1
James E Shapland, Mark B Knudson, Jin Shimada, Keith R Hildebrand: Drug delivery apparatus and method. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, February 1, 1994: US05282785 (294 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall ...


2
Joel R Racchini, James E Shapland, Mark B Knudson, Jin Shimada, Keith R Hildebrand: Porous balloon for selective dilatation and drug delivery. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, October 17, 1995: US05458568 (288 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively wetting a membrane within the device, making the membrane permeable and allowing t ...


3
James E Shapland, Keith R Hildebrand: Simultaneous cardiac pacing and local drug delivery method. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt PA, June 3, 1997: US05634899 (288 worldwide citation)

An apparatus and method for delivering a drug selectively and locally to internal body tissue with a catheter using electric current/voltage controlled in conjunction with active pacing of cardiac activity.


4
James E Shapland, Keith R Hildebrand: Simultaneous cardiac pacing and local drug delivery. Cortrak Medical, Merchant Gould Smith Edell Welter & Schmidt P A, February 2, 1999: US05865787 (228 worldwide citation)

An apparatus and method for delivering a drug selectively and locally to internal body tissue with a catheter using electric current/voltage controlled in conjunction with active pacing of cardiac activity.


5
Keith R Hildebrand: Prostatic drug-delivery catheter. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, May 30, 1995: US05419763 (88 worldwide citation)

A method and apparatus for the treatment of a prostate gland which isolates the prostatic urethra from the membranous urethra and the bladder so that fluid may be transported into the prostatic ducts without compromising the openings to the prostatic ducts. One preferred embodiment incorporates ball ...


6
Keith R Hildebrand, Michael R Ujhelyi, Xiaohong Zhou, Daniel C Sigg, Linda M Page: Delivery of a sympatholytic cardiovascular agent to the central nervous system. Medtronic, Paul H McDowell, Steve Bauer, June 24, 2008: US07390311 (56 worldwide citation)

A sympatholytic cardiovascular agent delivered by a drug delivery pump to a central nervous system site to alleviate symptoms of acute or chronic cardiac insult or impaired cardiac performance. The drug delivery pump can be external or implantable infusion pump (IIP) coupled with a drug infusion cat ...


7
Keith R Hildebrand, Michael R Ujhelyi, Xiaohong Zhou, Daniel C Sigg, Linda M Page: Delivery of a sympatholytic cardiovascular agent to the central nervous system to counter heart failure and pathologies associated with heart failure. Medtronic, Paul H McDowall, Girma Wolde Michael, June 19, 2007: US07232435 (44 worldwide citation)

A sympatholytic cardiovascular agent delivered by a drug delivery pump to a central nervous system site to alleviate symptoms and otherwise treat heart failure (HF) and pathologies associated with HF. The drug delivery pump can be external or implantable infusion pump (IIP) coupled with a drug infus ...


8
Keith R Hildebrand, J Edward Shapland: Delivering an agent to an organ. Iotek, Merchant Gould Smith Edell Welter & Schmidt P A, May 12, 1998: US05749845 (43 worldwide citation)

A method of delivering an agent to an organ from the group consisting of a bladder or a uterus. The method utilizes a catheter having an inflatable portion. The inflatable portion of the catheter is inserted into the organ and is inflated so that it expands the organ. The agent is then delivered fro ...


9
Keith R Hildebrand, Jan Ellen O Fowler, Dezso K Levius: Iotek, Merchant Gould Smith Edell Welter & Schmidt P A, January 19, 1999: US05861431 (24 worldwide citation)

The present invention provides a method of treating incontinence in a patient that has a bladder and a urethra. The urethra forms a lumen for draining the bladder. The method comprises the steps of delivering an agent into the lumen and passing the agent from the lumen to internal body tissue. The a ...


10
William C Houghton, Keith R Hildebrand, Martin B Finkelstein, Frederick J Foley: Iontophoretic agent delivery to the female reproductive tract. Iotek, Merchant & Gould P C, October 31, 2000: US06139538 (15 worldwide citation)

An apparatus for iontophoretically delivering an agent to a patient having a uterus and a cervix. The apparatus comprises a probe sized to fit within the cervical canal. A cervical cap has an inner surface. The probe projects from the inner surface. A first electrode has a first portion operably con ...