1
Robert S Langer, David M Lynn, David Putnam, Mansoor M Amiji, Daniel G Anderson: Biodegradable poly(β-amino esters) and uses thereof. Massachusetts Institute of Technology, Brenda Herschbach Jarrell, C Hunter Baker, Choate Hall & Stewart, February 14, 2006: US06998115 (61 worldwide citation)

Poly(β-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably b ...


2
Mansoor M Amiji: Drug delivery using pH-sensitive semi-interpenetrating network hydrogels. Northeastern University, Weingarten Schurgin Gagnebin & Hayes, May 18, 1999: US05904927 (57 worldwide citation)

Drug-delivery devices and methods of their use are disclosed, which devices consist of at least a semi-interpenetrating network (semi-IPN) hydrogel comprising a first, cationic polymer such as chitosan and a second high molecular weight neutral polymer such as polyethylene oxide, the semi-IPN having ...


3
Robert S Langer, David M Lynn, David Putnam, Mansoor M Amiji, Daniel G Anderson: Biodegradable poly(beta-amino esters) and uses thereof. Massachusetts Institute of Technology, Wolf Greenfield & Sacks P C, C Hunter Baker, October 15, 2013: US08557231 (52 worldwide citation)

Poly(β-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably b ...


4
Mansoor M Amiji: Biocompatible articles and method for making same. Northeastern University, Weingarten Schurgin Gagnebin & Hayes, March 23, 1999: US05885609 (28 worldwide citation)

Articles of manufacture and methods of making the same, comprising a cationic polymer which has been surface-modified by a method comprising the steps of swelling a cationic polymer in a medium having a pH value <7; applying a surface-modifying agent to the cationic polymer to form a mixture; and ad ...


5
Robert S Langer, David M Lynn, David Putnam, Mansoor M Amiji, Daniel G Anderson: Biodegradable poly(beta-amino esters) and uses thereof. Massachusetts Institute of Technology, Wolf Greenfield & Sacks P C, C Hunter Baker, Robin A Weatherhead, October 16, 2012: US08287849 (21 worldwide citation)

Poly(β-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably b ...


6
Robert S Langer, David M Lynn, David A Putnam, Mansoor M Amiji, Daniel Griffith Anderson: Biodegradable poly(beta-amino esters) and uses thereof. Massachusetts Institute of Technology, Wolf Greenfield & Sacks P C, August 11, 2015: US09101666 (2 worldwide citation)

Poly(β-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably b ...


7
Mansoor M Amiji, Arun K Iyer: Multifunctional self-assembling polymeric nanosystems. Northeastern University, Wilmer Cutler Pickering Hale and Dorr, November 3, 2015: US09173840

Libraries of nanoparticles comprising therapeutic agents and/or imaging agents are disclosed, as well as methods of making, customizing, and using such libraries of nanoparticles.


8
Mansoor M Amiji, Srinivas Ganta, Pei Chin Tsai: Multimodal diagnostic technology for early stage cancer lesions. Northeastern University, Posternak Blankstein & Lund, April 18, 2017: US09623124

Disclosed herein are compositions of a multimodal detection agent and methods of fabricating the same. The multimodal detection agent comprises a plurality of metallic nanoparticles attached to a surface of a polymeric carrier. The detection agent further comprising one or more target-specific bindi ...


9
Mansoor M Amiji, Ehab S Taqieddin: Hybrid immobilized catalytic system with controlled permeability. Weingarten Schurgin Gagnebin & Lebovici, December 30, 2004: US20040266026-A1

An immobilized catalytic system comprising a carrier layer containing a catalytic entity and a permeable screening layer for providing controlled access between the immobilizing catalytic entity and the surrounding environment and methods of making such systems are disclosed. The carrier layer inclu ...


10
Mansoor M Amiji, Dinesh B Shenoy, Lilian van Vlerken: Nanoparticulate delivery systems for treating multi-drug resistance. Weingarten Schurgin Gagnebin & Lebovici, November 16, 2006: US20060257493-A1

An encapsulated delivery system, and, in particular, a nanoparticulate delivery system representing a qualitatively different approach to overcoming multi-drug resistance while simultaneously administering the chosen drug treatment to a patient, e.g., in a site-specific manner, is disclosed. A compo ...