1
Lokanathan M Iyer, Jeffrey B Yim, Kenneth S Lyon: Fiber-optic physiological probes. Abbott Laboratories, Christensen O Connor Johnson & Kindness, May 15, 1990: US04925268 (396 worldwide citation)

Fiber-optic sensors suitable for monitoring physiological analyte concentration. An analyte-permeable matrix is disposed in the light path defined by the axial core at one end of an optical fiber segment. The matrix contains an indicator molecule covalently linked to a polymer, preferably methyl met ...


2
Lokanathan M Iyer, Yanqun Zhao: Fiber-optic detectors with terpolymeric analyte-permeable matrix coating. Abbott Laboratories, Christensen O Connor Johnson & Kindness PLLC, June 17, 1997: US05640470 (150 worldwide citation)

The invention provides fiber-optic detectors with rapid response times for measuring analytes in aqueous solutions, including blood. The detectors, because of their size, accuracy, and sterilizability may be used in vitro. In a preferred embodiment, pellets comprising a unique, permeable terpolymer ...


3
Lokanathan M Iyer, Jeffrey B Yim, Kenneth S Lyon: Fiber-optic physiological probes. Abbott Laboratories, Christensen O Connor Johnson & Kindness, March 19, 1991: US05000901 (48 worldwide citation)

Methods of monitoring analyte concentration in fluids using fiber optic sensors that include analyte permeable matrices disposed in a light path at one end of an optical fiber waveguide. The analyte permeable matrix includes an indicator molecular capable of responding to the analyte in an optically ...


4
Gerald G Vurek, Lokanathan M Iyer, James R Scott: Compound optical probe employing single optical waveguide. Abbott Laboratories, Christensen O Connor Johnson & Kindness, June 2, 1992: US05119463 (38 worldwide citation)

A O.sub.2 /CO.sub.2 /pH compound gas probe comprising a single optical waveguide and a method for making the same. The optical waveguide carries light signals at different wavelengths for monitoring oxygen concentration, carbon dioxide concentration, and pH levels. The probe is designed so that ligh ...


5
Lokanathan M Iyer, Jeffrey B Yim, Kenneth S Lyon: Fiber-optic physiological probes. Abbott Laboratories, Christensen O Connor Johnson & Kindness, June 30, 1992: US05127077 (35 worldwide citation)

Fiber optic sensors suitable for monitoring physiological analyte concentrations are described. The sensors include analyte permeable matrices disposed in a light path defined by the axial core at one end of an optical fiber segment. The matrix contains an indicator molecule covalently linked to a p ...


6
Lokanathan M Iyer, James R Scott, Douglas F Whitfield: Antimicrobial compositions. Optiva, Christensen O Connor Johnson & Kindness PLLC, August 17, 1999: US05939050 (29 worldwide citation)

Antimicrobial compositions comprising at least two antimicrobial agents exhibit reduced MIC values relative to the MIC for the agents making up the combination when measured alone. The compositions are useful as therapeutic agents such as in oral hygiene products.


7
Lokanathan M Iyer, Dawn E Barkans, Brian D Hench: Gums containing antimicrobial agents. Optiva Corporation, Christensen O&apos Connor Johnson Kindness PLLC, June 19, 2001: US06248309 (14 worldwide citation)

Gum compositions containing effective amounts of antimicrobial agents that are released to the oral cavity during chewing. In specific embodiments, the antimicrobial agents are released from the gum at different rates and times.


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Lokanathan M Iyer: Optical coupling method. Abbott Laboratories, Christensen O Connor Johnson & Kindness, February 13, 1990: US04900125 (10 worldwide citation)

Method of reversibly coupling optical fibers using an elastomeric composition adhered to the end of at least one optical fiber. The elastomeric composition remains stable after multiple connections and disconnections and protects the ends of the optical fibers from damage unlike conventional couplin ...


10
Lokanathan M Iyer, Robert E Akridge, James C McInnes: Methods for quantitating the efficacy of oral care products. Koninkiijke Philips Electronics, October 30, 2001: US06309835 (9 worldwide citation)

Methods are included for quantitating the efficacy of oral care products at dislodging cells from biofilm test surfaces or inhibit or delay the accumulation of cells on a test surface. More specifically, the inventive methods measure the effectiveness of compositions and appliances in a test environ ...