1
Mccarthy Jeanette, Ableson Alan: Diagnosis and treatment of vascular disease. Vitivity, Mccarthy Jeanette, Ableson Alan, SMITH DeAnn F, February 27, 2003: WO/2003/016494 (3 worldwide citation)

The present invention is based at least in part on the discovery of polymorphisms within the integrin beta 3 (ITGB3), von Willebrand factor (VWF), endothelin receptor type B (EDNRB), factor 2 (F2), P-selectin (SELP), thrombospondin 1 (THBS1), and thrombospondin 2 (THBS2) genes. Accordingly, the inve ...


2
Lander Eric S, Gargill Michele, Ireland James S, Bolk Stacey, Daley George Q, Mccarthy Jeanette J: Single nucleotide polymorphisms in genes. Whitehead Institute For Biomedical Research, Millennium Pharmaceuticals, TREANNIE Lisa M, March 15, 2001: WO/2001/018250

The invention provides nucleic acid segments of the human genome, particularly nucleic acid segments from a gene, including polymorphic sites. Allele-specific primers and probes hybridizing to regions flanking or containing these sites are also provided. The nucleic acids, primers and probes are use ...


3
Mccarthy Jeanette: Diagnosis and treatment of vascular disease. Vitivity, Mccarthy Jeanette, SMITH DeAnn F, March 13, 2003: WO/2003/020118

The present invention is based at least in part on the discovery of polymorphisms within the thrombospondin 2 (THBS2) gene, the angiotensin converting enzyme 1 (ACE), and the beta fibrinogen (FGB) gene. Accordingly, the invention provides nucleic acid molecules having a nucleotide sequence of an all ...


4
Mccarthy Jeanette, Daley George, Bolk Stacey: Diagnosis and treatment of vascular disease. Vitivity, Whitehead Institute For Biomedical Research, Mccarthy Jeanette, Daley George, Bolk Stacey, SMITH DeAnn F, March 13, 2003: WO/2003/020120

The present invention is based at least in part on the discovery of polymorphisms within the thrombospondin 1(THBS1) and thrombospondin 4 (THBS4) genes. Accordingly, the invention provides nucleic acid molecules having a nucleotide sequence of an allelic variant of a THBS1 or THBS4 gene. The inventi ...


5
Mccarthy Jeanette: Diagnosis and treatment of vascular disease. Vitivity, Mccarthy Jeanette, SMITH DeAnn F, January 30, 2003: WO/2003/007801

The present invention is based at least in part on the discovery of polymorphisms within the phospholipase C gamma 1 (PLCG1) gene and the plasminogen activator inhibitor type 2 (PAI-2) gene. Accordingly, the invention provides nucleic acid molecules having a nucleotide sequence of an allelic variant ...


6
Mccarthy Jeanette: Diagnosis and treatment of vascular disease. Vitivity, Mccarthy Jeanette, SMITH DeAnn F, October 30, 2003: WO/2003/089897

The present invention is based at least in part on the discovery of polymorphisms within the Factor VII (F7) gene. Accordingly, the invention provides nucleic acid molecules having a nucleotide sequence of an allelic variant of an F7 gene. The invention also provides methods for identifying specific ...


7
Mccarthy Jeanette: Diagnosis and treatment of vascular disease. Vitivity, Mccarthy Jeanette, SMITH DeAnn F, April 10, 2003: WO/2003/029493

The present invention is based at least in part on the discovery of polymorphisms within the Factor 2 (F2)gene. Accordingly, the invention provides nucleic acid molecules having a nucleotide sequence of an allelic variant of an F2 gene. The invention also provides methods for identifying specific al ...


8
Mccarthy Jeanette: Diagnosis and treatment of vascular disease. Vitivity, Mccarthy Jeanette, SMITH DeAnn F, April 3, 2003: WO/2003/026488

The present invention is based at least in part on the discovery of a polymorphism within the interleukin 1 receptor antagonist (IL1RN) gene. Accordingly, the invention provides nucleic acid molecules having a nucleotide sequence of an allelic variant of an IL1RN gene. The invention also provides me ...


9
Lander Eric S, Gargill Michele, Ireland James S, Bolk Stacey, Daley George Q, Mccarthy Jeanette J: Single nucleotide polymorphisms in genes. Whitehead Biomedical Inst, Millennium Pharm, September 18, 2002: EP1240354-A2

The invention provides nucleic acid segments of the human genome, particularly nucleic acid segments from a gene, including polymorphic sites. Allele-specific primers and probes hybridizing to regions flanking or containing these sites are also provided. The nucleic acids, primers and probes are use ...