1
John Urquhart, Santosh Kumar Chandrasekaran, Jane Elizabeth Shaw: Bandage for transdermally administering scopolamine to prevent nausea. Alza Corporation, Thomas E Ciotti, Paul L Sabatine, Edward L Mandell, June 28, 1977: US04031894 (204 worldwide citation)

Method and therapeutic system in the form of a bandage that administer scopolamine base transdermally in an initial pulse of 10 to 200 .mu.g/cm.sup.2 of skin that quickly brings the concentration of scopolamine in the plasma to a level at which emesis and nausea are inhibited without intolerable sid ...


2
Santosh Kumar Chandrasekaran, John Urquhart, Jane Elizabeth Shaw: Method and therapeutic system for providing chemotherapy transdermally. Alza Corporation, Thomas E Ciotti, Paul L Sabatine, Edward L Mandell, November 29, 1977: US04060084 (140 worldwide citation)

Method and therapeutic system in the form of a bandage for providing chemotherapy transdermally by administering certain drugs to unbroken skin in an initial priming dose that quickly brings the systemic concentration of drug to a therapeutic level, followed by a substantially constant dosage that h ...


3
Lyle M Bowman, Santosh Kumar Chandrasekaran, Rajesh Patel, Hoa Vinh Vo: Plasticized bioerodible controlled delivery system. Insite Vision Incorporated, Arnold & Porter, April 16, 2002: US06372245 (58 worldwide citation)

A controlled release medicament delivery system comprises a plasticized bioerodible polymer, such as a polyorthoester. Medicament desirably is entrapped in the plasticized polymer. The resulting delivery system is able to release the medicament in a controlled and sustained manner. The formulation i ...


4
John Urquhart, Kumar Chandrasekaran, Jane Shaw: Method and therapeutic system for administering scopolamine transdermally. Alza Corporation, Thomas E Ciotti, Paul L Sabatine, Edward L Mandell, April 14, 1981: US04262003 (52 worldwide citation)

Method and therapeutic system in the form of a bandage that administer scopolamine base transdermally in an initial pulse of 10 to 200 .mu.g/cm.sup.2 of skin that quickly brings the concentration of scopolamine in the plasma to a level at which emesis and nausea are inhibited without intolerable sid ...


5
Robert E Bauman, S Kumar Chandrasekaran, Shaow B Lin, Lyle M Bowman, Thomas B Harvey III: Surface-treated contact lens and method of producing. Sola U, Charles E Cates, David A Lowin, May 19, 1987: US04666249 (41 worldwide citation)

A contact lens for correction of astigmatism is formed from a single polymeric or copolymeric material. The lens has a central optical zone of greater rigidity than a surrounding non-optical zone. The rigidity of the central optical zone is sufficient for it to retain an astigmatism-correcting shape ...


6
Shaow B Lin, Lyle M Bowman, S Kumar Chandrasekaran, Thomas B Harvey III: Surface treatment of soft contact lenses. Sola U, Charles E Cates, David A Lowin, August 18, 1987: US04687816 (14 worldwide citation)

A process for the treatment of a soft contact lens, to increase its resistance to the deposition thereon and diffusion and accumulation therein of substances which will promote its clouding and discoloration in use, and to improve its mechanical strength, includes treating a hydroxyl group-containin ...


7
Samir Roy, Santosh Kumar Chandrasekaran, Katsumi Imamori, Takemitsu Asaoka, Akihiro Shibata, Masami Takahashi, Lyle M Bowman: Quinolone carboxylic acid compositions and related methods of treatment. InSite Vision Incorporated, SSP, Arnold & Porter, February 3, 2004: US06685958 (5 worldwide citation)

The present invention relates to the use of quinolone carboxylic acid formulations in the treatment of ocular and periocular infections. The present invention also relates to sustained release compositions comprising specific quinolone carboxylic acid compounds. The invention also relates to quinolo ...


8
Samir Roy, Santosh Kumar Chandrasekaran, Katsumi Imamori, Takemitsu Asaoka, Akihiro Shibata, Masami Takahashi, Lyle M Bowman: Quinolone carboxylic acid compositions and related methods of treatment. InSite Vision Incorporated, SSP, Arnold & Porter, March 2, 2004: US06699492 (3 worldwide citation)

The present invention relates to the use of quinolone carboxylic acid formulations in the treatment of ocular and periocular infections. The present invention also relates to sustained release compositions comprising specific quinolone carboxylic acid compounds. The invention also relates to quinolo ...


9
Lyle Bowman, S Kumar Chandrasekaran, Roy Duane Archibald, Stephen Pham, David Mufson: Concentrated aqueous azalide formulations. Insite Vision Incorporated, McDermott Will & Emery, September 14, 2010: US07795231 (1 worldwide citation)

The present invention relates to formulations of concentrated azalide antibiotics and methods for making and using them. Specifically, the invention relates to a method of treating an infection comprising administering to a patient in need thereof, an effective amount of a concentrated aqueous azali ...


10
Lyle M Boeman, Santosh Kumar Chandrasekaran, Raiesh Patel: Bioerodible controlled delivery system. Insite Vision Incorporated, ZHANG MINGYU, November 9, 1994: CN93121611

A controlled release medicament delivery system comprises a plasticized or unplasticized bioerodible polymer, such as a polyorthoester, suspended as a discontinuous phase in a hydrophobic liquid such as silicone oil or mineral oil as a continuous phase. Medicament desirably is entrapped at least par ...