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Barbosa Antonio Jm Jr, Brunette Steven Richard, Hickey Eugene Richard, Kim Jin Mi, Lawlor Michael David, Lemieux Rene Marc, Mckibben Bryan, Tschantz Matt Aaron, Yu Hui: Pyrimidine derivatives useful as inhibitors of pkc-theta. Boehringer Ingelheim Pharmaceuticals, Barbosa Antonio Jm Jr, Brunette Steven Richard, Hickey Eugene Richard, Kim Jin Mi, Lawlor Michael David, Lemieux Rene Marc, Mckibben Bryan, Tschantz Matt Aaron, Yu Hui, MORRIS Michael P, February 9, 2006: WO/2006/014482 (9 worldwide citation)

Disclosed are novel compounds of formula: (I); wherein X, Y, R1, R2 and R3 are as defined herein, which are useful as inhibitors of PKC-theta and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC-theta, including immunological ...


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Kelly Terence Alfred, Kim Jin Mi, Lemieux Rene Marc, Tschantz Matt Aaron: Derivatives of [6,7-dihydro-5h-imidazo[1,2-&agr;]imidazole-3-sulfonyl]-pyrrolidine-2-carboxylic acid amide as anti-inflammatory agents. Boehringer Ingelheim Pharmaceuticals, RAYMOND Robert P, May 21, 2004: WO/2004/041273 (9 worldwide citation)

Derivatives of 6,7-dihydro-5H-imidazo[1,2-&agr;]imidazole-3-sulfonyl]-pyrrolidine-2-carboxylic acid amide which exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.


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Kim Jin Mi, Lemieux Rene Marc, Mckibben Bryan, Tschantz Matt Aaron, Yu Hui: Substituted benzylimidazoles useful for the treatment of inflammatory diseases. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Kim Jin Mi, Lemieux Rene Marc, Mckibben Bryan, Tschantz Matt Aaron, Yu Hui, MORRIS Michael P, October 12, 2006: WO/2006/107923 (6 worldwide citation)

The invention comprises a class of derivatives of substituted benzylimidazoles of the formula (I) and methods for making the same. These compounds are useful for the treatment of inflammatory conditions.


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Brunette Steven Richard, Kim Jin Mi, Lemieux Rene Marc, Tschantz Matt Aaron: Pyridine derivatives useful as inhibitors of pkc-theta. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Brunette Steven Richard, Kim Jin Mi, Lemieux Rene Marc, Tschantz Matt Aaron, MORRIS Michael P, October 5, 2006: WO/2006/105023 (5 worldwide citation)

Disclosed are novel compounds of formula (I) wherein R1, R2 and R3 are as defined herein, which are useful as inhibitors of PKC-theta and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC-theta, including immunological disorde ...


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Kelly Terence Alfred, Kim Jin Mi, Lemieux Rene Marc: Derivatives of [6,7-dihydro-5h-imidazo[1,2-&agr;] imidazole-3-sulfonylamino]-propionamide and their use as inhibitors upon the interaction of cams and leuko integrins. Boehringer Ingelheim Pharmaceuticals, RAYMOND Robert P, May 21, 2004: WO/2004/041827 (4 worldwide citation)

Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide. A compound of formula (I), which exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.


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Jung Da Woon, Kim Jin Mi, Che Zhong Min, Chang Young Tae, Kim Jin: Screening method for inhibitors of cancer cell invasion and screening system thereof. Industry Academic Cooperation Foundation Yonsei University, Jung Da Woon, Kim Jin Mi, Che Zhong Min, Chang Young Tae, Kim Jin, Yang Boo Hyun Et Al, December 30, 2009: WO/2009/157627 (2 worldwide citation)

This invention relates to a screening method for an inhibitor to cancer cell invasion, comprising the steps of: (a) co-culturing cancer cells and a carcinoma- associated fibroblasts (CAFs) in a multi-chamber containing a upper-chamber, a lower-chamber and a porous filter separating the upper-chamber ...


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Kelly Terence Alfred, Kim Jin Mi, Lemieux Rene M: Derivates of [6, 7-dihydro - 5h - imidazo[1,2- alpha]imidazole-3-sulfonylamino]-propionamide and their use as inhibitors upon the interaction of cams and leukointegrins. Boehringer Ingelheim Pharma, October 18, 2006: EP1712553-A2 (1 worldwide citation)

Derivatives of [6,7-dihydro-5 H -imidazo[1,2 +- ]imidayole-3-sulfonylamino]-propionamide of the formula I which exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.


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Chung Yong Hoon, Han Ji Woong, Lee Hye Ja, Choi Eun Yong, Kim Jin Mi: Concatameric immunoadhesion. Medexgen, November 19, 2003: EP1362062-A1 (1 worldwide citation)

Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discl ...