1
Manuel T Alonso: Heart valve prosthesis. Medtronic, Robert J Klepinski, July 16, 1991: US05032128 (471 worldwide citation)

A heart valve prosthesis and method for replacement of the same are disclosed. The prosthesis includes a sewing ring for permanent attachment to heart tissue, and a valve assembly which is replaceably mounted within the sewing ring in a spaced-apart relationship to define a cylindrical cutting path ...


2
Manuel T Alonso: Heart valve prosthesis. Tascon Medical Technology Corporation, Reed A Duthler, Joseph F Breimayer, John L Rooney, July 14, 1987: US04680031 (218 worldwide citation)

A "tissue valve type" heart valve prosthesis is disclosed which has a biocompatible plastic sewing ring adapted to be surgically implanted into the mitral, aortic or tricuspid annulus of the human heart. The sewing ring has internal square threads and a biocompatible fabric mesh or cloth is embedded ...


3
Manuel T Alonso: Means for improving biocompatibility of implants, particularly of vascular grafts. Medtronic, Reed A Duthler, August 6, 1991: US05037377 (165 worldwide citation)

Implants containing a reasonably biocompatible fabric, which is to be exposed to blood flow after implantation, are rendered biocompatible and substantially impervious to blood, by applying a collagen composition containing soluble collagen, and preferably also collagen fibers, to the fabric in such ...


4
Manuel T Alonso: Heart valve prosthesis. Tascon Medical Technology Corporation, Reed A Duthler, Joseph F Breimayer, January 9, 1990: US04892541 (91 worldwide citation)

A "tissue valve type" heart valve prosthesis is disclosed which has a biocompatible plastic sewing ring adapted to be surgically implanted into the mitral, aortic or tricuspid annulus of the human heart. The sewing ring has internal square threads and a biocompatible fabric mesh or cloth is embedded ...


5
Manuel T Alonso: Mechanical heart valve prosthesis. Medtronic, Reed A Duthler, Joseph F Breimayer, June 19, 1990: US04935030 (83 worldwide citation)

A mechanical heart valve prosthesis has an annular base which defines a passageway for blood flow, and a pair of valve leaflets hingedly mounted within the annular base for regulating direction of the blood flow. The hinge mechanism includes camming indentations or hinge cavities located substantial ...