1
Effland Richard Charles, Klein Joseph Thomas, Martin Lawrence Leo: Substituted 3-(pyridinylamino)-indoles and benzo[b]thiophenes, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, October 21, 1992: EP0509402-A1 (11 worldwide citation)

The present invention relates to compounds of the formula I where R1 is hydrogen, loweralkyl, loweralkenyl, loweralkynyl, arylloweralkyl, aminoloweralkyl, loweralkylaminoloweralkyl, formyl, loweralkylcarbonyl, aminoloweralkylcarbonyl or loweralkoxycarbonyl; the group -X-Y= is R2 and R3 being indepen ...


2
Martin Lawrence Leo, Worm Manfred Dr: (Arylmethyl)Aryl-amino-cyclohexanols, -cyclohexanes, -cyclohexenes and intermediates thereof, a process for preparing the same and their use as medicaments.. Hoechst Roussel Pharma, November 3, 1982: EP0063793-A2 (11 worldwide citation)

Compounds of the formula wnerein R and R are each independently hydrogen and lower alkyl R is hydrogen or hydroxyl, m is an integer of 0 or 1, n is an integer of 0 or 1, and when m is 1, n is 0; when m is 0, n is 1, and X and Y are each independently hydrogen, halogen, alkoxy of 1 or 2 carbon atoms, ...


3
Flanagan Denise Mary, Martin Lawrence Leo: Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, April 7, 1993: EP0535645-A2 (11 worldwide citation)

Carbamate Derivatives of 4-Amino-3-isoxazolidinones, 3-Amino-1-hydroxypyrrolidin-2-ones and 1-Amino-1-cyclopropanecarboxylic acid analogs, a process for their preparation and their use as medicaments where R is and R is and to a process for their preparation. The compounds are useful for alleviating ...


4
Martin Lawrence Leo, Davis Larry: Tetrahydrocyclopent[b]indole methanamines and related compounds, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, September 14, 1994: EP0614888-A1 (8 worldwide citation)

There are disclosed various compounds of the formula below, where the various parameters R1, R2, R3, R4, X, m and n are as defined in the specification, which show activities as a monoamine oxidase inhibitor demonstrating a utility for the treatment of depression, and activities as a cholinesterase ...


5
Effland Richard Charles, Klein Joseph Thomas, Martin Lawrence Leo: (b) Thiophenes and 1,2-benzisothiazoles, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, March 31, 1993: EP0534343-A1 (6 worldwide citation)

This invention relates to substituted pyridinylamino-1H-indoles, 1H-indazoles, 2H-indazoles, benzoÄbÜthiophenes and 1,2-benzisothiazoles of the formula wherein Q is S, N or NR; Y is CH, N or NR; R is hydrogen, loweralkyl, loweralkynyl, loweralkenyl, arylloweralkyl, loweralkoxycarbonylaminoloweralkyl ...


6
Kosley Raymond W Jr, Flanagan Denise M, Martin Lawrence Leo, Nemoto Peter Allen: (amino)Acetamides and related (1h-indol-1-yl)-(aminoalkyl)amides, intermediates and a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, October 6, 1993: EP0563916-A1 (4 worldwide citation)

There are disclosed compounds having the formula wherein X is hydrogen, chloro, bromo, fluoro, hydroxy, loweralkoxy, arylloweralkoxy, acyloxy, loweralkylaminocarbonyloxy, diloweralkylaminocarbonyloxy, amino, loweralkylamino, diloweralkylamino, acylamino, loweralkyl or trifluoromethyl; Y is hydrogen, ...


7
Martin Lawrence Leo, Setescak Linda Louise: Substituted 4,10-dihydro-10-oxothieno benzoxepins and intermediates thereof, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, October 3, 1984: EP0120304-A2 (4 worldwide citation)

The present invention relates to substitued 4,10-dihydro-10-oxothieno-benzoxepins of the formula where R is hydrogen or loweralkylcarbonyl; and R and R are each independently hydrogen or loweralkyl, which are useful as anti-inflammatory and analgetic agents, a process for their preparation and inter ...


8
Martin Lawrence Leo, Worm Manfred Dr, Crichlow Charles Anthony: 4-phenyl-1,3-benzodiazepines, method for their preparation, pharmaceutical compositions containing them, and the compounds for use as medicaments.. Hoechst, April 16, 1980: EP0009800-A2 (4 worldwide citation)

Compounds of the formula in which R and R1 are the same or different and each can be hydrogen, alkyl of from 1 to 3 carbon atoms, cycloalkyl- C-C3-alkyl, wherein the cycloalkyl radical has 3 - 6 carbon atoms, or aralkyl having up to 8 carbon atoms, X and Y are the same or different and each can be c ...


9
Martin Lawrence Leo: 5-substituted 1-/4-(1-pyrrolidinyl)-2-butynyl/-2-pyrrolidones and related compounds, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, August 2, 1989: EP0325984-A2 (3 worldwide citation)

There are disclosed compounds of the formula where R1 is loweralkoxycarbonyl, -CH2OH or -CONR3R4, R3 and R4 being independently hydrogen, loweralkyl or arylloweralkyl; and R2 is -CH2CH=CH2, R5 and R6 being independently loweralkyl or alternatively the group -NR5R6 as a whole being R7 being hydrogen, ...


10
Martin Lawrence Leo, Worm Manfred Dr: Spiro(cyclohexane-1,1(3h)-isobenzofuran)s, processes and intermediates for their preparation and pharmaceutical compositions containing them.. Hoechst Roussel Pharma, April 29, 1981: EP0027522-A1 (3 worldwide citation)

The present invention relates to novel spiro [cyclohexane-1,1 min (3 min H)- isobenzofuran]s of the formula wherein R1 is hydrogen; R2 is NR5R6 wherein R5 is hydrogen, loweralkyl; R6 is hydrogen or loweralkyl; R3 is hydrogen, loweralkyl or cycloalkyl having 3 to 7 carbon atoms, inclusive wherein X i ...