1
John W Sadler, Andreas N Dorsel, Kenneth L Staton: Apparatus and method for scanning a surface. Agilent Technologies, April 16, 2002: US06371370 (86 worldwide citation)

Apparatus and method for scanning a surface. An optical system generates a light beam to illuminate a surface. A carrier supports the surface for reciprocating motion with respect to the light beam to form one axis of a raster. A propulsion system moves the carrier at a substantially constant speed ...


2
John W Sadler, Andreas N Dorsel, Kenneth L Staton: Apparatus and method for scanning a surface. Agilent Technologies, Gordon M Stewart, July 15, 2003: US06592036 (52 worldwide citation)

Apparatus and method for scanning a surface. An optical system generates a light beam to illuminate a surface. A carrier supports the surface for reciprocating motion with respect to the light beam to form one axis of a raster. A propulsion system moves the carrier at a substantially constant speed ...


3
Kenneth L Staton, Andreas N Dorsel, Arthur Schleifer: Large dynamic range light detection. Agilent Technologies, February 11, 2003: US06518556 (33 worldwide citation)

System for large dynamic range light detection. In one aspect, the system includes a hybrid counting/integrating system for processing a signal from a photomultiplier tube. In another aspect, large dynamic range is achieved in a cascaded detector system utilizing at least one asymmetric beam splitte ...


4
Kenneth L Staton, Andreas N Dorsel, Arthur Schleifer: Large dynamic range light detection. Agilent Technologies, March 12, 2002: US06355921 (27 worldwide citation)

System for large dynamic range light detection. In one aspect, the system includes a hybrid counting/integrating system for processing a signal from a photomultiplier tube. In another aspect, large dynamic range is achieved in a cascaded detector system utilizing at least one asymmetric beam splitte ...


5
John W Sadler, Andreas N Dorsel, Kenneth L Staton: Apparatus and method for scanning a surface. Agilent Technologies, June 7, 2005: US06902112 (19 worldwide citation)

Apparatus and method for scanning a surface. An optical system generates a light beam to illuminate a surface. A carrier supports the surface for reciprocating motion with respect to the light beam to form one axis of a raster. A propulsion system moves the carrier at a substantially constant speed ...


6
Kenneth L Staton, Andreas N Dorsel: Scanning system with calibrated detection and method. Agilent Technologies, June 24, 2003: US06583424 (18 worldwide citation)

A self-calibrating scanning system and method are used in the analysis of biomolecules on a microarray. The self-calibrating scanning system comprises an excitation light source, an optical portion, a detection portion and a calibration portion that includes a calibration apparatus and compensation ...


7
Andreas N Dorsel, Kenneth L Staton, Cassandra Dey, George P Tsai: Apparatus and method for autofocus. Agilent Technologies, November 26, 2002: US06486457 (15 worldwide citation)

A laser generates a collimated laser beam which passes through a lens off-axis. The beam is focused at a focal plane on a substrate surface. A first position sensitive detector receives the laser beam reflected from the substrate surface through the lens to generate a first signal proportional to la ...


8
Kenneth L Staton, Andreas N Dorsel: Scanning system with calibrated detection and method. Agilent Technologies, May 25, 2004: US06740871 (14 worldwide citation)

A self-calibrating scanning system and method are used in the analysis of biomolecules on a microarray. The self-calibrating scanning system comprises an excitation light source, an optical portion, a detection portion and a calibration portion that includes a calibration apparatus and compensation ...


9
John F Corson, Debra A Sillman, Jayati Ghosh, Kenneth L Staton: Signal offset for prevention of data clipping in a molecular array scanner. Agilent Technologies, July 5, 2005: US06914229 (13 worldwide citation)

A method and system for preventing signal clipping in a molecular array scanner by adding an offset signal to the signal generated by the photodetectors and initial stages of signal processing within a molecular array scanner in order to promote the signal above the level where signal information is ...


10
Andreas N Dorsel, Glenda C Delenstarr, Kenneth L Staton, George P Tsai: Reading multi-featured arrays. Agilent Technologies, April 17, 2007: US07205553 (10 worldwide citation)

A method, apparatus, and computer program product for reading fluorescence signals from an array of chemical moieties (such as different sequence peptides or polynucleotides, for example different DNA sequences). In the method the spatial sequence of scanned locations need not be the same as the tem ...