1
David B Fenske, Pieter R Cullis, Kim Wong, Maurer Norbert, Johanna M Leenhouts, Elisabeth Maurer, Nancy Boman: Ionophore-mediated liposome loading. University of British Columbia, Townsend and Townsend and Crew, November 17, 1998: US05837282 (46 worldwide citation)

Novel methods are provided for loading a weakly basic drug into liposomes utilizing an electoneutral transport system. In these methods, ionophores are utilized with liposomes having a metal ion gradient to facilitate the exchange of metal ions for protons. The transported metal ion will, in some em ...


2
Wolf Michael, Muenkel Karlheinz, Stinzendoerfer Joachim, Bauder Ralf, Maurer Norbert: Filter sytem for liquids. Mann & Hummel, August 16, 2006: EP1690581-A1 (4 worldwide citation)

A filter outer casing has a first set of interlocking formations around its outer circumference and/or its lower edge. Each formation is interrupted by a recess with axial extent. Alternatively the recess is adjacent to the side of the formation. The filter element (19) has a fluid-tight casing (16) ...


3
Cullis Peter, Bally Marcel, Ciufolini Marco, Maurer Norbert: Modified drugs for use in liposomal nanoparticles. The University Of British Columbia, Cullis Peter, Bally Marcel, Ciufolini Marco, Maurer Norbert, November 26, 2009: WO/2009/141738 (1 worldwide citation)

Drag derivatives are provided herein which are suitable for loading into liposomal nanoparticle carriers. In some preferred aspects, the derivatives comprise a poorly water-soluble drag derivatized with a weak-base moiety that facilitates active loading of the drag through a LN transmembrane pH or i ...


4
Cullis Pieter R, Madden Thomas D, Hope Michael J, Ansell Steven M, Mui Barbara Ls, Semple Sean C, Maurer Norbert: Liposomal formulations comprising dihydrosphingomyelin and methods of use thereof. Inex Pharmaceuticals Corporation, Hermanns Karl R, Cullis Pieter R, Madden Thomas D, Hope Michael J, Ansell Steven M, Mui Barbara Ls, Semple Sean C, Maurer Norbert, LAHERTY Carol D, December 22, 2005: WO/2005/120461 (1 worldwide citation)

The present invention includes novel liposomes comprising dihydrosphingomyelin. The invention also includes compositions comprising these liposomes and a therapeutic agent, in addition to methods and kits for delivering a therapeutic agent or treating a disease, e.g., a cancer, using these compositi ...


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Fenske David B, Cullis Pieter R, Wong Kim, Maurer Norbert, Leenhouts Johanna Maria, Maurer Elisabeth, Boman Nancy: Chargement de medicaments faiblement basiques dans des liposomes par le biais dionophores, Ionophore-mediated liposome loading of weakly basic drug. The University Of British Columbia, The University Of British Columbia, FETHERSTONHAUGH & CO, May 7, 1998: CA2269921

Novel methods are provided for loading a weakly basic drug into liposomes utilizing an electroneutral transport system. In these methods, ionophores are utilized with liposomes having a metal ion gradient to facilitate the exchange of metal ions for protons. The transported metal ion will, in some e ...


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Cullis Pieter R, Madden Thomas D, Hope Michael J, Ansell Steven M, Mui Barbara L S, Semple Sean C, Maurer Norbert: Liposomal formulations comprising dihydrosphingomyelin and methods of use thereof. Inex Pharmaceuticals, February 14, 2007: EP1750673-A2

The present invention includes novel liposomes comprising dihydrosphingomyelin. The invention also includes compositions comprising these liposomes and a therapeutic agent, in addition to methods and kits for delivering a therapeutic agent or treating a disease, e.g., a cancer, using these compositi ...


9
Maurer Norbert, Wong Kim F, Cullis Pieter R: Methods for preparation of lipid-encapsulated therapeutic agents. Inex Pharmaceuticals, Maurer Norbert, Wong Kim F, Cullis Pieter R, KINGWELL Brian G, January 25, 2001: WO/2001/005374

Fully lipid-encapsulated therapeutic agent particles of a charged therapeutic agent are prepared by combining a lipid composition containing preformed lipid vesicles, a charged therapeutic agent, and a destabilizing agent to form a mixture of preformed vesicles and therapeutic agent in a destabilizi ...


10
Maurer Norbert, Kontny Horst, Binger Bernhard: Braking system for full-track vehicles. Zahnradfabrik Friedrichshafen, Maurer Norbert, Kontny Horst, Binger Bernhard, RAUE Reimund, September 22, 1988: WO/1988/006990

Braking system for full-track vehicles, with a gear mechanism (3) and a differential steering mechanism (8), both disposed transversally to the longitudinal axis (F) of the vehicle, and two summing mechanisms (5) disposed in the vicinity of the two gear output shafts (54). The gear mechanism and the ...