Ganguly Ashit K, Girijavallabhan Viyyoor M, Lovey Raymond G, Saksena Anil K: Tri-substituted tetrahydrofuran antifungals.. Schering, May 5, 1993: EP0539938-A1 (15 worldwide citation)

An antifungal compound represented by formula ÄIÜ: wherein X is independently both F or both Cl or one X is F and the other is Cl; Y= R' = (C-C) alkyl; (C-C)alkenyl; (C-C)alkynyl; (C-C3/4 )cycloalky or CHR; R = (C-C)perhaloalkyl; COR *CH(OR4)CHOR4 or CHN(R5) R = lower alkyl or H R4 = R or (CH)OR R5 ...

Saksena Anil K, Girijavallabhan Viyyoor M, Lovey Raymond G, Pike Russell E, Wang Haiyan, Liu Yi Tsung, Ganguly Ashit K, Bennett Frank: Tetrahydrofuran antifungals. Schering, October 9, 1996: EP0736030-A1 (5 worldwide citation)

A compound represented by the formula I F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C3 to C8) alkyl group substituted by one or two hydroxy moieties, an ether or ester thereof (e.g., a polyether ester amino acid ester or phosphate e ...



Zhu Zhaoning, Sun Zhong Yue, Venkatraman Srikanth, Njoroge F George, Arasappan Ashok, Malcolm Bruce A, Girijavallabhan Viyyoor M, Lovey Raymond G, Chen Kevin X: Diaryl peptides as ns3-serine protease inhibitors of hepatits c virus. Schering, September 17, 2003: EP1343807-A2 (2 worldwide citation)

The present invention is directed to certain diaryl amide compounds as NS3-Serine protease inhibitors of hepatitis C virus. A particularly preferred compound is of the formula (I).



Ganguly Ashit K, Mccormick Jinping, Lovey Raymond G, Bennett Frank, Saksena Anil K, Girijavallabhan Viyyoor M: Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rna in patients having chronic hepatitis c infection. Schering, August 8, 2001: EP1121370-A1 (1 worldwide citation)

5'-Amino acid esters of ribavirin represented by formula I:wherein R is CH3CH(NH2)-CO-, CH3CH2(CH3)CHCH(NH2)-CO-orH2N(CH2)4CH(NH2)-CO-; preferably R isor a pharmaceutically acceptable salt thereof, e.g., trifluoroacetate, tosylate, mesylate, and chloride, pharmaceutical compositions containing them ...

Sakesena Anil K, Girijavallabhan Viyyoor Moopil, Bogen Stephane L, Lovey Raymond G, Jao Edwin E, Bennett Frank, Mc Cormick Jinping L, Wang Haiyan, Pike Russell E, Liu Yi Tsung, Chan Tin Yau, Zhu Zhaoning, Arasappan Ashok, Chen Kevin X, Venkatraman Srikanth, Parekh Tejal N, Pinto Patrick A, Santhanam Bama, Njoroge F George, Ganguly Ashit K, Saksena Anil K: Novel peptides as ns3-serine protease inhibitors of hepatitis c virus. Schering, Corvas Int, April 23, 2003: EP1303487-A1

The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorder ...