1
Laurence A Roth, Stephen Jack Herman: Targeted delivery via biodegradable polymers. Focal, Arnall Golden & Gregory, March 9, 1999: US05879713 (438 worldwide citation)

Delivery of bioactive molecules such as nucleic acid molecules encoding a protein can be significantly enhanced by immobilization of the bioactive molecule in a polymeric material adjacent to the cells where delivery is desired, where the bioactive molecule is encapsulated in a vehicle such as lipos ...


2
Chandrashekhar P Pathak, Amarpreet S Sawhney, Jeffrey A Hubbell, Stephen J Herman, Laurence A Roth, Patrick K Campbell, Kevin M Berrigan, Peter K Jarrett, Arthur J Coury: Apparatus for intraluminal photothermoforming. Focal, Wolf Greenfield & Sacks P C, September 2, 1997: US05662712 (119 worldwide citation)

A method and apparatus for molding polymeric structures in vivo is disclosed. The structures comprise polymers that may be heated to their molding temperature by absorption of visible or near-visible wavelengths of light. By providing a light source that produces radiation of the wavelength absorbed ...


3
Stephen J Herman, Laurence A Roth, Edward L Sinofsky, Douglas W Dickinson Jr: Wire guided laser catheter. C R Bard, Wolf Greenfield & Sacks, July 25, 1989: US04850351 (116 worldwide citation)

A catheter having optical fibers for delivering laser energy to a blood vessel to remove obstructions in the blood vessel is adapted to be guided controllably and selectively by a guide wire to the site to be treated. The catheter includes a central lumen which is open at the distal end of the cathe ...


4
Laurence A Roth, Stephen J Herman, Farhad Khosravi, David Melanson, Michael Dumont, Patrick K Campbell, John C Spiridigliozzi: Devices and methods for application of intraluminal photopolymerized gels. Focal, Wolf Greenfield & Sacks P C, July 14, 1998: US05779673 (113 worldwide citation)

Devices for providing polymeric layers on the interior surface of body lumens and spaces are disclosed. The devices can include proximal and distal occlusion elements to define the treatment space and an optical emitter to provide light for a photopolymerization procedure. The devices may include a ...


5
Laurence A Roth, Stephen J Herman, Carl R Turnquist, Edward L Sinofsky, Jacob Y Wong: Catheter system for controlled removal by radiant energy of biological obstructions. C R Bard, Wolf Greenfield & Sacks, April 4, 1989: US04817601 (81 worldwide citation)

A catheter for delivering radiant energy, such as a laser beam, is used in a technique to controllably apply the radiant energy in a patient's body, such as in a blood vessel. The radiant energy is applied in a manner which erodes biological material and may be used to drill through vascular obstruc ...


6
Chandrashekhar P Pathak, Amarpreet S Sawhney, Jeffrey A Hubbell, Stephen J Herman, Laurence A Roth, Patrick K Campbell, Kevin M Berrigan, Peter K Jarrett, Arthur J Coury: Polymeric article for intraluminal photothermoforming. Focal, Wolf Greenfield & Sacks P C, April 21, 1998: US05741323 (80 worldwide citation)

A method and apparatus for molding polymeric structures in vivo is disclosed. The structures comprise polymers that may be heated to their molding temperature by absorption of visible or near-visible wavelengths of light. By providing a light source that produces radiation of the wavelength absorbed ...


7
Chandrashekhar P Pathak, Amarpreet S Sawhney, Jeffrey A Hubbell, Stephen J Herman, Laurence A Roth, Patrick K Campbell, Kevin M Berrigan, Peter K Jarrett, Arthur J Coury: Apparatus and methods for intraluminal photothermoforming. Focal, Wolf Greenfield & Sacks P C, January 23, 2001: US06176871 (72 worldwide citation)

A method and apparatus for molding polymeric structures in vivo is disclosed. The structures comprise polymers that may be heated to their molding temperature by absorption of visible or near-visible wavelengths of light. By providing a light source that produces radiation of the wavelength absorbed ...


8
Chandrashekhar P Pathak, Amarpreet S Sawhney, Jeffrey A Hubbell, Stephen J Herman, Laurence A Roth, Patrick K Campbell, Kevin M Berrigan, Peter K Jarrett, Arthur J Coury: Methods for intraluminal photothermoforming. Focal, Wolf Greenfield & Sacks P C, December 15, 1998: US05849035 (51 worldwide citation)

A method and apparatus for molding polymeric structures in vivo is disclosed. The structures comprise polymers that may be heated to their molding temperature by absorption of visible or near-visible wavelengths of light. By providing a light source that produces radiation of the wavelength absorbed ...


9
Laurence A Roth, Stephen J Herman, Farhad Khosravi, David Melanson, Michael Dumont: Methods for application of intraluminal photopolymerized gels. Focal, Wolf Greenfield & Sacks P C, September 9, 1997: US05665063 (41 worldwide citation)

Devices for providing polymeric layers on the interior surface of body lumens and spaces are disclosed. The devices can include proximal and distal occlusion elements to define the treatment space and an optical emitter to provide light for a photopolymerization procedure. The devices may include a ...


10
Laurence A Roth, Zheng Zhang, Chad C Huval, Michael A Bouchard, Christopher R Loose: Articles having non-fouling surfaces and processes for preparing the same including pretreatment of articles. Semprus Biosciences Corporation, Bryan Cave, January 21, 2014: US08632838 (11 worldwide citation)

Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, ...