Kirk Patrick Seward, Isidro M Gandionco, David Gandionco: Dual modulus balloon for interventional procedures. Mercator MedSystems, Townsend And Townsend And Crew, September 18, 2008: US20080228136-A1

A device for interventional surgical or medical procedures is presented. The device is generally in the form of a balloon and is used to position itself or other working elements up against or through lumen walls in the body. The balloon is comprised of at least two materials of different elastic mo ...

Kirk Patrick Seward: Bistable microvalve and microcatheter system. The Regents of the University of California, Eddie E Scott, January 31, 2002: US20020013555-A1

A bistable microvalve of shape memory material is operatively connected to a microcatheter. The bistable microvalve includes a tip that can be closed off until it is in the desired position. Once it is in position it can opened and closed. The system uses heat and pressure to open and close the micr ...

Kirk Patrick Seward: Electroporation microneedle and methods for its use. Endobionics, Townsend And Townsend And Crew, December 26, 2002: US20020198512-A1

Electroporation of cells in target tissues is performed using microneedles having integral electrode structures. In a first embodiment, a pair of electrode structures are disposed on opposite sides of a substance delivery opening on a needle or other tissue-penetrating shaft. In a second embodiment, ...

Kirk Patrick Seward, Lynn Mateel Barr: Methods and systems for inhibiting arrhythmia. EndoBionics, Townsend And Townsend And Crew, August 18, 2005: US20050182071-A1

Methods and systems for treating patients suffering from or at risk of cardiac arrhythmias rely on the injection of amiodarone and other class III anti-arrhythmic drugs into the perivascular space surrounding a cardiac blood vessel. Injection may be achieved using intravascular catheters which advan ...

Anthony Joonkyoo YUN, Kirk Patrick SEWARD: Delivery of agents by microneedle catheter. Palo Alto Institute, Mercator MedSystems, Townsend And Townsend And Crew, January 3, 2008: US20080004596-A1

Luminal diseases are treated by injecting palliative agents into tissue surrounding a target body lumen. A needle catheter may be placed in the target lumen and used to deliver the agent.

Kirk Patrick Seward, Albert P Pisano: Method of interventional surgery. Fish & Richardson PC, March 20, 2003: US20030055400-A1

A method of interventional surgery is described. The method may include inserting an actuator within a body of a vascularized organism and positioning the actuator adjacent a target region within a vessel of the body. The actuator is operated to cause a needle thereof to move in a substantially perp ...

Kirk Patrick Seward, Albert P Pisano: Microfabricated surgical device for interventional procedures. Fish & Richardson PC, March 20, 2003: US20030055446-A1

An actuator for an interventional surgical procedure is described. The actuator may include an actuator body having a distal end and a proximal end. A central expandable section is located between the distal end and the proximal end. The expandable section is operable between an unactuated condition ...

Kirk Patrick Seward, Isidro M Gandionco: Torque mechanism for interventional catheters. EndoBionics, Townsend And Townsend And Crew, November 3, 2005: US20050245862-A1

A torque mechanism for interventional catheters provides direct control over rotary positioning of the distal end of a catheter by rotating a proximal handle of the catheter. The torque mechanism comprises a stiff tube within and running the length of a flexible catheter body tube. The stiff tube is ...

Kirk Patrick Seward: Methods and apparatus for aspiration and priming of inflatable structures in catheters. Mercator Medsystems, Townsend And Townsend And Crew, May 25, 2006: US20060111672-A1

An aspiration baffle comprises an outer tube and an inner core wire. Microholes are provided in the outer tubular member to permit passage of gas but inhibit the passage of liquids. The aspiration baffle is used in a catheter having a balloon or other inflatable structure to assist in priming of the ...

Kirk Patrick Seward, Lynn Mateel Barr, Judith Carol Wilber, Robert Cafferata: Methods and kits for volumetric distribution of pharmaceutical agents via the vascular adventitia and microcirculation. Mercator MedSystems, Townsend And Townsend And Crew, August 24, 2006: US20060189941-A1

Methods and kits for delivering pharmaceutical agents to the adventitia and other regions outside the external elastic lamina (EEL) surrounding a blood vessel utilize a catheter having a needle. The needle is positioned in up to 5 mm beyond the EEL and delivers an amount of pharmaceutical agent suff ...