1
Brian J Erickson, Michael E Hilgers, Tracy A Hendrickson, J Edward Shapland, Frank A Solomon, Mark B Knudson: Interstitial fluid collection and constituent measurement. Integ Incorporated, Merchant Gould Smith Edill Welter & Schmidt, December 10, 1996: US05582184 (868 worldwide citation)

An apparatus and method is disclosed for obtaining and measuring constituents in a sample of body fluid. The apparatus includes a member which is sized to penetrate into at least the dermal layer of skin to collect a sample of body fluid located within the dermal layer.


2
James E Shapland, Mark B Knudson, Jin Shimada: Drug delivery apparatus and method. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, February 15, 1994: US05286254 (568 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall ...


3
J Edward Shapland, Keith R Hildelbrand, Joel R Racchini, Jin Shimada, Mark B Knudson: Polymer matrix drug delivery apparatus. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt P A, September 15, 1998: US05807306 (452 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue using a catheter device including a polymer matrix containing a drug. The drug is actively transported from the polymer matrix to the internal body tissue using iontophoresis or phonophoresis. In addition, the ...


4
Brian J Erickson, Michael E Hilgers, Tracy A Hendrickson, J Edward Shapland, Frank A Solomon, Mark B Knudson: Interstitial fluid collection and constituent measurement. Integ Incorporated, Merchant Gould Smith Edell Welter & Schmidt P A, May 5, 1998: US05746217 (446 worldwide citation)

An apparatus and method is disclosed for obtaining and measuring constituents in a sample of body fluid. The apparatus includes a member which is sized to penetrate into at least the dermal layer of skin to collect a sample of body fluid located within the dermal layer.


5
James E Shapland, Mark B Knudson, Jin Shimada: Phoretic balloon catheter with hydrogel coating. Cortrak Medical, Moore & Hansen, May 13, 1997: US05628730 (401 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall ...


6
Brian J Erickson, Michael E Hilgers, Tracy A Hendrickson, J Edward Shapland, Frank A Solomon, Mark B Knudson: Interstitial fluid collection and constituent measurement. Integ Incorporated, Merchant Gould Smith Edell Welter & Schmidt P A, October 13, 1998: US05820570 (332 worldwide citation)

An apparatus and method is disclosed for obtaining and measuring constituents in a sample of body fluid. The apparatus includes a member which is sized to penetrate into at least the dermal layer of skin to collect a sample of body fluid located within the dermal layer.


7
James E Shapland, Mark B Knudson, Jin Shimada, Keith R Hildebrand: Drug delivery apparatus and method. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, February 1, 1994: US05282785 (294 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall ...


8
Joel R Racchini, James E Shapland, Mark B Knudson, Jin Shimada, Keith R Hildebrand: Porous balloon for selective dilatation and drug delivery. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, October 17, 1995: US05458568 (288 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively wetting a membrane within the device, making the membrane permeable and allowing t ...


9
Mark B Knudson, Richard R Wilson, Katherine S Tweden, Timothy R Conrad: Obesity treatment with electrically induced vagal down regulation. EnteroMedics, Merchant & Gould P C, January 23, 2007: US07167750 (257 worldwide citation)

At least one of a plurality of disorders of a patient characterized at least in part by vagal activity innervating at least one of a plurality of organs of the patient is treated by a method that includes positioning a neurostimulator carrier around a body organ of the patient where the organ is inn ...


10
James E Shapland, Keith R Hildebrandt, Mark B Knudson: Method for iontophoretically delivering drug adjacent to a heart. Cortrak Medical, Merchant Gould Smith Edell Welter & Schmidt, March 19, 1996: US05499971 (206 worldwide citation)

A drug delivery apparatus and method for iontophoretically delivering a drug locally to internal body tissue. The iontophoretic delivery apparatus and method include a current source producing a net flow of current in a desired direction with high frequency waveforms which enhance delivery and minim ...