1
Mora Carolynne Melican, Yufu Li, Kelly R Brown, Iksoo Chun, John McAllen III, Alireza Rezania, Angelo G Scopelianos, Murty N Vyakarnam: Reinforced tissue implants and methods of manufacture and use. Ethicon, Nutter McClennen & Fish, July 29, 2003: US06599323 (286 worldwide citation)

A biocompatible tissue implant, as well as methods for making and using such an implant, is provided. Preferably, the tissue implant is bioabsorbable. The tissue implant comprises one or more layers of a bioabsorbable polymeric foam having pores with an open cell structure. The tissue implant also i ...


2
Kelly R Brown, Mark C Zimmerman, Yufu Li: Composite scaffold with post anchor for the repair and regeneration of tissue. Ethicon, September 30, 2003: US06626950 (231 worldwide citation)

A prosthetic implant having a tissue scaffold and a fixation device with a scaffold support and an anchoring post. The anchoring post extends from a surface of the scaffold support at a selected angle with the scaffold support embedded within the scaffold. The scaffold has a porous ceramic phase and ...


3
Dennis D Jamiolkowski, Kelly R Brown, Iksoo Chun, Mora Carolynne Melican: Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof. DePuy Mitek, June 12, 2012: US08197837 (59 worldwide citation)

A biocompatible tissue implant. The tissue implant may be bioabsorbable, consists of a biocompatible polymeric foam. The tissue implant also includes a biocompatible reinforcement member. The polymeric foam and the reinforcement member are soluble in a lyophilizing solvent. The reinforcement may be ...


4
Iksoo Chun, Dennis D Jamiolkowski, Kelly R Brown, Julia Hwang, Francois Binette, Mora Carolynne Melican: Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof. DePuy Mitek, Nutter McClennen & Fish, May 6, 2008: US07368124 (57 worldwide citation)

A biocompatible tissue implant is disclosed. The tissue implant may be bioabsorbable, and is made from a biocompatible polymeric foam. The tissue implant also includes a biocompatible reinforcement member. The polymeric foam and the reinforcement member are soluble in a common solvent.


5
Kelly R Brown, Iksoo Chun, Joseph J Hammer, Victor F Janas, Jennifer Mandanas, Mora C Melican, Alireza Rezania, Mark C Zimmerman: Implantable biodegradable devices for musculoskeletal repair or regeneration. Ethicon, March 20, 2007: US07192604 (49 worldwide citation)

An implantable biodegradable device is disclosed containing a fibrous matrix, the fibrous matrix being constructed from fibers A and fibers B, wherein fibers A biodegrade faster than fibers B, fibers A and fibers B are present in relative amounts and are organized such that the fibrous matrix is pro ...


6
Aruna Nathan, Mora C Melican, Kelly R Brown, Mark C Zimmerman: Bone replacement materials utilizing bioabsorbable liquid polymers. Ethicon, February 28, 2006: US07005136 (12 worldwide citation)

The present invention is directed to bone replacement devices and compositions containing a synthetic, bioabsorbable, biocompatible liquid polymer that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the liquid polymer having a melting point less than ab ...


7
Joseph J Hammer, Joseph H Contiliano, Murty N Vyakarnam, Kelly R Brown: Attachment of absorbable tissue scaffolds to fixation devices. Advanced Technologies and Regenerative Medicine, Roberts Mlotkowski Safran & Cole P C, May 29, 2012: US08187326 (5 worldwide citation)

The present invention relates to tissue scaffold implant devices useful in the repair and/or regeneration of diseased and/or damaged musculoskeletal tissue and that include a tissue scaffold component fixedly attached to a scaffold fixation component via a polymeric adhesive layer, and to methods of ...


8
Aruna Nathan, Mora C Melican, Kelly R Brown, Mark C Zimmerman: Bone replacement materials utilizing bioabsorbable liquid polymers. Audley A Ciamporcero Jr, Johnson & Johnson, October 2, 2003: US20030185871-A1 (1 worldwide citation)

The present invention is directed to bone replacement devices and compositions containing a synthetic, bioabsorbable, biocompatible liquid polymer that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the liquid polymer having a melting point less than ab ...


9
Dennis D Jamiolkowski, Kelly R Brown, Iksoo Chun, Mora Carolynne Melican: Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof. DePuy Mitek, November 25, 2014: US08895045

A biocompatible tissue implant. The tissue implant may be bioabsorbable, consists of a biocompatible polymeric foam. The tissue implant also includes a biocompatible reinforcement member. The polymeric foam and the reinforcement member are soluble in a lyophilizing solvent. The reinforcement may be ...


10
Kelly R Brown, Mora C Melican, Iksoo Chun: Channeled biomedical foams an method for producing same. Ethicon, Emil Richard Skula, March 9, 2010: US07674408

The present invention provides a biomedical, biocompatible, polymeric foam scaffold suitable for use in the repair and regeneration of tissue and which contains located therein a network of, branched channels that are effective to encourage and facilitate vascularization and tissue growth within the ...