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Daneshtalab Mohsen, Nguyen Dai Quoc, Ha Chan Minh, Luu Hiep The, Tempest Laurence Mark, Micetich Ronald G: Antiviral compounds.. Synphar Lab, October 4, 1989: EP0335636-A1 (3 worldwide citation)

A heteroaryloxyalkylheterocycle derivative of the Formula I: R-(CH2)n-O-R I is provided wherein: R is a non-fused azole moiety; n is 3, 4, 5, 6, 7 or 8; and R is a non-fused or fused, optionally substituted azole or furyl group, an optionally substituted amino group, or a phenyl group substituted by ...


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Kania Robert Steven, Bender Steven Lee, Borchardt Allen J, Braganza John F, Cripps Stephan James, Hua Ye, Johnson Michael David, Johnson Theodore Otto Jr, Luu Hiep The, Palmer Cynthia Louise, Reich Siegfried Heinz, Tempczyk Russell Anna Maria, Teng Min, Thomas Christine, Varney Michael David, Wallace Michael Brennan, Collins Michael Raymond: Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use. Agouron Pharmaceuticals, PINO Mark J, January 11, 2001: WO/2001/002369 (3 worldwide citation)

Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The inv ...


3
Daneshtalab Mohsen, Nguyen Dai Quoc, Ha Chan Minh, Luu Hiep The, Micetich Ronald G: Antiviral compounds.. Synphar Lab, October 4, 1989: EP0335646-A1 (2 worldwide citation)

There are provided compounds having the general formulae wherein R is an optionally substituted non-fused azole moiety; n is 5, 6, 7 or 8; and R is an optionally substituted, fused or non-fused azole moiety. These compounds have been demonstrated as having antipicornavirus activity. Also described a ...


4
Collins Michael Raymond, Tempczyk Russell Anna Maria, Hua Ye, Johnson Michael David, Bender Steven Lee, Kania Robert Steven, Borchardt Allen J, Braganza John F, Cripps Stephan James, Johnson Theodore Otto Jr, Luu Hiep The, Palmer Cynthia Louise, Reich Siegfried Heinz, Teng Min, Thomas Christine, Varney Michael David, Wallace Michael Brennan: Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use. Agouron Pharma, January 11, 2006: EP1614683-A1 (1 worldwide citation)

Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The inv ...


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Johnson Theodore O Jr, Chu Shao Song, Hua Ye, Luu Hiep The, Reich Siegfried Heinz, Skalitzky Donald James, Yang Yi, Chan Fora P, Eastman Brian Walter, Hendrickson Thomas F: Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis. Agouron Pharma, October 29, 2003: EP1355878-A2

Compounds of the formula (I), where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or ...


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Johnson Theodore O Jr, Chu Shao Song, Hua Ye, Luu Hiep The, Reich Siegfried Heinz, Skalitzky Donald James, Yang Yi, Chan Fora P, Eastman Brian Walter, Hendrickson Thomas F: Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis. Agouron Pharmaceuticals, SIEBURTH Kathryn L, December 20, 2001: WO/2001/096297

Compounds of the formula (I), where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or ...


9
Kania Robert Steven, Bender Steven Lee, Borchardt Allen J, Braganza John F, Cripps Stephan James, Hua Ye, Johnson Michael David, Johnson Theodore Otto Jr, Luu Hiep The, Palmer Cynthia Louise, Reich Siegfried Heinz, Tempczyk Russell Anna Maria, Teng Min, Thomas Christine, Varney Michael David, Wallace Michael Brennan, Collins Michael Raymond: Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use. Agouron Pharma, July 3, 2002: EP1218348-A2

Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The inv ...


10
Johnson Jr Theodore O, Reich Siegfried Heinz, Chan Fora P, Chu Shao Song, Yang Yi, Hua Ye, Luu Hiep The, Eastman Brian Walter, Hendrickson Thomas F: Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis. Agouron Pharma, li huayang, September 1, 2004: CN01813141

Compounds of the formula (I), where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or ...