1
Yasuharu Noishiki, Kazuhiko Kodaira, Masayasu Furuse, Teruo Miyata: Method of preparing antithrombogenic medical materials. Koken, Armstrong Nikaido Marmelstein & Kubovcik, February 21, 1989: US04806595 (97 worldwide citation)

In a method of preparing an antithrombogenic medical material having a heparinized collagen as an antithrombogenic component, there is provided a method comprising the steps of fixing a protamine to a collagen through a polyepoxy compound, and heparinizing the collagen by fixing heparin to the prota ...


2
Teruo Miyata, Kazuhiko Kodaira, Masayasu Furuse, Yasuharu Noishiki: Hemostatic agent composed of collagen/gelatin and protamine. Koken, Sherman and Shalloway, June 7, 1988: US04749689 (74 worldwide citation)

This invention relates to a hemostatic agent used in surgical operations, which can be produced in two ways: one blending collagen/gelatin with protamine, the other blending collagen/gelatin with protamine and a bi-functional cross-linking agent so as to make said collagen/gelatin have a covalent bo ...


3
Teruo Miyata, Kazuhiko Kodaira, Hitoshi Higashijima, Takashi Kimura, Yasuharu Noishiki: Biomaterial comprising a composite material of a chitosan derivative and collagen derivative. Katakura Chikkarin, Koken, Wenderoth Lind & Ponack, May 26, 1992: US05116824 (57 worldwide citation)

A biomaterial excellent in biocompatibility comprising a composite material of an N-acylchitosan and collagen is described. This biomaterial is suitable for used as a wound dressing material, vascular prosthesis, artificial skin or hemostatic agent.


4
Yasuharu Noishiki, Kazuhiko Kodaira, Masayasu Furuse, Teruo Miyata, Takeaki Miyamoto, Hiraku Ito: Production process of an antithrombogenic and antiadhesive material for medical use. Koken Company, Sherman and Shalloway, September 1, 1987: US04690973 (10 worldwide citation)

This invention concerns a production process of an antithrombogenic and antiadhesive material which can favorably be used as artificial blood vessels, artificial valves, grafting patches for cardiovascular organs, artificial heart catheters and so on. The gist of this invention is constructed substa ...