1
P Douglas Walling, Joseph E Bateson, Lance S Kuhn, M Luann Ochs, Kent M Kost, Martin T Gerber, Klaus H Pollmann, Chi Neng A Han: Assay method with enzyme electrode system. Boehringer Mannheim Corporation, D Michael Young, Max J Kenemore, Marilyn L Amick, April 16, 1996: US05508171 (504 worldwide citation)

A new electrochemical biosensor and method of its use. The electrochemical biosensor has a pair of electrodes consisting of a working electrode and a counter electrode made of the same electrically conducting materials. The counter electrode may be the same size or smaller than the working electrode ...


2
David W Burke, Lance S Kuhn, Terry A Beaty, Vladimir Svetnik: System and method for analyte measurement. Roche Diagnostics Operations, Corange International, Woodward Emhardt Moriarty McNett & Henry, March 4, 2008: US07338639 (189 worldwide citation)

A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the ...


3
Lance S Kuhn, Mary L Ochs, Gilbert C Morris: Biosensor and method for hematocrit determination. Boehringer Mannheim Corporation, D Michael Young, Max J Kenemore, Marilyn L Amick, January 31, 1995: US05385846 (173 worldwide citation)

A biosensor and method for determining the hematocrit level of a whole blood sample using electrochemistry. The biosensor includes working and counter electrodes. A porous membrane is impregnated with an electroactive compound and is spatially displaced from the surface of the electrodes. When a who ...


4
David W Burke, Lance S Kuhn, James Maxwell: System and method for determining an abused sensor during analyte measurement. Roche Diagnostics Operations, Roche Operations, Woodard Emhardt Moriarty McNett & Henry, July 12, 2011: US07977112 (84 worldwide citation)

A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the ...


5
David W Burke, Lance S Kuhn, Terry A Beaty, Vladimir Svetnik: System and method for analyte measurement using AC excitation. Roche Diagnostics Operations, Woodard Emhardt Moriarty McNett & Henry, August 5, 2008: US07407811 (57 worldwide citation)

A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the ...


6
David W Burke, Lance S Kuhn, James Maxwell: System and method for determining an abused sensor during analyte measurement. Roche Diagnostic Operations, Roche Operations, Woodard Emhardt Moriarty McNett & Henry, February 10, 2009: US07488601 (48 worldwide citation)

A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the ...


7
David W Burke, Lance S Kuhn, Terry A Beaty, Vladimir Svetnik: System and method for analyte measurement using AC phase angle measurements. Roche Diagnostics Operations, Woodard Emhardt Moriarty McNett & Henry, June 24, 2008: US07390667 (46 worldwide citation)

A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the ...


8
David W Burke, Lance S Kuhn: System and method for analyte measurement employing maximum dosing time delay. Roche Operations, Roche Diagnostics Operations, Woodard Emhardt Moriarty McNett & Henry, October 6, 2009: US07597793 (32 worldwide citation)

A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the ...


9
David W Burke, Lance S Kuhn, Terry A Beaty, Vladimir Svetnik: System and method for determining a temperature during analyte measurement. Roche Diagnostic Operations, Roche Operations, Woodard Emhardt Moriarty McNett & Henry, February 24, 2009: US07494816 (32 worldwide citation)

A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the ...


10
Mary E Brown, Lance S Kuhn, Robert J McEnroe, Rebecca W Muddiman, Mary L Ochs: Electrochemical enzymatic complementation immunoassay. Boehringer Mannheim Corporation, Boehringer Mannheim, D Michael Young, Max J Kenemore, Marilyn L Amick, June 27, 1995: US05427912 (22 worldwide citation)

An immunoassay diagnostic kit, method, and apparatus for electrochemically determining the concentration of an analyte in a sample. A mixture is formed which includes the sample, an enzyme-acceptor polypeptide, an enzyme-donor polypeptide linked to an analyte analog (enzyme-donor polypeptide conjuga ...