1
Yoshihiro Ashihara, Isao Nishizono, Hidetaka Minakawa, Masahisa Okada, Yasusuke Sakurabayashi, Fumio Watanabe, Shin ichi Wakana: Automatic immunological measuring system. Fujirebio, Sughrue Mion Zinn Macpeak and Seas, October 27, 1992: US05158895 (120 worldwide citation)

An automatic immunoassay apparatus utilizes cartridges each having at least two wells, a first well containing solid phase material carrying antigen or antibody, and a second well containing antibody or antigen labelled with labelling compound. The wells may be sealed with a suitable sealing film be ...


2
Yoshihiro Ashihara, Isao Nishizono, Hidetaka Minakawa, Masahisa Okada, Yasusuke Sakurabayashi, Fumio Watanabe, Shin ichi Wakana: Automatic immunological measuring system. January 9, 1996: US05482839 (68 worldwide citation)

An automatic immunoassay apparatus utilizes cartridges each having at least two wells, a first well of said wells containing solid phase material carrying antigen or antibody, a second well of said wells containing antibody or antigen labelled with labelling compound. The wells may be sealed with a ...


3
Masahisa Okada, Yoshihiro Ashihara, Akira Yano, Masao Oishi, Katsuaki Yoshioka, Toshiomi Nakamura: Immunoassay using magnetic particle. Fujirebio, Nippon Paint, Jordan and Hamburg, June 14, 1994: US05320944 (33 worldwide citation)

An immunoassay method using magnetic particles comprising a core and a coating layer on the surface thereof, The core comprises an organic polymer and the coating layer comprises an iron oxide type ferrite coating layer. An antigen or an antibody is bound onto the surface of the coating layer and th ...


4
Motohiro Sasaki, Masahiko Matsukawa, Katsuaki Yoshioka, Makoto Anan, Mitsuo Isomura, Yoshihiro Ashihara, Masahisa Okada: Magnetic particle and immunoassay using the same. Nippon Paint, Fujirebio, Jordan and Hamburg, April 7, 1998: US05736349 (32 worldwide citation)

There are disclosed a magnetic particle for an immunoassay method, which comprises a core and a coating layer formed on the surface of the core wherein said core comprises an organic polymer matrix and said coating layer comprises a mixed crystal ferrite represented by the formula:


5
Yoshihiro Ashihara, Isao Nishizono, Hidetaka Minakawa, Masahisa Okada, Yasusuke Sakurabayashi, Fumio Watanabe, Shin ichi Wakana: Method of immunoassay measurement. Fujirebio, Cooper & Dunham, March 1, 1994: US05290708 (24 worldwide citation)

An automatic immunoassay apparatus utilizes cartridges each having at least two wells, a first well containing solid phase material carrying antigen or antibody, and a second well containing antibody or antigen labelled with labelling compound. The wells may be sealed with a suitable sealing film be ...


6
Masahisa Okada, Yoshihiro Ashihara, Tadashi Ninomiya, Akira Yano: Chemiluminescence assays using stabilized dioxetane derivatives. Fujirebio, Oblon Spivak McClelland Maier & Neustadt, March 10, 1992: US05094939 (24 worldwide citation)

A multi-pH chemiluminescence-based assay method comprising first-stage light production by the activation by cleavage of a phosphatase cleavable dioxetane derivative within a pH range optimal for enzyme catalysis, followed by the second-stage generation of increased light energy from the products of ...


7
Birger Blomback, Masahisa Okada: Fibrin gel-containing filter of porous material. New York Blood Center, Sprung Horn Kramer & Woods, March 19, 1985: US04505817 (14 worldwide citation)

There is disclosed a filter comprising fibrin in gel form, the gel having substantially uniform pore sizes, and the filter comprising means for retaining the shape of at least one surface of the gel against deformation when contacted by a flowing medium.


8
Birger Blomback, Masahisa Okada: Fibrin gel-containing filter. New York Blood Center, Sprung Horn Kramer & Woods, February 3, 1987: US04640778 (12 worldwide citation)

There is disclosed a filter comprising fibrin in gel form, the gel having substantially uniform pore sizes, and the filter comprising means for retaining the shape of at least one surface of the gel against deformation when contacted by a flowing medium.


9
Birger Blomback, Masahisa Okada: Fibrin gel. New York Blood Center, Sprung Horn Kramer & Woods, May 6, 1986: US04587018 (11 worldwide citation)

There is disclosed a filter comprising fibrin in gel form, the gel having substantially uniform pore sizes, and the filter comprising means for retaining the shape of at least one surface of the gel against deformation when contacted by a flowing medium.


10
Birger Blomback, Masahisa Okada: Process for separating substances from one another using a fibrin gel filter. New York Blood Center, Sprung Horn Kramer & Woods, March 19, 1985: US04505822 (8 worldwide citation)

There is disclosed a filter comprising fibrin in gel form, the gel having substantially uniform pore sizes, and the filter comprising means for retaining the shape of at least one surface of the gel against deformation when contacted by a flowing medium.