1
Dunican L K Prof, Mccormback Ashling, Stapelton Cliona, Burke Kevin, O& 039, Donohue Michael, Marx Achim Dr, Moeckel Bettina Dr: (gpi) From bacteria. Degussa, Nat Univ Ireland, March 28, 2001: EP1087015-A2 (9 worldwide citation)

Isolated polynucleotide containing a polynucleotide sequence selected from the group a) polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID no. 2, b) polynucleotide which codes for a polypeptide which contains ...


2
Moeckel Bettina Dr, Pfefferle Walter Dr, Marx Achim Dr: Nucleotide sequences coding for the genes succ and sucd. Degussa, May 30, 2001: EP1103611-A1 (4 worldwide citation)

Isolated polynucleotide (I), encoding corynebacterium succinyl-CoA synthetase, is new. Isolated polynucleotide (I), containing a sequence representing the sucC and/or sucD gene, is at least 70% identical with a sequence that encodes a polypeptide (IIa) containing fully defined sequence of (402 amino ...


3
Marx Achim Dr, Moeckel Bettina Dr, Pfefferle Walter Dr, Sahm Hermann Dr, de Graaf Albert Dr, Eggeling Lothar Dr: Process for the fermentative production of l-amino acids using coryneform bacteria. Degussa, Forschungszentrum Juelich, August 23, 2000: EP1029919-A2 (2 worldwide citation)

Preparation of L-amino acids comprises fermentation of coryneform bacteria in which the nucleotide sequence encoding glutamate dehydrogenase (GDH) is amplified, especially over-expressed.


4
Moeckel Bettina Dr, Pfefferle Walter Dr, Marx Achim Dr: Polynucleotide sequences from corynebacterium glutamicum coding for succinate dehydrogenase subunits (sdha, sdhb, sdhc). Degussa, June 13, 2001: EP1106684-A1 (2 worldwide citation)

Isolated polynucleotide (I) from coryneform bacteria encoding succinate dehydrogenase, is new. Isolated polynucleotide (I) from coryneform bacteria encoding succinate dehydrogenase, is new. (I) is selected from: (a) a polynucleotide which is at least 70% identical with a sequence that encodes a poly ...


5
MARX ACHIM DR, WENDISCH VOLKER F PROF DR, RITTMANN DORIS, BUCHHOLZ STEFAN DR: [fr] Fabrication microbiologique dacides 3-hydroxypropion, [de] Mikrobiologische Herstellung von 3-Hydroxypropionsäure, [en] Microbiological production of 3-hydroxypropionic acid. EVONIK DEGUSSA, FORSCHUNGSZENTRUM JUELICH, April 14, 2010: EP2175024-A2

[en] Genetically modified cells, exhibiting an increased activity of an enzyme E 1a that catalyzes the conversion of pyruvate to oxaloacetate, or of an enzyme E 1b that catalyzes the conversion of phosphoenol pyruvate to oxaloacetate an increased activity of an enzyme E 2 that catalyzes the conversi ...


6
Farwick Mike Dr, Brehme Jennifer, Hermann Thomas Dr, Bathe Brigitte, Marx Achim Dr, Moeckel Bettina, Rieping Mechthild, Ermantraut Eugen, Ellinger Thomas, Huthmacher Klaus Dr, Pfefferle Walter Dr: Method for monitoring a fermentation process using an expression array. Degussa, January 23, 2002: EP1174520-A2

The present invention provides arrays of single- or doublestranded desoxyribonucleic acid (DNA) probes immobilized on solid supports and methods for using these probe arrays to monitor specific nucleic acid sequences contained in a biological sample especially to monitor the nucleic acid sequences i ...


7
Dusch Nicole Dr, Marx Achim Dr, Pfefferle Walter Dr, Thierbach Georg Dr: Process for the production by fermentation of d-pantothenic acid and/or its salts. Degussa, October 9, 2002: EP1247868-A2

Preparation of D-pantothenic acid (I) and/or its salts, or fodder additives containing them, comprises fermenting a coryneform bacterium (CB), especially one that already produces (I), in which activity of the endogenous glyA gene (serine hydroxymethyl transferase) is increased, particularly by over ...


8
Bathe Brigitte Dr, Marx Achim Dr, Pfefferle Walter Dr, Thierbach Georg Dr: Process for the production of amino acids using phosphoglucose isomerases from coryneform bacteria. Degussa, November 12, 2003: EP1361278-A2

The invention relates to proteins having phosphoglucose isomerase activity from coryneform bacteria, to coryneform bacteria containing such proteins, and to processes for the production of L-amino acids, especially L-lysine, using such proteins.


9
Bathe Brigitte Dr, Farwick Mike Dr, Pfefferle Walter Dr, Marx Achim Dr: Process for the preparation of l-lysine using coryneform bacteria which contain an attenuated malate enzyme gene. Degussa, December 3, 2003: EP1367130-A1

The invention relates to a process for the preparation of L-amino acids, in which the following steps are carried out: a) fermentation of the coryneform bacteria which produce the desired L-amino acid and in which at least the gene which codes for the malate enzyme is attenuated, b) concentration of ...


10
Merkamm Muriel, Guyonvarch Armel Prof, Marx Achim Dr: A process for the fermentative preparation of metabolic products and for the nucleotide sequences encoding sod. Degussa, Ct Nat de, February 21, 2001: EP1077261-A2

The invention provides nucleotide sequences encoding for the sod gene and a process for the fermentative preparation of nucleotides, vitamins and L-amino acids, in particular L-lysine, using coryneform bacteria in which the sod gene is amplified.



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