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Arnaiz Damian O, Chou You Ling, Kochanny Monica J, Lee Wheeseong, Lu Shou Fu, Mengel Anne, Phillips Gary, Wei Guo Ping, Yu Hongyi: Piperidine derivatives as antagonists of the cc chemokine receptor ccr1 and their use as anti-inflammatory agents. Schering Aktiengesellschaft, Arnaiz Damian O, Chou You Ling, Kochanny Monica J, Lee Wheeseong, Lu Shou Fu, Mengel Anne, Phillips Gary, Wei Guo Ping, Yu Hongyi, June 29, 2006: WO/2006/066948 (32 worldwide citation)

Piperidine derivatives of the following formulae (I) and (II) and their pharmaceutically acceptable salts, which are functional antagonists of the CC chemokine receptor CCR1 and are thus useful as anti inflammatory agents, a pharmaceutical compositions containing said piperidine derivatives or their ...


2
Dunning Laura, Jaroch Stefan, Kochanny Monica J, Lee Wheeseong, Lian Xiongdong, Liang Meina, Lu Shou Fu, Onuffer James, Phillips Gary, Wei Guo Ping, Ye bin: Substituted quinoline ccr5 receptor antagonists. Schering Aktiengesellschaft, Dunning Laura, Jaroch Stefan, Kochanny Monica J, Lee Wheeseong, Lian Xiongdong, Liang Meina, Lu Shou Fu, Onuffer James, Phillips Gary, Wei Guo Ping, Ye bin, HERMENAU Ronald S, January 8, 2004: WO/2004/002960 (18 worldwide citation)

The present invention relates to CCR5 receptor antagonists of formulae (1a) or (1b), enantiomers, diastereomers, salts and solvates thereof wherein R1, R2, R3, R4, R5, and R7 are as defined herein. The invention further includes a method of CCR5-mediated disorders employing such compounds.


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Chou Yuo Ling, Ghannam Ameen, Kochanny Monica J, Lee Wheeseong, Lu Shou Fu, Shaw Kenneth J, Ye bin, Zhao Zuchun: Substituted piperazine antithrombotic pai-1 inhibitors. Schering Aktiengesellschaft, Chou Yuo Ling, Ghannam Ameen, Kochanny Monica J, Lee Wheeseong, Lu Shou Fu, Shaw Kenneth J, Ye bin, Zhao Zuchun, SHAW Melissa A, October 2, 2003: WO/2003/080060 (1 worldwide citation)

This invention is directed to substituted piperazine compounds of formula (I) and their pharmaceutically acceptable salts which are useful as antithrombotic agents by inhibiting plasminogen activator inhibitor-1 (PAI-1). In addition, the present invention relates to pharmaceutical compositions and t ...


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Arnaiz Damian O, Chou You Ling, Kochanny Monica J, Lee Wheeseong, Lu Shou Fu, Mengel Anne, Phillips Gary, Wei Guo Ping, Yu Hongyi: Piperidine derivatives as antagonists of the cc chemokine receptor ccr1 and their use as anti-inflammatory agents. Schering, June 11, 2008: EP1928829-A1

Piperidine derivatives of the following formulae (I) and (II) and their pharmaceutically acceptable salts, which are functional antagonists of the CC chemokine receptor CCR1 and are thus useful as anti inflammatory agents, a pharmaceutical compositions containing said piperidine derivatives or their ...


6
Dunning Laura, Jaroch Stefan, Kochanny Monica J, Lee Wheeseong, Lian Xiongdong, Liang Meina, Lu Shou Fu, Onuffer James, Phillips Gary, Wei Guo Ping, Ye bin: Substituted quinoline ccr5 receptor antagonists. Schering, June 1, 2005: EP1534681-A1

The present invention relates to CCR5 receptor antagonists of formulae (1a) or (1b), enantiomers, diastereomers, salts and solvates thereof wherein R, R, R, R, R, and R are as defined herein. The invention further includes a method of CCR5-mediated disorders employing such compounds.


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Arnaiz Damian O, Chou Yuo Ling, Karanjawala Rushad E, Kochanny Monica J, Lee Wheeseong, Liang Amy Mei, Morrissey Michael M, Phillips Gary B, Sacchi Karna Lyn, Sakata Stephen T, Shaw Kenneth J, Snider R Michael, Wu Shung C, Ye bin, Zhao Zuchun, Griedel Brian D: $I(ortho)-anthranilamide derivatives as anti-coagulants. Schering Aktiengesellschaft, July 1, 1999: WO/1999/032477

This invention is directed to compounds of formula (III) wherein B, C, D, E, R?1¿, R?2¿ and R?3¿ are disclosed herein. These compounds are disclosed as being useful as anti-coagulants.


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Kochanny Monica J, Morrissey Michael M, Ng Howard P: Thio acid derived monocyclic $i(n)-heterocyclics as anticoagulants. Schering Aktiengesellschaft, April 16, 1998: WO/1998/015547

This invention is directed to monocyclic $i(N)-heterocyclics which are substituted by acyclic or cyclic thio derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds t ...


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Kochanny Monica J, Morrissey Michael M, Ng Howard P: Thio acid derived monocyclic -i(n)-heterocyclics as anticoagulants. Schering, August 11, 1999: EP0934310-A1

This invention is directed to monocyclic N-heterocyclics which are substituted by acyclic or cyclic thio derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to tr ...