11
Ernest J Kiser, Edward G Rice, Michael F Tomasco: Visual blood glucose concentration test strip. Lifescan, April 26, 1994: US05306623 (259 worldwide citation)

A separation matrix impregnated with a separating agent separates red blood cells or hemoglobin from whole blood. Upon separation, an impregnated test reagent reacts with the separated substantially clear component fluid to form a colored product which enables a visual or meter test for analyte leve ...


12
James Say, Michael F Tomasco, Adam Heller, Yoram Gal, Behrad Aria, Ephraim Heller, Phillip John Plante, Mark S Vreeke: Method of making a transcutaneous electrochemical sensor. TheraSense, Merchant & Gould P C, December 13, 2005: US06973706 (254 worldwide citation)

A process for the manufacture of small sensors with reproducible surfaces, including electrochemical sensors. One process includes fanning channels in the surface of a substrate and disposing a conductive material in the channels to form an electrode. The conductive material can also be formed on th ...


13
Ernest J Kiser, Edward G Rice, Michael F Tomasco: Glucose test strip for whole blood. Lifescan, May 23, 1995: US05418142 (227 worldwide citation)

A separation matrix impregnated with a separating agent separates red blood cells or hemoglobin from whole blood. Upon separation, an impregnated test reagent reacts with the separated substantially clear component fluid to form a colored product which enables a visual or meter test for glucose leve ...


14
Joel Douglas, Ernest Kiser, Michael F Tomasco, Remedios Dato, Edward G Rice, Deborah P Tuohy, Mark Maxson, Zbigniew Witko, Scott Segelke: Visually-readable reagent test strip. Lifescan, James Riesenfeld, December 1, 1998: US05843691 (201 worldwide citation)

A multilayer reagent test strip measures the concentration of analyte in a liquid sample that is applied to it. The sample is guided to a number of assay areas arrayed along the strip, where the analyte can react with a reagent to cause a color change. Each assay area also includes an inhibitor for ...


15
James L Say, Henning Sakslund, Michael F Tomasco: Sensor for measuring a bioanalyte such as lactate. Pepex Biomedical L L C, Merchant & Gould P C, October 15, 2002: US06464849 (187 worldwide citation)

The present disclosure relates to a sensor including a bundle of electrically conductive fibers. The sensor also includes a sensing material coating at least some of the fibers in the bundle, and an insulating layer that surrounds the bundle of electrically conductive fibers.


16
Michael F Tomasco, Maria Teodorczyk, Remedios Dato, Edward G Rice: Blood glucose strip having reduced side reactions. LifeScan, James Riesenfeld, April 15, 1997: US05620863 (176 worldwide citation)

A reagent strip for measuring glucose concentration in a biological fluid containing red blood cells has reduced interference of hematocrit with the glucose measurement. When a biological fluid contacts the strip, it causes, in a reagent impregnated in the strip, a color change which is a measure of ...


17
James L Say, Henning Sakslund, Michael F Tomasco, Jay D Audett, Hyun Cho, Duane O Yamasaki, Adam Heller: Mass transport limited in vivo analyte sensor. TheraSense, Merchant & Gould P C, December 13, 2005: US06975893 (167 worldwide citation)

An in vivo electrochemical sensor including a working electrode, and an analyte-responsive sensing layer proximate the working electrode. The sensing layer is exposed at an edge of the sensor, wherein the sensor signal is limited, at least in part, by mass transport of analyte to the sensing layer. ...


18
Ernest J Kiser, Michael F Tomasco, Edward G Rice, Yeung S Yu: Chemical timer for a visual test strip. Lifescan, James Riesenfeld, February 17, 1998: US05719034 (126 worldwide citation)

A chemical timer for a direct-reading reagent test strip changes color a predetermined time after a biological fluid is applied to the strip. The strip measures the concentration of an analyte in the fluid. The timer is a dry coating of an indicator, an enzyme-containing reagent that when hydrated c ...


19
James Say, Michael F Tomasco, Adam Heller, Yoram Gal, Behrad Aria, Ephraim Heller, Phillip John Plante, Mark S Vreeke, Keith A Friedman, Fredric C Colman: Analyte monitoring device and methods of use. Abbott Diabetes Care, Jackson & Co, January 15, 2013: US08353829 (59 worldwide citation)

An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing ...


20
James Say, Michael F Tomasco, Adam Heller, Yoram Gal, Aria Behrad, Ephraim Heller, Phillip John Plante, Mark S Vreeke, Keith A Friedman, Fredric C Colman: Analyte monitoring device and methods of use. Abbott Diabetes Care, Jackson & Co, December 28, 2010: US07860544 (29 worldwide citation)

An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing ...



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