1
Kuwabara Yoko, Kimura Eiichiro, Kawahara Yoshio, Nakamatsu Tsuyoshi: Process for producing target substances by fermentation. Ajinomoto, January 26, 2000: EP0974647-A1 (2 worldwide citation)

An object resides in controlling the retaining and dissociation of a gene extrachromosomally for efficient production of an objective substance in a fermentative manner. By culturing and growing a microorganism containing a plasmid carrying a gene disadvantageously functioning for the production of ...


2
Kuwabara Yoko, Kimura Eiichiro, Kawahara Yoshio, Nakamatsu Wataru: Production of objective material by fermentation. Ajinomoto Co, January 6, 1998: JP1998-000087 (2 worldwide citation)

PROBLEM TO BE SOLVED: To obtain new microorganisms capable of controlling retention and deciduation of a gene out of a chromosome and efficiently producing an objective material by having a plasmid containing the gene capable of disadvantageously acting to produce the objective material and a temper ...


3
Kuwabara Yoko, Hashiguchi Kenichi, Nakamatsu Wataru, Kurahashi Osamu, Mori Yukiko, Ito Hisao: Carbamoyl phosphoric acid synthetase gene of coryneform bacterium and method for producing l- arginine. Ajinomoto Co, October 17, 2000: JP2000-287693 (1 worldwide citation)

PROBLEM TO BE SOLVED: To obtain the new subject gene coding for a polypeptide capable of constituting a protein having a specific amino acid sequence and a carbamoyl phosphoric acid synthetase activity, and useful for producing an enzyme of coryneform bacterium and breeding a L-arginine-producing mi ...


4
Kuwabara Yoko: Navigation system, navigation method, and program. Toyota Mapmaster, June 5, 2008: JP2008-128745 (1 worldwide citation)

PROBLEM TO BE SOLVED: To provide a navigation system for performing guidance on an optimum rerouting course also in consideration of turning a vehicle around at an intersection.SOLUTION: This navigation system is equipped with: a map data storage means 42 therein storing map data including data on i ...


5
Kuwabara Yoko, Hashiguchi Kenichi, Nakamatsu Tsuyoshi, Kurahashi Osamu, Mori Yukiko, Ito Hisao: Carbamoyl-phosphate synthetase gene of coryneform bacteria and method for producing l-arginine. Ajinomoto, August 9, 2000: EP1026247-A1

DNA fragments which encodes the large or the small subunit of carbamoyl-phosphate synthetase obtained from the coryneform bacterium, Brevibacterium lactofermentum. A method of producing L-arginine comprising the steps of culturing a coryneform bacterium transformed with said DNA fragments.


6
Toride Yasuhiko, Takahashi Junichi, Isogai Nahoko, Kuwabara Yoko: Methane production inhibitor and feed composition for ruminants. Ajinomoto, March 1, 2006: EP1630226-A2

This invention provides a feed composition for ruminants comprising a microbe having nitrite reductase active, wherein said microbe is selected from the group consisting of intestinal bacteria, coryneform bacteria, Bacillus subtilis, bacteria of the genus Methylophilus, Actinomyces, ruminal bacteria ...


7
Kuwabara Yoko, Kurahashi Osamu, Nakamatsu Tsuyoshi: Method for producing l-arginine. Ajinomoto, December 6, 2000: EP1057893-A1

A gene coding for glutamate dehydrogenase is introduced into a microorganism having L-arginine producing ability to enhance intracellular glutamate dehydrogenase activity and thereby improve the L-arginine producing ability. The present invention provides an improved method for producing L-arginine ...


8
Suga Mikiko, Kuwabara Yoko, Hashiguchi Kenichi, Ito Hisao, Nakamatsu Tsuyoshi, Kurahashi Osamu: Method for producing l-arginine. Ajinomoto, May 10, 2000: EP0999267-A1

Disclosed is a coryneform bacterium having L-arginine-producing ability in which an activity of intracellular arqininosuccinate synthase is enhanced, wherein the activity of intracellular argininosuccinate synthase is enhanced by, for example, increasing copy number of a gene which codes for an argi ...


9
Nonaka Gen, Saitou Takako, Kuwabara Yoko, Matsui Kazuhiko, Sugimoto Shinichi: (Ja) l−グルタミン酸の製造法, (En) Process for producing l-glutamic acid. Ajinomoto, Nonaka Gen, Saitou Takako, Kuwabara Yoko, Matsui Kazuhiko, Sugimoto Shinichi, KAWAGUCHI Yoshiyuki, December 29, 2004: WO/2004/113550

(EN) A process for producing L-glutamic acid, comprising culturing coryneform bacteria capable of L-glutamic acid production in a culture medium so as to attain formation and accumulation of L-glutamic acid in a culturing product and collecting L-glutamic acid from the culturing product, wherein use ...


10
Nonaka Gen, Kuwabara Yoko, Matsui Kazuhiko, Kojima Hiroyuki: (Ja) l−グルタミン酸の製造法, (En) Process for producing l-glutamic acid. Ajinomoto, Nonaka Gen, Kuwabara Yoko, Matsui Kazuhiko, Kojima Hiroyuki, KAWAGUCHI Yoshiyuki, January 27, 2005: WO/2005/007847

(EN) Production of L-glutamic acid is performed by culturing ϝ-proteobacteria capable of producing L-glutamic acid and having been modified so as to realize an increase of quinone oxide reductase activity in a culture medium to thereby attain formation and accumulation of L-glutamic acid in t ...