1
Peng Cho Tang, Li Sun, Gerald McMahon: 3-heteroaryl-2-indolinone compounds for the treatment of disease. Sugen, Lyon & Lyon, August 11, 1998: US05792783 (164 worldwide citation)

The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.


2
Peng Cho Tang, Li Sun, Gerald McMahon: 3-(4-dimethylaminobenzylidenyl)-2-indolinone and analogues thereof for the treatment of disease. Sugen, Lyon & Lyon, March 23, 1999: US05886020 (126 worldwide citation)

The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.


3
Peng Cho Tang, Li Sun, Gerald McMahon: 3-(4-Bromobenzylindenyl)-2-indolinone and analogues thereof for the treatment of disease. Sugen, Lyon & Lyon, March 16, 1999: US05883113 (125 worldwide citation)

The present invention relates to organic molecules apable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal ell proliferation.


4
Peng Cho Tang, Li Sun, Gerald McMahon: 3-(2-halobenzylidenyl)-2-indolinone compounds for the treatment of disease. Sugen, Lyon & Lyon, November 10, 1998: US05834504 (122 worldwide citation)

The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.


5
Peng Cho Tang, Li Sun, Gerald McMahon: 3-(2-alkoxybenzylidenyl)-2-indolinone and analogues thereof for the treatment of disease. Sugen, Lyon & Lyon, March 16, 1999: US05883116 (82 worldwide citation)

The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.


6
Peng Cho Tang, Todd A Miller, Xiaoyuan Li, Li Sun, Chung Chen Wei, Shahrzad Shirazian, Congxin Liang, Tomas Vojkovsky, Asaad S Nematalla, Michael Hawley: Pyrrole substituted 2-indolinone protein kinase inhibitors. Sugen, Pharmacia & Upjohn Co, Beth A Burrous, Foley & Lardner, June 3, 2003: US06573293 (53 worldwide citation)

The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.


7
Peng Cho Tang, Li Sun, Gerald McMahon: 3-(substituted)-2-indolinones compounds and use thereof as inhibitors of protein kinase activity. Sugen, Lyon & Lyon, October 17, 2000: US06133305 (51 worldwide citation)

The present invention relates to novel 3-(substituted)-2-indolinones compounds and physiologically acceptable salts and prodrugs thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related disorders such as ...


8
Peng Cho Tang, Gerald McMahon, Li Sun: Quinoline compounds. Sugen, Lyon & Lyon, July 22, 1997: US05650415 (48 worldwide citation)

A method of inhibiting cell proliferation or differentiation by exposing a cell to a compound of the formula ##STR1## or a pharmaceutically acceptable salt thereof. Q is selected from the group consisting of NH and S, n is 0 or 1; and R.sub.1-9 are independently selected from the group consisting of ...


9
Peng Cho Tang, Li Sun, Gerald McMahon, G David Harris: 2-indolinone derivatives as modulators of protein kinase activity. Sugen, Foley & Lardner, November 13, 2001: US06316635 (39 worldwide citation)

The present invention relates to novel imidazoly 2-indolinones and physiologically acceptable salts and prodrugs thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.


10
Roy, Wen Chung Chen, Ping Chen, Irene, Tatsang Mak, Xi Liu, Li Zhang, Li Sun, Chenggang Liu: Method and system for multiple GPU support. Via Technologies, Thomas Kayden Horstemeyer & Risley, January 29, 2008: US07325086 (38 worldwide citation)

Supporting multiple graphics processing units (GPUs) comprises a first path coupled to a north bridge device (or a root complex device) and a first GPU, which may include a portion of the first GPU's total communication lanes. A second communication path may be coupled to the north bridge device and ...