1
Donna R Cody, Sheila H H DeWitt, John C Hodges, John S Kiely, Walter H Moos, Michael R Pavia, Bruce D Roth, Mel C Schroeder, Charles J Stankovic: Apparatus for multiple simultaneous synthesis. Warner Lambert Company, Charles W Almer III, Francis J Tinney, June 28, 1994: US05324483 (194 worldwide citation)

An apparatus and method which provides a suitable location for multiple, simultaneous synthesis of compounds. The apparatus consists of: a reservoir block having a plurality of wells; a plurality of reaction tubes, usually gas dispersion tubes, having filters on their lower ends; a holder block, hav ...


2
Sheila H H DeWitt, John S Kiely, Michael R Pavia, Mel C Schroeder, Charles J Stankovic: System for multiple simultaneous synthesis. Warner Lambert Company, Charles W Almer, Francis J Tinney, February 3, 1998: US05714127 (44 worldwide citation)

A system for the multiple, simultaneous synthesis of compounds preferably uses a reaction apparatus comprising a reservoir rack having a plurality of reaction wells, a plurality of reaction tubes, usually gas dispersion tubes, having filters on their lower ends, a holder block, having a plurality of ...


3
Sheila H H DeWitt, John S Kiely, Michael R Pavia, Mel C Schroeder, Charles J Stankovic: Apparatus for multiple simultaneous synthesis. Warner Lambert Company, Charles W Almer III, Francis J Tinney, January 14, 1997: US05593642 (33 worldwide citation)

An apparatus and method which provides a suitable location for multiple, simultaneous synthesis of compounds. The apparatus consists of: a reservoir block having a plurality of wells; a plurality of reaction tubes, usually gas dispersion tubes, having filters on their lower ends; a holder block, hav ...


4
Donna R Cody, Sheila H H DeWitt, John C Hodges, John S Kiely, Walter H Moos, Michael R Pavia, Bruce D Roth, Mel C Schroeder, Charles J Stankovic: Apparatus and method for multiple simultaneous synthesis. Warner Lambert Company, Francis J Tinney, Charles W Almer III, March 18, 1997: US05612002 (24 worldwide citation)

A method for the multiple, simultaneous synthesis of compounds comprising the steps of: 1) providing an apparatus comprising a plurality of reaction tubes having filter members on their lower ends, a reservoir member for receiving the filter member, a holder member having a plurality of apertures fo ...


5
Donald E Butler, Michael R Pavia, Fred M Hershenson: Benzobicyclic lactam acids and derivatives as cognition activators. Warner Lambert Company, Jerry F Janssen, April 15, 1986: US04582909 (18 worldwide citation)

Benzobicyclic lactam acids having a fused aromatic carbocyclic and a saturated lactam ring of five- or six-members, their salts, esters, and amides, are useful for reversing amnesia. Pharmaceutical compositions including these compounds, a method of preparing the compounds, and a method of treating ...


6
Sheila H H DeWitt, John S Kiely, Michael R Pavia, Mel C Schroeder, Charles J Stankovic: Apparatus for multiple simultaneous synthesis. Warner Lambert Company, Charles W Almer III, Francis J Tinney, December 10, 1996: US05582801 (9 worldwide citation)

An apparatus and method which provides a suitable location for multiple, simultaneous synthesis of compounds. The apparatus consists of: a reservoir block having a plurality of wells; a plurality of reaction tubes, usually gas dispersion tubes, having filters on their lower ends; a holder block, hav ...


7
Sheila H H DeWitt, Michael Kell, Michael R Pavia, John S Kiely, Mel C Schroeder, Charles J Stankovic, Steven Ware: Apparatus and method for multiple simultaneous synthesis. Warner Lambert Company, Charles W Almer, December 30, 1997: US05702672 (9 worldwide citation)

An apparatus for multiple, simultaneous synthesis of compounds which consists of: a reservoir block having a plurality of wells; a plurality of reaction tubes, usually gas dispersion tubes, having filters on their lower ends; a holder block, having a plurality of apertures; and a manifold, which may ...


8
David J Lauffer, Walter H Moos, Michael R Pavia, Haile Tecle, Anthony J Thomas: Oxime and amine substituted azabicyclo and azocyclo muscarinic agonists and methods of treatment. Warner Lambert Company, Michael J Atkins, April 26, 1994: US05306718 (9 worldwide citation)

Pharmaceutically useful nitrogen containing cyclic oxime and amine substituted compounds of the following general Formulas I, II and III are disclosed: ##STR1## Specifically the compounds are azabicyclo [2.2.1] omimes, azabicyclo [2.2.2] oximes, azabicyclo [2.2.1] amines, azabicyclo [2.2.2] amines, ...


9
Graham Johnson, Michael R Pavia: Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents. Warner Lambert Company, Elizabeth M Anderson, May 2, 1989: US04826860 (9 worldwide citation)

A series of substituted 2-aminobenzothiazoles and derivatives useful for treating cerebrovascular disorders are disclosed. Also disclosed is a new method for treating such disorders.


10
Donald E Butler, Fred M Hershenson, Michael R Pavia: N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids and derivatives as cognition activators. Warner Lambert Company, Jerry F Janssen, June 25, 1985: US04525476 (9 worldwide citation)

N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids, base addition salts, esters, and amides are useful as cognition activators. Pharmaceutical compositions containing these compounds and methods of using the pharmaceutical compositions for treating senility or amnesia are also disclosed.