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Mark G Allen, Mark R Prausnitz, Devin V McAllister, Florent Paul Marcel Cros: Microneedle devices and methods of manufacture and use thereof. Georgia Tech Research Corporation, Sutherland Asbill & Brennan, January 1, 2002: US06334856 (597 worldwide citation)

Microneedle devices are provided for transport of therapeutic and biological molecules across tissue barriers and for use as microflameholders. In a preferred embodiment for transport across tissue, the microneedles are formed of a biodegradable polymer. Methods of making these devices, which can in ...


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Mark R Prausnitz, Mark G Allen, Sebastien Henry, Devin V McAllister, Donald E Ackley, Thomas Jackson: Devices and methods for enhanced microneedle penetration of biological barriers. Georgia Tech Research Corporation, Ropes & Gray, June 1, 2004: US06743211 (566 worldwide citation)

Microneedle devices and methods of use thereof are provided for the enhanced transport of molecules, including drugs and biological molecules, across tissue by improving the interaction of microneedles and a deformable, elastic biological barrier, such as human skin. The devices and methods act to ( ...


3
Mark R Prausnitz, Mark G Allen, Devin V McAllister, Sebastien Henry: Microneedle device for transport of molecules across tissue. Georgia Tech Research Corporation, Ropes & Gray, January 7, 2003: US06503231 (360 worldwide citation)

Microneedle devices for transport of therapeutic and diagnostic materials and/or energy across tissue barriers, and methods for manufacturing the devices, are provided. The microneedles are hollow and/or porous and have diameters between about 10 nm and 1 mm. The microneedle devices permit drug deli ...


4
Mark R Prausnitz, Mark G Allen, Inder Jeet Gujral: Microneedle device for extraction and sensing of bodily fluids. Georgia Tech Research Corporation, Ropes and Gray, March 18, 2008: US07344499 (301 worldwide citation)

Microneedle devices are provided for controlled sampling of biological fluids in a minimally-invasive, painless, and convenient manner. The microneedle devices permit in vivo sensing or withdrawal of biological fluids from the body, particularly from or through the skin or other tissue barriers, wit ...


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Mark R Prausnitz, Mark G Allen, Inder Jeet Gujral: Microneedle drug delivery device. Georgia Tech Research Corporation, Ropes & Gray, August 26, 2003: US06611707 (192 worldwide citation)

Simple microneedle devices for delivery of drugs across or into biological tissue are provided, which permit drug delivery at clinically relevant rates across or into skin or other tissue barriers, with minimal or no damage, pain, or irritation to the tissue. The devices include a substrate to which ...


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Mark G Allen, Jennifer M English: System, method, and sensors for sensing physical properties. Georgia Tech Research Corporation, Thomas Kayden Horstemeyer & Risley L, August 21, 2001: US06278379 (190 worldwide citation)

Several sensors are provided for determining one of a number of physical roperties including pressure, temperature, chemical species, and other physical conditions. In general, the sensors feature a resonant circuit with an inductor coil which is electromagnetically coupled to a transmitting antenna ...


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Mark G Allen, Jennifer M English: System and method for the wireless sensing of physical properties. Georgia Tech Research, Thomas Kayden Horstemeyer & Risley L, August 29, 2000: US06111520 (183 worldwide citation)

Several sensors are provided for determining one of a number of physical properties including pressure, temperature, and other physical conditions. In general, the sensors feature a resonant circuit with an inductor coil which is electromagnetically coupled to a transmitting antenna. When an excitat ...


9
Mark R Prausnitz, Mark G Allen, Inder Jeet Gujral: Microneedle drug delivery device. Georgia Tech Research Corporation, Fish & Neave IP Group Ropes & Gray, June 5, 2007: US07226439 (116 worldwide citation)

Simple microneedle devices for delivery of drugs across or into biological tissue are provided, which permit drug delivery at clinically relevant rates across or into skin or other tissue barriers, with minimal or no damage, pain, or irritation to the tissue. The devices include a substrate to which ...


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Ari Glezer, Mark G Allen, David J Coe, Barton L Smith, Mark A Trautman, John W Wiltse: Synthetic jet actuator and applications thereof. Georgia Tech Research Corporation, Thomas Kayden Horstemeyer & Risley, June 2, 1998: US05758823 (110 worldwide citation)

Synthetic jet actuator, which can be micromachined if desired, generates a synthetic jet stream characterized by a series of successive vortices that can be used for effectively entraining adjacent fluid. The synthetic jet actuator can be used to bend, or vector, a jet stream from another jet actuat ...