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Taniguchi Tadatsugu, Muramatsu Masami, Sugano Haruo, Matsui Hiroshi, Kashima Nobukazu, Hamuro Junji: Interleukin-2 polypeptides.. Ajinomoto, Japan Found Cancer, September 19, 1984: EP0118617-A2 (38 worldwide citation)

Interleukin-2 polypeptides, which are free from substances produced by human cells, are provided. These interleukin-2 polypeptides are produced by a culture of cells of Escherichia coli, constructed by gene-recombination technique, into which a plasmid comprising the genetic information for the synt ...


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Kishimoto Tadamitsu, Hirano Toshio, Matsui Hiroshi, Takahara Yoshiyuki, Akiyama Yukio, Okano Akira: Recombinant b-cell differentiation factor.. Ajinomoto, Kishimoto Tadamitsu, March 2, 1988: EP0257406-A2 (36 worldwide citation)

A purified human B-cell differentiation factor (BCDF) which does not have a natural signal peptide attached to the N-terminal thereof, DNA encoding the BCDF, transformed cells containing such DNA, a process for producing and obtaining the BCDF, and compositions containing the BCDF are disclosed.


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Uchikawa Akira, Iwasaki Atsushi, Fukuoka Toshio, Matsui Hiroshi, Matsumura Mitsuo, Sato Yasuhiko, Aoyama Masaaki, Shinomiya Eiichi, Fujinoki Akira, Ogino Nobuyoshi: Manufacture of a quartz glass vessel for the growth of single crystal semiconductor.. Shinetsu Handotai, Shinetsu Quartz Prod, June 7, 1989: EP0319031-A2 (21 worldwide citation)

A quartz glass crucible adapted for use in a process for pulling a single crystal semiconductor material having an opaque outer substrate of a quartz glass with a relatively high bubble content and an inner transparent glass layer which is substantially free from bubbles. The crucible is produced wh ...


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Matsumura Mitsuo, Matsui Hiroshi: Manufacture of quartz glass crucible for use in the manufacture of single crystal in silicon.. Shinetsu Quartz Prod, January 2, 1992: EP0463543-A1 (18 worldwide citation)

A quartz glass crucible for use in a process for pulling a single crystal silicon and having an outer layer (3) and an inner layer (4). The outer layer (3) contains less than 0.3 ppm each of Na, K and Li and more than 5 ppm of Al. The outer layer (3) further contains bubbles to present an opaque app ...


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Taniguchi Tadatsugu, Matsui Hiroshi, Hamuro Junji, Sato Takaaki, Sano Konosuke: Saccharomyces cerevisiae possessing gene coding for interleukin-2 polypeptide and method for producing interleukin-2 using the yeast.. Ajinomoto, Japan Found Cancer, May 22, 1985: EP0142268-A1 (18 worldwide citation)

There is disolved a cell of Saccharomyces cerevisiae transformed with a recontinant DNA comprising a gene coding for a polypeptide possessing the activity of interleukin-2 and a vector DNA capable of propagating in said cell, the coding sequence of said gene being located at a position downstream of ...


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Murakami Tsutomu, Ozaki Hirochika, Oketani Naohiro, Morishita Akira, Matsui Hiroshi, Takahashi Takeshi, Adachi Katsumi, Takizawa Takushi, Asao Yoshito, Ohashi Atsushi: Winding assembly for dynamo electric machine, manufacturing method therefor, and stator for dynamo electric machine therewith. Mitsubishi Electric, June 21, 2002: JP2002-176752 (18 worldwide citation)

PROBLEM TO BE SOLVED: To provide a winding for a dynamo electric machine capable of improving mass production and downsizing.SOLUTION: This winding assembly for dynamo electric machine is composed of a plurality of winding assemblies attached to iron core slots. The respective winding assemblies 14 ...


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Tonouchi Naoto Central Res Lab, Kojima Hiroyuki Central Res La, Matsui Hiroshi Central Res Lab: Recombinant dna sequences encoding feedback inhibition released enzymes, plasmids comprising the recombinant dna sequences, transformed microorganisms useful in the production of aromatic amino acids, and a process for preparing aromatic amino acids by fermentation.. Ajinomoto, June 3, 1992: EP0488424-A2 (17 worldwide citation)

A method for releasing feedback inhibition of the key enzymes in the production of aromatic amino acids by fermentation is disclosed. Aromatic amino acids are prepared by a process which comprises transforming a microorganism with a recombinant DNA sequence bearing a gene or gene group encoding a fe ...


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Hashiguchi Ken Ichi C O Centra, Kishino Hiroko C O Central Res, Tsujimoto Nobuharu C O Central, Matsui Hiroshi C O Central Res: L-isoleucine producing bacterium and method for preparing l-isoleucine through fermentation.. Ajinomoto, December 6, 1995: EP0685555-A1 (17 worldwide citation)

An L-isoleucine-producing bacterium belonging to the genus Escherichia which carries a thrABC operon which comprises a thrA gene coding for aspartokinase I-homoserine dehydrogenase I substantially released from the inhibition by L-threonine and an ilvGMEDA operon which comprises an ilvA gene coding ...


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Takagi Hiroshi, Arafuka Shino, Matsui Hiroshi, Washizu Kinya, Ando Keiichi, Koikeda Satoshi: Recombinant transglutaminase.. Amano Pharma, Ajinomoto, April 22, 1992: EP0481504-A1 (16 worldwide citation)

A DNA gene which encodes transglutaminase, a plasmid in which the DNA gene is incorporated, a transformant transformed with the plasmid and a process for the production of transglutaminase that comprises culturing the transformant.