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Masaaki Matsuo, Kiyoshi Tsuji, Nobukiyo Konishi, Katsuya Nakamura: Pyrazole derivatives, and pharmaceutical composition comprising the same. Fujisawa Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt, July 28, 1992: US05134142 (104 worldwide citation)

The present invention concerns pyrazole derivatives of formula: ##STR1## used for the treatment of inflammation, pain, thrombosis and rheumatism.


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Masaaki Matsuo, Daijiro Hagiwara, Hiroshi Miyake: Peptide compounds having substance P antagonism, processes for preparation thereof and pharmaceutical composition comprising the same. Fujisawa Pharmaceutical Company, Oblon Spivak McClelland Maier & Neustadt, November 17, 1992: US05164372 (67 worldwide citation)

Peptide compounds having Substance P antagonism of the formula: ##STR1## wherein R.sup.1 is lower alkyl, aryl, arylamino, pyridyl, pyrrolyl, pyrazolopyridyl, quinolyl, or a group of the formula: ##STR2## wherein the symbol of a line and dotted line is a single bond or a double bond; X is CH or N; Z ...


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Masaaki Matsuo, Daijiro Hagiwara, Hiroshi Miyake: Peptides having tachykinin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same.. Fujisawa Pharmaceutical Co, August 28, 1991: EP0443132-A1 (56 worldwide citation)

A compound of forumula: wherein R is aryl, or a group of the formula : wherein X is CH or N, and Z is O or N-R, in which R is hydrogen or lower alkyl, R is hydroxy or lower alkoxy, R is hydrogen or lower alkyl which may have suitable substituent(s), R is ar(lower)alkyl which may have suitable substi ...


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Hiroshi Wada, Kazuhiro Ishii, Nobuchika Tsumagari, Masaaki Matsuo, Mikio Matsumoto: Naphthalene derivatives and method for preparation thereof. Tanabe Seiyaku, Browdy and Neimark, January 21, 1986: US04565877 (23 worldwide citation)

A naphthalene derivative of the formula: ##STR1## wherein R.sup.1 is hydrogen and R.sup.2 is lower alkyl or phenyl-lower alkyl; or R.sup.1 and R.sup.2 are combined together to form lower alkylene; X is halogen; and the absolute configuration at the asymmetric carbon atom shown by the asterisk is eit ...


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Masaaki Matsuo, Kiyoshi Tsuji, Takashi Ogino, Nobukiyo Konishi: Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same. Fujisawa Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt P C, August 27, 1996: US05550147 (18 worldwide citation)

The present invention relates to new pyrazole derivatives represented by the following general formula (I) ##STR1## wherein R.sup.1 is aryl which is substituted with substituent(s) selected from the group consisting of lower alkylthio, cyclo(lower)alkyl, hydroxy, hydroxy(lower)alkyl, cyano, lower al ...


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Masaaki Matsuo, Kiyoshi Tsuji, Nobukiyo Konishi, Katsuya Nakamura: Thiophene derivatives. Fujisawa Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt P C, November 5, 1996: US05571810 (17 worldwide citation)

This invention relates to new thiophene derivatives having antiinflammatory and analgesic activities and represented by the general formula [I]: ##STR1## wherein R.sup.1 is hydrogen, halogen, cyano, substituted lower alkyl, substituted or unsubstituted lower alkenyl, acyl, nitro, substituted or unsu ...


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Masaaki Matsuo, Tsuyoshi Saitoh, Takekazu Yamashita, Michio Nakajima, Akira Kitaguchi, Hideki Toki: Semiconductor device test board and method for evaluating semiconductor devices. Mitsubishi Electric Systems LSI Design Corporation, Mitsubishi Denki Kabushiki, Leydig Voit & Mayer, September 5, 2000: US06114866 (16 worldwide citation)

A semiconductor device test board solves a problem with conventional test boards in that test results obtained through a burn-in procedure could be identified only before the test board is taken out of a burn-in oven. Hence, conventional test boards required additional steps for checking the test re ...


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Ikuo Ueda, Masaaki Matsuo, Kiyoshi Tsuji, Hiroyuki Okumura, Osamu Nakaguchi: Piperazine compounds and antithrombotic pharmaceutical composition comprising the same. Fujisawa Pharmaceutical, Oblon Fisher Spivak McClelland & Maier, January 10, 1989: US04797399 (15 worldwide citation)

The present invention relates to N-containing fused heterocyclic compounds of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are each hydrogen, halogen, aryl, lower alkyl, halo (lower) alkyl or nitro,


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Masaaki Matsuo, Kazuo Okumura, Shinji Shigenaga, Hiroshi Matsuda: New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same.. Fujisawa Pharmaceutical Co, February 24, 1993: EP0528337-A1 (15 worldwide citation)

A compound of the formula : wherein R is lower alkyl optionally substituted with halogen, lower alkylamino or lower alkyl(acyl)amino; cyclo(lower)alkyl; tricycloalkyl; aryl optionally substituted with lower alkoxy; or a heterocyclic group; R is hydrogen or halogen, or R and R are taken together with ...


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