21
James H Brauker, Mark Shults, Mark A Tapsak: Membrane for use with implantable devices. DexCom, Knobbe Martens Olson & Bear, September 23, 2014: US08840552 (11 worldwide citation)

The present invention provides a biointerface membrane for use with an implantable device that interferes with the formation of a barrier cell layer including; a first domain distal to the implantable device wherein the first domain supports tissue attachment and interferes with barrier cell layer f ...


22
Mark A Tapsak, Edward Di Domenico: Silalkylenesiloxane copolymer materials and methods for their preparation. Medtronic, Thomas Berry, Kenneth Collier, Girma Wolde Michael, March 18, 2003: US06534587 (10 worldwide citation)

Symmetric and asymmetric cyclic silalkylenesiloxane monomers and copolymers thereof, as well as crosslinked and/or reinforced silalkylenesiloxane copolymers, medical devices containing such materials, and methods of preparation.


23
Mark A Tapsak, Rathbun K Rhodes, Mark C Shults, Jason D McClure: Techniques to improve polyurethane membranes for implantable glucose sensors. DexCom, Knobbe Martens Olson & Bear, November 1, 2011: US08050731 (8 worldwide citation)

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observab ...


24
Mark A Tapsak, Rathbun K Rhodes, Mark C Shults, Jason D McClure: Techniques to improve polyurethane membranes for implantable glucose sensors. DexCom, Knobbe Martens Olson & Bear, November 8, 2011: US08053018 (8 worldwide citation)

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observab ...


25
Peter C Simpson, James H Brauker, Paul V Goode, Apurv U Kamath, James R Petisce, Kum Ming Woo, Melissa A Nicholas, Robert J Boock, Monica A Rixman, John Burd, Rathburn K Rhodes, Mark A Tapsak: Dual electrode system for a continuous analyte sensor. DexCom, Knobbe Martens Olson & Bear, July 9, 2013: US08483793 (7 worldwide citation)

Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.


26
James H Brauker, Mark A Tapsak, Sean T Saint, Apurv U Kamath, Paul V Neale, Peter C Simpson, Michael Robert Mensinger, Dubravka Markovic: Integrated delivery device for continuous glucose sensor. DexCom, Knobbe Martens Olson & Bear, June 11, 2013: US08460231 (7 worldwide citation)

Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) ...


27
Mark C Shults, Stuart J Updike, Rathbun K Rhodes, Barbara J Gilligan, Mark A Tapsak: Device and method for determining analyte levels. DexCom, Knobbe Martens Olson & Bear, April 10, 2012: US08155723 (6 worldwide citation)

Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices incl ...


28
Michael Eric Benz, Christopher M Hobot, David L Miller, David A Pearson, Mark A Tapsak, Edward DiDomenico, Randall V Sparer: Compounds containing silicon-containing groups, medical devices, and methods. Medtronic, Mueting Raasch & Gebhardt P A, January 10, 2006: US06984700 (6 worldwide citation)

Compounds that include silicon-containing groups, and optionally urethane groups, urea groups, or combinations thereof (i.e., polyurethanes, polyureas, or polyurethane-ureas), as well as materials and methods for making such compounds.


29
James Petisce, Mark A Tapsak, Peter C Simpson, Victoria Carr Brendel, James H Brauker: Oxygen enhancing membrane systems for implantable devices. DexCom, Knobbe Martens Olson & Bear, August 28, 2012: US08255030 (5 worldwide citation)

The present invention relates generally to systems and methods for increasing oxygen availability to implantable devices. The preferred embodiments provide a membrane system configured to provide protection of the device from the biological environment and/or a catalyst for enabling an enzymatic rea ...


30
Michael Eric Benz, Christopher M Hobot, David L Miller, David A Pearson, Mark A Tapsak, Edward DiDomenico, Randall V Sparer: Compounds containing silicon-containing groups, medical devices, and methods. Medtronic, James H Ackley, April 29, 2008: US07365134 (5 worldwide citation)

Compounds that include silicon-containing groups, and optionally urethane groups, urea groups, or combinations thereof (i.e., polyurethanes, polyureas, or polyurethane-ureas), as well as materials and methods for making such compounds.