1

2

3
William H Bunnelle, Jianguo Ji, Tao Li, Jennifer M Pace, Karin R Tietje, Kathleen H Mortell, Diana L Nersesian, Michael R Schrimpf: Substituted diazabicycloalkane derivatives. Abbott Laboratories, Sreenivasarao Vepachedu, July 15, 2008: US07399765 (10 worldwide citation)

Compounds of formula (I) Z-Ar1β€”Ar2  (I) wherein Z is a diazabicyclic amine, Ar1 is a 5- or 6-membered aromatic ring, and Ar2 is selected from the group consisting of an unsubstituted or substituted 5- or 6-membered heteroaryl ring; unsubstituted or substituted bicyclic heteroaryl ring; 3,4-(methylen ...


4
Michael R Schrimpf, Diana L Nersesian, Kevin B Sippy, Jianguo Ji, Tao Li, Marc Scanio, Lei Shi, Chih Hung Lee, William H Bunnelle, Geoff G Z Zhang, Paul J Brackemeyer, Shuang Chen, Rodger F Henry: Azaadamantane derivatives and methods of use. AbbVie, Portia Chen, Antonia M Holland, November 20, 2012: US08314119 (3 worldwide citation)

The invention relates to compounds that are azaadamantane derivatives, particularly ether- or amine-substituted azaadamantane derivatives and salts and prodrugs thereof, compositions comprising such compounds, methods of using such compounds and compositions, processes for preparing such compounds, ...


5
Michael R Schrimpf, Karin R Tietje, Richard B Toupence, Jianguo Ji, Anwer Basha, William H Bunnelle, Jerome F Daanen, Jennifer M Pace, Kevin B Sippy: Diazabicyclic central nervous system active agents. Abbott Laboratories, Portia Chen, January 15, 2008: US07319106 (2 worldwide citation)

Compounds of formula I pharmaceutical compositions of these compounds, and use of said compositions to control synaptic transmission in mammals.


6
Michael R Schrimpf, Diana L Nersesian, Kevin B Sippy, Jianguo Ji, Tao Li, Lei Shi: Azaadamantane ester and carbamate derivatives and methods of use thereof. Abbott Laboratories, Lisa V Mueller, Michael Best & Friedrich, April 24, 2012: US08163916 (2 worldwide citation)

The invention relates to compounds that are substituted azaadamantane ester and carbamate derivatives, compositions comprising such compounds, and methods of using such compounds and compositions.


7
Lei Shi, William H Bunnelle, Tao Li, Marc J Scanio, Michael R Schrimpf, Chih Hung Lee: Bridgehead amine ring-fused indoles and indolines. AbbVie, Lisa V Mueller, Michael Best & Friedrich, September 3, 2013: US08524703 (2 worldwide citation)

The present application relates to indole and indoline derivatives of formula (I), formula (II), formula (III), or formula (IV) wherein a, R2, R3, h, k, m, n, L, Q, X, and Z are as defined in the specification. The present application also relates to compositions comprising such compounds, and metho ...


8
Michael R Schrimpf, Diana L Nersesian, Kevin B Sippy, Jianguo Ji, Tao Li, Marc Scanio, Lei Shi, Chih Hung Lee, William H Bunnelle, Geoff G Z Zhang, Paul J Brackemeyer, Shuang Chen, Rodger F Henry: Azaadamantane derivatives and methods of use. AbbVie, Lisa V Mueller, Michael Best & Friedrich, March 24, 2015: US08987453 (1 worldwide citation)

The invention relates to compounds that are azaadamantane derivatives, particularly ether- or amine-substituted azaadamantane derivatives and salts and prodrugs thereof, compositions comprising such compounds, methods of using such compounds and compositions, processes for preparing such compounds, ...


9
Michael R Schrimpf, Chih Hung Lee, Tao Li, Gregory A Gfesser, Kathleen H Mortell, Ramin Faghih, Diana L Nersesian, Kevin B Sippy, William H Bunnelle, Marc Scanio, Lei Shi, Murali Gopalakrishnan, Diana L Donnelly Roberts, Min Hu: Indole and indoline derivatives and methods of use thereof. AbbVie, Portia Chen, April 18, 2017: US09625475 (1 worldwide citation)

The present application relates to indole and indoline derivatives of formula (I), (II), (III), (IV), (V), or (VI) wherein a, R1, R2, R3, R4, R5, U, V, W, X, Y, and Z are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of t ...


10
Michael R Schrimpf, Chih Hung Lee, Tao Li, Gregory A Gfesser, Kathleen H Mortell, Ramin Faghih, Diana L Nersesian, Kevin B Sippy, William H Bunnelle, Marc Scanio, Lei Shi, Murali Gopalakrishnan, Diana L Donnelly Roberts, Min Hu: Indole and indoline derivatives and methods of use thereof. AbbVie, Lisa V Mueller, Michael Best & Friedrich, June 23, 2015: US09063126 (1 worldwide citation)

The present application relates to indole and indoline derivatives of formula (I), (II), (III), (IV), (V), or (VI) wherein a, R1, R2, R3, R4, R5, U, V, W, X, Y, and Z are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of t ...