1
Kunio Doi, Heang Ping Chan, Maryellen L Giger: Method and system for enhancement and detection of abnormal anatomic regions in a digital image. University of Chicago, Oblon Spivak McClelland Maier & Neustadt, March 6, 1990: US04907156 (167 worldwide citation)

A method and system for detecting and displaying abnormal anatomic regions existing in a digital X-ray image, wherein a single projection digital X-ray image is processed to obtain signal-enhanced image data with a maximum signal-to-noise ratio (SNR) and is also processed to obtain signal-suppressed ...


2
Maryellen L Giger, Kunio Doi, Charles E Metz, Fang Fang Yin: Automated method and system for the detection and classification of abnormal lesions and parenchymal distortions in digital medical images. Arch Development Corporation, Oblon Spivak McClelland Maier & Neustadt, July 21, 1992: US05133020 (147 worldwide citation)

A method for automated analysis of abnormalities in the form of lesions and parenchymal distortions using digital images, including generating image data from respective of digital images derived from at least one selected portion of an object, for example, from mammographical digital images of the ...


3
Robert M Nishikawa, Yulei Jiang, Kazuto Ashizawa, Kunio Doi: Methods for improving the accuracy in differential diagnosis on radiologic examinations. Arch Development Corporation, Oblon Spivak McClelland Maier & Neustadt P C, May 2, 2000: US06058322 (144 worldwide citation)

A computer-aided method for detecting, classifying, and displaying candidate abnormalities, such as microcalcifications and interstitial lung disease in digitized medical images, such as mammograms and chest radiographs, a computer programmed to implement the method, and a data structure for storing ...


4
Laura E Fencil, Charles E Metz, Kunio Doi: Method for determination of 3-D structure in biplane angiography. University of Chicago, Oblon Spivak McClelland Maier & Neustadt, October 17, 1989: US04875165 (140 worldwide citation)

A novel method for determination of 3-D structure in biplane angiography, including determining the distance of a perpendicular line from the focal spots of respective x-ray sources to respective image planes and defining the origin of each biplane image as the point of intersection with the perpend ...


5
Roger Engelmann, Kenneth R Hoffmann, Heber MacMahon, Kunio Doi: Method and system for displaying medical images. Arch Development Corporation, Oblon Spivak McClelland Maier & Neustadt P C, November 16, 1999: US05987345 (133 worldwide citation)

A method and system for displaying medical images and computer output from various CAD schemes on the images. Images are loaded into the display system and displayed in a main viewing area. The system can display various CAD schemes, such as the automated detection of lung nodules, interstitial infi ...


6
Kunio Doi, Nobuyuki Nakamori: Method and system for automated computerized analysis of sizes of hearts and lungs in digital chest radiographs. Arch Development, Oblon Spivak McClelland Maier & Neustadt, December 10, 1991: US05072384 (121 worldwide citation)

An automated method and system to determine a number of parameters related to the size and shape of the heart as well as parameters related to the lungs from data derived from digital chest radiographs. A cardiac rectangle enclosing the heart and portions of the surrounding lung tissue is determined ...


7
Kunio Doi, Xuan Chen, Shigehiko Katsuragawa: Method and system for automated selection of regions of interest and detection of septal lines in digital chest radiographs. Arch Development Corporation, Oblon Spivak McClelland Maier & Neustadt, August 30, 1994: US05343390 (118 worldwide citation)

An automated method and system for discriminating between normal lungs and abnormal lungs having interstitial disease and/or septal lines, wherein a large number of adjacent regions of interest (ROIs) are selected, corresponding to an area on a digital image of a patient's lungs. The ROIs each conta ...


8
Akiko Kano, Kunio Doi: Method and system for detection of interval change in temporally sequential chest images. Arch Development Corporation, Oblon Spivak McClelland Maier & Neustadt, October 25, 1994: US05359513 (110 worldwide citation)

A computerized scheme for the analysis of digitized medical images which provides enhancement of interval changes occurring in a pair of temporally sequential images. In the method and apparatus of the invention, a pair of images are digitized and then are subjected to image registration including a ...


9
Naoki Asada, Kunio Doi: Method and system for differential diagnosis based on clinical and radiological information using artificial neural networks. Arch Development Corporation, Oblon Spivak McClelland Maier & Neustadt, October 31, 1995: US05463548 (102 worldwide citation)

A method and system for computer-aided differential diagnosis of diseases, and in particular, computer-aided differential diagnosis using neural networks. A first embodiment of the neural network distinguishes between a plurality of interstitial lung diseases on the basis of inputted clinical parame ...


10
Hiroyuki Yoshida, Shigehiko Katsuragawa, Yali Amit, Kunio Doi: Method, apparatus, and storage medium for detection of nodules in biological tissue using wavelet snakes to characterize features in radiographic images. Arch Development Corporation, Oblon Spivak McClelland Maier & Neustadt P C, June 20, 2000: US06078680 (92 worldwide citation)

A method and apparatus for discrimination of nodules and false positives in digital chest radiographs, using a wavelet snake technique. The wavelet snake is a deformable contour designed to identify the boundary of a relatively round object. The shape of the snake is determined by a set of wavelet c ...