1
Mark Deem, Hanson Gifford III, Denise Demarais, Douglas Sutton, Erik Thai, Mark Gelfand, Howard R Levin: Methods and apparatus for renal neuromodulation. Ardian, Perkins Coie, January 26, 2010: US07653438 (380 worldwide citation)

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the ...


2
Denise Demarals, Hanson Gifford III, Mark Deem, Howard R Levin, Mark Gelfand, Nicolas Zadno: Methods and apparatus for monopolar renal neuromodulation. Ardian, Perkins Coie, March 6, 2012: US08131371 (278 worldwide citation)

Methods and apparatus are provided for monopolar neuromodulation, e.g., via a pulsed electric field. Such monopolar neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or bl ...


3
Denise Demarais, Hanson Gifford III, Mark Deem, Douglas Sutton, Howard R Levin, Mark Gelfand: Methods for catheter-based renal denervation. Ardian, Perkins Coie, April 3, 2012: US08150520 (254 worldwide citation)

Methods and apparatus are provided for treating end-stage renal disease, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or e ...


4
Denise Demarais, Hanson Gifford III, Mark Deem, Douglas Sutton, Howard R Levin, Mark Gelfand: Methods for renal neuromodulation. Ardian, Perkins Coie, March 27, 2012: US08145317 (247 worldwide citation)

Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusio ...


5
Denise Demarais, Hanson Gifford III, Mark Deem, Douglas Sutton, Howard R Levin, Mark Gelfand: Methods and apparatus for bilateral renal neuromodulation. Ardian, Perkins Coie, April 3, 2012: US08150519 (247 worldwide citation)

Methods and apparatus are provided for bilateral renal neuromodulation, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or el ...


6
Denise Demarais, Hanson Gifford III, Mark Deem, Douglas Sutton, Howard R Levin, Mark Gelfand: Methods for treating a condition or disease associated with cardio-renal function. Ardian, Perkins Coie, May 8, 2012: US08175711 (243 worldwide citation)

Methods and apparatus are provided for treating congestive heart failure, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or ...


7
Mark Deem, Denise Demarais, Douglas Sutton, Hanson Gifford III, Howard R Levin, Mark Gelfand, Benjamin J Clark: Methods and apparatus for renal neuromodulation. Ardian, Perkins Coie, March 27, 2012: US08145316 (156 worldwide citation)

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the ...


8
Denise Demarais, Hanson Gifford III, Mark Deem, Nicolas Zadno, Benjamin J Clark, Andrew Wu, Kenneth J Michlitsch: Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen. Medtronic Ardian Luxembourg r l, January 8, 2013: US08347891 (141 worldwide citation)

Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first posit ...


9
Denise Demarais, Hanson Gifford III, Mark Deem, Nicolas Zadno, Benjamin J Clark, Andrew Wu, Kenneth J Michlitsch: Apparatus for performing a non-continuous circumferential treatment of a body lumen. Medtronic Ardian Luxembourg r l, June 4, 2013: US08454594 (115 worldwide citation)

Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first posit ...


10
Hanson S Gifford, Mark Deem: Methods and apparatus for non-invasively treating atrial fibrillation using high intensity focused ultrasound. Cierra, Townsend and Townsend and Crew, J Feuchtwang Esq, December 25, 2007: US07311701 (31 worldwide citation)

Methods and apparatus are provided for non-invasively treating patent foramen ovale using an ultrasound imaging system and a high intensity focused ultrasound system to selectively target high intensity ultrasound energy on either or both of a patient's septum primum or septum secundum.