1
Kimihiro Shimizu, Tsuguji Nakahara, Taketoshi Kinoshita, Jun Takatsuka, Michiko Igarashi: Plasminogen activator derivatives. Nippon Chemiphar Company, Oblon Fisher Spivak McClelland & Maier, February 3, 1987: US04640835 (346 worldwide citation)

Derivatives of a nonimmunogenic plasminogen activator which comprises at least one polyalkylene glycol group chemically bonded with at least one coupling agent to amino acid side chains of said plasminogen activator, wherein said polyalkylene glycol has a molecular weight of about 200-20,000 and is ...


2
Kimihiro Shimizu, Tsuguji Nakahara, Taketoshi Kinoshita: Plasminogen activator derivatives. January 22, 1985: US04495285 (91 worldwide citation)

A derivative of a human-originated non-immunogenic plasminogen activator is disclosed which comprises at least one polyalkylene glycol attached with at least one coupling agent to amino acid side chains of said plasminogen activator, said polyalkylene glycol having a molecular weight of 200-20,000 a ...


3
Kimihiro Shimizu: Thermal change computation apparatus for machine tool and storage medium for executing the computation. Brother Kogyo Kabushiki Kaisha, Oliff & Berridge, December 14, 1999: US06000889 (3 worldwide citation)

In a machine tool having a main shaft, a thermal change amount between two sampling times is computed on the basis of the movement distance of the main shaft during a period from time 0 to time 1a. After thermal change amounts are computed, a total thermal change amount which results from adding the ...


4
Kimihiro Shimizu: Thermal change computation apparatus for machine tool. Brother, Oliff & Berridge, May 22, 2001: US06234730 (2 worldwide citation)

A thermal change computation apparatus is used with a machine tool that includes a machining mechanism for machining a workpiece and a driving mechanism for changing a relative position between the machining mechanism and the workpiece. The apparatus comprises a driving state detecting unit for dete ...


5
Kobayashi Kimihiro Shimizu Con, Hashimoto Yuji Shimizu Constru, Yoshida Takanori Shimizu Const: Apparatus for computing quantities expressed by drawings.. Shimizu Construction, April 1, 1987: EP0215952-A1

A drawing is placed on a panel on an input unit (11), and an operation instruction for calculating the length, area and volume by using a pointing device, such as a stylus pen, and coordinate values on the drawing are input. The input operation instruction and coordinate values are analyzed in an an ...