1
John Bridgham, Kevin Corcoran, George Golda, Michael C Pallas, Sydney Brenner: Planar arrays of microparticle-bound polynucleotides. Lynx Therapeutics, Stephen C Macevicz, LeeAnn Gorthey, June 18, 2002: US06406848 (233 worldwide citation)

An apparatus and system are provided for simultaneously analyzing a plurality of analytes anchored to microparticles. Microparticles each having a uniform population of a single kind of analyte attached are disposed as a substantially immobilized planar array inside of a flow chamber where steps of ...


2
John Bridgham, Kevin Corcoran, George Golda, Sydney Brenner, Michael C Pallas: System and apparatus for sequential processing of analytes. Solexa, Vincent M Powers, Lee Ann Gorthey, Perkins Coie, November 29, 2005: US06969488 (208 worldwide citation)

An apparatus and system are provided for simultaneously analyzing a plurality of analytes anchored to microparticles. Microparticles each having a uniform population of a single kind of analyte attached are disposed as a substantially immobilized planar array inside of a flow chamber where steps of ...


3
Glenn Albrecht, Sydney Brenner, Robert B DuBridge, David H Lloyd, Michael C Pallas: Massively parallel signature sequencing by ligation of encoded adaptors. Lynx Therapeutics, Stephen C Macevicz, January 11, 2000: US06013445 (197 worldwide citation)

The invention provides a method of nucleic acid sequence analysis based on the ligation of one or more sets of encoded adaptors to the terminus of a target polynucleotide. Encoded adaptors whose protruding strands form perfectly matched duplexes with the complementary protruding strands of the targe ...


4
John Bridgham, Kevin Corcoran, George Golda, Michael C Pallas, Sydney Brenner: System and apparatus for sequential processing of analytes. Lynx Therapeutics, Stephen C Macevicz, Vincent M Powers, LeeAnn Gorthey, November 25, 2003: US06654505 (159 worldwide citation)

An apparatus and system are provided for simultaneously analyzing a plurality of analytes anchored to microparticles. Microparticles each having a uniform population of a single kind of analyte attached are disposed as a substantially immobilized planar array inside a flow chamber where steps of an ...


5
John Bridgham, Kevin P Corcoran, George S Golda, Michael C Pallas, Sydney Brenner: Planar arrays of microparticle-bound polynucleotides. Lynx Therapeutics, Vincent M Powers, Lee Ann Gorthey, Perkins Coie, October 19, 2004: US06806052 (151 worldwide citation)

An apparatus and system are provided for simultaneously analyzing a plurality of analytes anchored to microparticles. Microparticles each having a uniform population of a single kind of analyte attached are disposed as a substantially immobilized planar array inside of a flow chamber where steps of ...


6
John Bridgham, Kevin Corcoran, George Golda, Michael C Pallas, Sydney Brenner: System and apparatus for sequential processing of analytes. Solexa, LeeAnn Gorthey, Perkins Coie, October 16, 2007: US07282370 (148 worldwide citation)

An apparatus and system are provided for simultaneously analyzing a plurality of analytes anchored to microparticles. Microparticles each having a uniform population of a single kind of analyte attached are disposed as a substantially immobilized planar array inside of a flow chamber where steps of ...


7
John Bridgham, Kevin Corcoran, George Golda, Michael C Pallas, Sydney Brenner: System and apparatus for sequential processing of analytes. Lynx Therapeutics, Vincent M Powers, Lee Ann Gorthey, Perkins Coie, December 14, 2004: US06831994 (131 worldwide citation)

An apparatus and system are provided for simultaneously analyzing a plurality of analytes anchored to microparticles. Microparticles each having a uniform population of a single kind of analyte attached are disposed as a substantially immobilized planar array inside of a flow chamber where steps of ...


8
John Bridgham, Kevin Corcoran, George Golda, Michael C Pallas, Sydney Brenner: System and apparatus for sequential processing of analytes. Illumina, Knobbe Martens Olson & Bear, January 29, 2013: US08361713 (41 worldwide citation)

An apparatus and system are provided for simultaneously analyzing a plurality of analytes anchored to microparticles. Microparticles each having a uniform population of a single kind of analyte attached are disposed as a substantially immobilized planar array inside of a flow chamber where steps of ...


9
Patrick D Kinney, Howard G King, Michael C Pallas, Mark Naley: Methods, software, and apparatus for focusing an optical system using computer image analysis. Applera Corporation, July 1, 2008: US07394943 (15 worldwide citation)

Methods, software, and apparatus for focusing an image in biological instrument are disclosed. Focusing elements are moved to various focus positions within a focus element travel range, and sample images are captured at the various focus positions. The sample images are resolved into subregions and ...


10
Glenn Albrecht, Sydney Brenner, Robert B DuBridge, David H Lloyd, Michael C Pallas: Massively parallel signature sequencing by ligation of encoded adaptors. Illumina, Reinhart Boerner Van Deuren s c, January 10, 2012: USRE043097

The invention provides a method of nucleic acid sequence analysis based on the ligation of one or more sets of encoded adaptors to the terminus of a target polynucleotide. Encoded adaptors whose protruding strands form perfectly matched duplexes with the complementary protruding strands of the targe ...