Averkiou, Matthew Bruce, Danny M Skyba, Robert R Entrekin, John D Fraser, Clifford R Cooley, Brent Stephen Robinson, David N Roundhill, Gary Allen Schwartz, Patrick René Pesque: Three dimensional ultrasonic diagnostic imaging with high density hexagonal acquisition. Koninklijke Philips Electronics, W Brinton Yorks Jr, October 29, 2002: US06471650 (23 worldwide citation)

An ultrasonic imaging method and apparatus are described for imaging the coronary arteries of the heart. The vascular system is infused with an ultrasonic contrast agent. A volumetric region of the heart wall including a coronary artery is three dimensionally scanned. A projection image of the volum ...


8
David N Roundhill, Michalakis Averkiou: Ultrasonic diagnostic imaging of harmonic frequencies with speckle reduction processing. ATL Ultrasound, W Brinton Yorks Jr, June 1, 1999: US05908389 (18 worldwide citation)

An ultrasonic diagnostic imaging system and methods are described which produces ultrasonic images from harmonic echo components of a transmitted fundamental frequency. Preferably, a programmable digital filter is used to pass harmonic echo components for image processing to the exclusion of fundame ...


9
Jeffry E Powers, John Fraser, Michalakis Averkiou: Method of using a combination imaging and therapy transducer to dissolve blood clots. Koninklijke Philips Electronics, September 6, 2011: US08012092 (17 worldwide citation)

A combined ultrasound imaging and therapy transducer includes a linear array of imaging transducer elements. First and second linear arrays of therapy transducer elements extend longitudinally along respective first and second sides of the imaging transducer elements and are canted inwardly toward e ...


10
Michalakis Averkiou, Jeffry E Powers: Ultrasonic pulse inversion harmonic separation with reduced motional effects. ATL Ultrasound, W Brinton Yorks Jr, February 13, 2001: US06186950 (15 worldwide citation)

Pulse inversion harmonic separation is performed utilizing echoes from three or more pulses of alternating phase or polarity. Temporally different echoes of opposite phase or polarity are combined in pairs, which are in turn combined to form partial sums and a final sum in which fundamental frequenc ...