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Benny Askew, Jeffrey Adams, Shon Booker, Guoqing Chen, Lucian V DiPietro, Daniel Elbaum, Julie Germain, Stephanie D Geuns Meyer, Gregory J Habgood, Michael Handley, Qi Huang, Tae Seong Kim, Aiwen Li, Nobuko Nishimura, Rana Nomak, Vinod F Patel, Babak Riahi, Joseph L Kim, Ning Xi, Kevin Yang, Chester Chenguang Yuan: Substituted alkylamine derivatives and methods of use. Amgen, Joseph W Bulock, April 12, 2005: US06878714 (24 worldwide citation)

Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseas ...


2
Guoqing Chen, Jeffrey Adams, Jean Bemis, Shon Booker, Guolin Cai, Lucian Di Pietro, Celia Dominguez, Daniel Elbaum, Julie Germain, Stephanie Geuns Meyer, Michael Handley, Qi Huang, Joseph L Kim, Tae Seong Kim, Alexander Kiselyov, Xiaohu Ouyang, Vinod F Patel, Leon M Smith, Markian Stec, Andrew Tasker, Ning Xi, Shimin Xu, Chester Chenguang Yuan, Michael Croghan: Substituted alkylamine derivatives and methods of use. Amgen, Joseph W Bulock, February 7, 2006: US06995162 (13 worldwide citation)

Selected heterocyclic compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis a ...


3
Daniel Elbaum, Benny C Askew Jr, Shon Booker, Julie Germain, Gregory J Habgood, Michael Handley, Tae Seong Kim, Aiwen Li, Nobuko Nishimura, Vinod F Patel, Chester Chenguang Yuan, Joseph L Kim, Guolin Cai, Guoqing Chen, Michael Croghan, Lucian V Di Pietro, Celia Dominguez, Qi Huang, Leon M Smith II, Andrew Tasker, Ning Xi, Shimin Xu: Substituted arylamine derivatives and methods of use. Amgen, Joseph W Bulock, September 5, 2006: US07101868 (8 worldwide citation)

Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment ...


4
Dominique Renwart, Michael Handley, Herman Vanormelingen: Gas turbine air intake system with bypass arrangement and methods. Donaldson Company, Merchant & Gould P C, November 20, 2007: US07297173 (7 worldwide citation)

A hopper arrangement includes a damper arrangement selectively moveable in a plurality of positions to manipulate access to the interior volume. A first position includes a standby position wherein the enclosure and the damper arrangement block access to the interior volume. Another position include ...


5
Michael Handley, Dominique Renwart, Benjamin Nichols, Herman Vanormelingen, Jimmy Vanderlinden, Timothy Sporre: Filter arrangement and methods. Donaldson Company, Merchant & Gould P C, August 27, 2013: US08518142 (3 worldwide citation)

A filter element includes a single seamless media pack having first and second opposite ends and first and second lateral sides extending between the first and second ends. The media pack also has pleats extending between the first and second ends and a first cross-section defined between the first ...


6
Celia Dominguez, Guoqing Chen, Ning Xi, Shimin Xu, Nianhe Han, Qingyian Liu, Qi Huang, Aaron Siegmund, Michael Handley, Longbin Liu, Alexander Kiselyov: Integrin inhibitors and their methods of use. Amgen, MarySusan Howard, Ron K Levy, Stuart L Watt, February 1, 2005: US06849639 (2 worldwide citation)

The invention comprises novel compounds that are effective in the prophylaxis and treatment of diseases, such as integrin receptors mediated diseases, in particular, diseases or conditions mediated by integrin receptors, such as a αvβ3, αvβ5, αvβ6, α5β1 and the like. The invention encompasses novel ...


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Michael Handley, Dominique Renwart, Benjamin Nichols, Herman Vanormelingen, Jimmy Vanderlinden, Timothy Sporre: Filter arrangement and methods. Donaldson Company, Merchant & Gould P C, July 14, 2015: US09079132

A filter element includes a single seamless media pack having first and second opposite ends and first and second lateral sides extending between the first and second ends. The media pack also has pleats extending between the first and second ends and a first cross-section defined between the first ...


9
Peter Valsler, Michael Handley, Philip Pendrill, Andrew Russell: Air intake separator systems and methods. Veotec Americas, Patterson Thuente Pederson P A, January 15, 2019: US10179305

An air intake separator system includes a plurality of vanes adapted to remove fluid or precipitation from an air stream, wherein the vanes are operably coupled to tubular rods with an interference fit. Applying an elevated temperature heat transfer fluid to the plurality of vanes removes fluid or p ...


10
Daniel Elbaum, Benny Askew, Shon Booker, Julie Germain, Gregory Habgood, Michael Handley, Tae Seong Kim, Aiwen Li, Nobuko Nishimura, Vinod F Patel, Chester Chenguang Yuan, Joseph L Kim: Substituted arylamine derivatives and methods of use. Amgen, U S Patent Operations JWB, Amgen, October 14, 2004: US20040204437-A1

Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment ...