1
Yasuharu Noishiki, Kazuhiko Kodaira, Masayasu Furuse, Teruo Miyata: Method of preparing antithrombogenic medical materials. Koken, Armstrong Nikaido Marmelstein & Kubovcik, February 21, 1989: US04806595 (97 worldwide citation)

In a method of preparing an antithrombogenic medical material having a heparinized collagen as an antithrombogenic component, there is provided a method comprising the steps of fixing a protamine to a collagen through a polyepoxy compound, and heparinizing the collagen by fixing heparin to the prota ...


2
Teruo Miyata, Taichiro Akiyama, Masayasu Furuse: Artificial bone. Koken, Edward J Mahler, February 9, 1982: US04314380 (83 worldwide citation)

Artificial bone is prepared from animal bone treated for removal of organics, burned, baked and immersed in atelocollagen solution.


3
Teruo Miyata, Kazuhiko Kodaira, Masayasu Furuse, Yasuharu Noishiki: Hemostatic agent composed of collagen/gelatin and protamine. Koken, Sherman and Shalloway, June 7, 1988: US04749689 (74 worldwide citation)

This invention relates to a hemostatic agent used in surgical operations, which can be produced in two ways: one blending collagen/gelatin with protamine, the other blending collagen/gelatin with protamine and a bi-functional cross-linking agent so as to make said collagen/gelatin have a covalent bo ...


4
Eisaburo Imamura, Yasuharu Noishiki, Hitoshi Koyanagi, Teruo Miyata, Masayasu Furuse: Bioprosthetic valve. Koken, Varndell Legal Group, January 14, 1992: US05080670 (62 worldwide citation)

A bioprosthetic valve made from a biological tissue containing collagen which has been cross-linked with a polyepoxy compound is disclosed. The valve has excellent biocompatibility and is durable and is free from calcification.


5
Makoto Tsunenaga, Naoki Tominaga, Toshio Nishiyama, Toru Yamashita, Mutsumi Fukuyama, Teruo Miyata, Masayasu Furuse: Hyaluronic acid-containing aqueous solution or aqueous dispersion of collagen. Shiseido, Koken, Varndell Legal Group, August 11, 1992: US05137875 (39 worldwide citation)

A hyaluronic acid-containing aqueous solution or aqueous dispersion of collagen having a pH of from about 6.5 to about 8.0 and an osmolality of from about 230 to about 320 mOsm/kgH.sub.2 O. The aqueous solution or the aqueous dispersion of collagen is useful as an agent for correction and reparation ...


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Yasuharu Noishiki, Kazuhiko Kodaira, Masayasu Furuse, Teruo Miyata, Takeaki Miyamoto, Hiraku Ito: Production process of an antithrombogenic and antiadhesive material for medical use. Koken Company, Sherman and Shalloway, September 1, 1987: US04690973 (10 worldwide citation)

This invention concerns a production process of an antithrombogenic and antiadhesive material which can favorably be used as artificial blood vessels, artificial valves, grafting patches for cardiovascular organs, artificial heart catheters and so on. The gist of this invention is constructed substa ...


8
Keiji Fujioka, Shigeji Sato, Yoshio Sasaki, Hiromi Naito, Teruo Miyata, Masayasu Furuse: Method for drying wetted molded product. Sumitomo Pharmaceuticals Company, Koken, Birch Stewart Kolasch & Birch, November 17, 1992: US05164139 (4 worldwide citation)

A method for drying a wetted molded product of pasty high viscous composition which comprises subjecting the molded product to a dehydration process while wholly or partially contacting the product with an open-cell foamed hydrophobic porous membrane.


9
Tetsuro Namiki, Masayasu Furuse, Yoshimitsu Kuroyanagi, Teruo Miyata: Surfactant composed of acylated collagen or acylated gelatine and a production process thereof. Koken, Sherman and Shalloway, December 22, 1987: US04714758 (1 worldwide citation)

This invention relates to a surfactant composed of acylated collagen or acylated gelatine produced by the acylation of the side chain amino radicals of collagen or gelatine with an aliphatic acid having 2-26 carbon atoms and a dicarboxylic acid having 2-8 carbon atoms and a production process thereo ...


10
Tetsuro Namiki, Masayasu Furuse, Yoshimitsu Kuroyanagi, Teruo Miyata, Takashi Suzuki: Surfactant composed of acylated collagen or acylated gelatine and a production process thereof. Koken, Shiseido, Sherman and Shalloway, June 20, 1989: US04840937

This invention relates to a surfactant with less toxicity and irritation against the human body and a production process thereof. The surfactant is produced by the acylation of the side chain amino radicals of collagen or gelatine with an aliphatic acid having 2 to 26 carbon atoms; it is used as an ...