1
Mark C Shults, Christopher C Capelli, Stuart J Updike: Biological fluid measuring device. Markwell Medical Institute, Olson & Hierl, July 12, 1988: US04757022 (911 worldwide citation)

A biological fluid measuring device for determining the presence and the amounts of substances in a biological fluid without the need for dilution of the fluid comprises a main housing including electronic circuit means and at least one elecrode, and a cartridge having a membrane. The cartridge is r ...


2
Mark C Shults, Stuart J Updike, Rathbun K Rhodes: Device and method for determining analyte levels. Medlen and Carroll, December 14, 1999: US06001067 (840 worldwide citation)

Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices com ...


3
John F Burd, Peter G Jacobs, William J Sell, Mark C Shults: Systems and methods for remote monitoring and modulation of medical devices. DexCom, Knobbe Martens Olson & Bear, May 6, 2003: US06558321 (753 worldwide citation)

The present invention relates generally to the field of healthcare. Particularly, in the remote monitoring and modulation of a medical device on or in a subject. The present invention provides both systems and methods for remote monitoring of a subject, as well remote treatment of a subject (e.g. mo ...


4
Mark C Shults, Stuart J Updike, Rathbun K Rhodes: Device and method for determining analyte levels. DexCom, Knobbe Martens Olson & Bear, May 25, 2004: US06741877 (700 worldwide citation)

Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices com ...


5
James H Brauker, Mark C Shults, Mark A Tapsak: Membrane for use with implantable devices. Dexcom, Knobbe Martens Olson & Bear, March 9, 2004: US06702857 (693 worldwide citation)

The present invention provides a biointerface membrane for use with an implantable device that interferes with the formation of a barrier cell layer including; a first domain distal to the implantable device wherein the first domain supports tissue attachment and interferes with barrier cell layer f ...


6
Mark C Shults, Stuart J Updike, Rathbun K Rhodes, Barbara J Gilligan, Mark A Tapsak: Device and method for determining analyte levels. DexCom, Knobbe Martens Olson & Bear, March 1, 2005: US06862465 (605 worldwide citation)

Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices incl ...


7
Mark C Shults, Stuart J Updike, Rathbun K Rhodes: Device and method for determining analyte levels. DexCom, Knobbe Martens Olson & Bear, September 19, 2006: US07110803 (561 worldwide citation)

Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices com ...


8
Mark A Tapsak, Rathbun K Rhodes, Mark C Shults, Jason D McClure: Techniques to improve polyurethane membranes for implantable glucose sensors. DexCom, Knobbe Martens Olson & Bear, June 5, 2007: US07226978 (535 worldwide citation)

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observab ...


9
Mark C Shults, Stuart J Updike, Rathbun K Rhodes, Barbara J Gilligan, Mark A Tapsak: Device and method for determining analyte levels. DexCom, Knobbe Martens Olson & Bear, November 14, 2006: US07136689 (459 worldwide citation)

Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices incl ...


10
Rathbun Rhodes, Mark A Tapsak, James H Brauker, Mark C Shults: Sensor head for use with implantable devices. DexCom, Knobbe Martens Olson & Bear, December 30, 2008: US07471972 (428 worldwide citation)

The present invention provides a sensor head for use in an implantable device that measures the concentration of an analyte in a biological fluid which includes: a non-conductive body; a working electrode, a reference electrode and a counter electrode, wherein the electrodes pass through the non-con ...