1
Matsuo Masaaki, Hagiwara Daijiro, Miyake Hiroshi: Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same.. Fujisawa Pharmaceutical Co, October 31, 1990: EP0394989-A2 (93 worldwide citation)

A compound of the formula : wherein R is lower alkyl, aryl, arylamino, pyridyl, pyrrolyl, pyrazolopyridyl, quinolyl, or a group of the formula : wherein the symbol of a line and dotted line is a single bond or a double bond, X is CH or N, and Z is O, S or NH, each of which may have suitable substitu ...


2
Matsuo Masaaki, Tsuji Kiyoshi, Konishi Nobukiyo, Nakamura Katsuya: Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same.. Fujisawa Pharmaceutical Co, March 27, 1991: EP0418845-A1 (82 worldwide citation)

A compound of the formula : wherein R is aryl which may be substituted with substituent(s) selected from the group consisting of lower alkyl, halogen, lower alkoxy, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, hydroxy, lower alkylsulfonyloxy, nitro, amino, lower alkylamino, acylamino a ...


3
Matsuo Masaaki, Hagiwara Daijiro, Miyake Hiroshi: Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same.. Fujisawa Pharmaceutical Co, September 20, 1989: EP0333174-A2 (69 worldwide citation)

A compound of the formula : R-A-D-Trp(R)-Phe-R wherein R is hydrogen or an amino protective group, R is hydrogen, an amino protective group, carbamoyl(lower)alkyl, carboxy(lower)alkyl or protected carboxy(lower)alkyl, R is ar(lower)alkyl, a group of the formula: wherein R and R are each hydrogen, ar ...


4
Matsuo Masaaki, Tsuji Kiyoshi, Ogino Takashi, Konishi Nobukiyo: Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity.. Fujisawa Pharmaceutical Co, August 11, 1993: EP0554829-A2 (62 worldwide citation)

A compound of the formula : wherein R is aryl which is substituted with substituent(s) selected from the group consisting of lower alkylthio, cyclo(lower)alkyl, hydroxy, hydroxy(lower)alkyl, cyano, lower alkylenedioxy, acyl, acyloxy, aryloxy and lower alkoxy optionally substituted with acyl or lower ...


5
Matsuo Masaaki, Hagiwara Daijiro, Manabe Takashi, Nobukiyo Konishi, Shigenaga Shinji, Murano Kenji, Matsuda Hiroshi, Miyake Hiroshi: Piperazine derivatives as tachykinin antagonists.. Fujisawa Pharmaceutical Co, May 31, 1995: EP0655442-A1 (56 worldwide citation)

A compound of the following general formula : wherein X is carbonyl or sulfonyl; Y is bond or lower alkylene; R is halogen, lower alkyl, halo(lower)alkyl, aryloxy, nitro or amino which may have 1 or 2 and same or different substituent(s) selected from lower alkyl, acyl and lower alkanesulfonyl; R is ...


6
Ueda Ikuo, Matsuo Masaaki, Satoh Susumu, Watanabe Takao: 2-oxo-benzothiazoline, benzoxazoline or indoline derivatives, their preparation, and pharmaceutical compositions comprising such derivatives.. Fujisawa Pharmaceutical Co, January 14, 1981: EP0022317-A1 (55 worldwide citation)

Compounds having the formula: wherein R1_ is hydroxy, halogen, nitro, amino, cycloalkyl having from 3 to 8 carbon atoms, aryl or aryloxy which may be substituted with halogen, R is hydrogen, halogen or lower alkyl, R is carboxy or protected carboxy, Ya is sulfur, oxygen or methylene, and A is lower ...


7
Matsuo Masaaki, Ogino Takashi, Igari Norihiro, Seno Hachiro, Shimomura Kyoichi: Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same.. Fujisawa Pharmaceutical Co, February 13, 1991: EP0412404-A2 (47 worldwide citation)

A compound of the formula : wherein R is hydrogen or acyl which may be substituted with halogen, R is hydrogen, lower alkyl, hydroxy(lower)alkyl, halogen or carboxy, A is -CH2-, -CO-, -C(=NOR)- [wherein R is lower alkyl, [wherein m is 0, 1 or 2], and R is aryl which may be substituted with halogen, ...


8
Matsuo Masaaki, Hagiwara Daijiro, Miyake Hiroshi: Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same.. Fujisawa Pharmaceutical Co, April 29, 1992: EP0482539-A2 (46 worldwide citation)

A compound of the formula : wherein R is lower alkyl, aryl, arylamino, pyridyl, pyrrolyl, pyrazolopyridyl, quinolyl, or a group of the formula : wherein the symbol of a line and dotted line is a single bond or a double bond, X is CH or N, and Z is O, S or NH, each of which may have suitable substitu ...


9
Matsuo Masaaki, Hagiwara Daijiro, Miyake Hiroshi: Peptide compound.. Fujisawa Pharmaceutical Co, December 2, 1992: EP0515681-A1 (26 worldwide citation)

A tachykinin-antagonistic compound of the following general formula and its salt: R-A-D-Trp(R)-A-R, wherein R represents hydrogen or an amino protective group, R represents an amino protective group, R represents an aryl-lower alkoxy, N-(lower) alkyl, or N-(lower) alkyl amino group, A represents a s ...


10
Ueda Ukuo, Matsuo Masaaki, Taniguchi Kiyoshi, Katsura Yousuke: 2-imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same.. Fujisawa Pharmaceutical Co, October 15, 1980: EP0017484-A1 (23 worldwide citation)

Compounds of the general formula: wherein R is aryl which may have 1 to 5 substituent(s) selected from the groups consisting of halogen, lower alkyl, lower alkoxy, lower alkanesulfonamido, mono(or di or tri)-halo(lower)alkyl, carbomoyl, hydroxy, nitro, amino, cyano, sulfamoyl, N,N-di(lower)alkylsulf ...